Details for gene set REACTOME_PROTEIN_LOCALIZATION[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	WT
GeneSet	REACTOME_PROTEIN_LOCALIZATION
Enrichment Score (ES)	-0.40190616
Normalized Enrichment Score (NES)	-1.6165136
Nominal p-value	0.07905138
FDR q-value	0.6745272
FWER p-Value	0.942

Fig 1: Enrichment plot: REACTOME_PROTEIN_LOCALIZATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Gdap1	Gdap1	1045	0.854	-0.0115	No
2	Cyb5a	Cyb5a	2851	0.534	-0.0646	No
3	Decr2	Decr2	3155	0.503	-0.0589	No
4	Prnp	Prnp	3495	0.472	-0.0557	No
5	Usp9x	Usp9x	3973	0.432	-0.0594	No
6	Acot4	Acot4	4236	0.410	-0.0553	No
7	Crot	Crot	4664	0.379	-0.0589	No
8	Acox2	Acox2	5467	0.329	-0.0793	No
9	Paox	Paox	5966	0.300	-0.0886	No
10	Hacl1	Hacl1	5996	0.299	-0.0791	No
11	Hmgcl	Hmgcl	6724	0.258	-0.0990	No
12	Acot8	Acot8	6835	0.253	-0.0945	No
13	Aldh3a2	Aldh3a2	7129	0.238	-0.0977	No
14	Rps27a	Rps27a	7958	0.201	-0.1237	No
15	Stx1a	Stx1a	8332	0.185	-0.1320	No
16	Hscb	Hscb	8972	0.160	-0.1519	No
17	Serp1	Serp1	9412	0.142	-0.1644	No
18	Ldhd	Ldhd	9844	0.125	-0.1772	No
19	Sgta	Sgta	9857	0.124	-0.1733	No
20	Nudt19	Nudt19	10089	0.115	-0.1785	No
21	Ubb	Ubb	10421	0.102	-0.1881	No
22	Acot3	Acot3	10485	0.099	-0.1871	No
23	Acox3	Acox3	10909	0.083	-0.2011	No
24	Lonp2	Lonp2	11977	0.045	-0.2421	No
25	Acaa1b	Acaa1b	12362	0.031	-0.2564	No
26	Pex16	Pex16	12465	0.028	-0.2595	No
27	Sec61b	Sec61b	12499	0.027	-0.2599	No
28	Acbd5	Acbd5	12730	0.019	-0.2684	No
29	Stx5a	Stx5a	13025	0.008	-0.2799	No
30	Ube2d3	Ube2d3	13583	-0.012	-0.3017	No
31	Fis1	Fis1	13685	-0.016	-0.3052	No
32	Pex5	Pex5	13931	-0.024	-0.3141	No
33	Uba52rt	Uba52rt	14172	-0.033	-0.3225	No
34	Pex10	Pex10	14352	-0.039	-0.3283	No
35	Ide	Ide	14583	-0.048	-0.3358	No
36	Ube2d2a	Ube2d2a	15018	-0.063	-0.3509	No
37	Ehhadh	Ehhadh	15210	-0.071	-0.3560	No
38	Uba52	Uba52	15308	-0.074	-0.3573	No
39	Pecr	Pecr	15558	-0.083	-0.3643	No
40	Pex14	Pex14	15723	-0.089	-0.3677	No
41	Nos2	Nos2	15732	-0.089	-0.3648	No
42	App	App	15780	-0.090	-0.3635	No
43	Tysnd1	Tysnd1	15808	-0.092	-0.3613	No
44	Pex1	Pex1	16606	-0.121	-0.3889	No
45	Slc25a17	Slc25a17	16643	-0.123	-0.3860	No
46	Pex3	Pex3	16687	-0.124	-0.3833	No
47	Ephx2	Ephx2	16691	-0.124	-0.3790	No
48	Ubc	Ubc	16741	-0.126	-0.3765	No
49	Ndufb8	Ndufb8	16766	-0.127	-0.3729	No
50	Hmox1	Hmox1	17058	-0.139	-0.3796	No
51	Acox1	Acox1	17147	-0.143	-0.3781	No
52	Dhrs4	Dhrs4	17401	-0.153	-0.3828	No
53	Gnpat	Gnpat	17880	-0.173	-0.3958	Yes
54	Pex12	Pex12	18022	-0.179	-0.3951	Yes
55	Vapa	Vapa	18113	-0.183	-0.3922	Yes
56	Pex13	Pex13	18160	-0.185	-0.3874	Yes
57	Zfand6	Zfand6	18349	-0.193	-0.3881	Yes
58	Cat	Cat	18350	-0.193	-0.3812	Yes
59	Fxn	Fxn	18679	-0.207	-0.3870	Yes
60	Sec61g	Sec61g	18907	-0.218	-0.3883	Yes
61	Ube2d1	Ube2d1	19000	-0.221	-0.3841	Yes
62	Idh1	Idh1	19028	-0.222	-0.3773	Yes
63	Pxmp4	Pxmp4	19521	-0.245	-0.3883	Yes
64	Ube2j2	Ube2j2	19618	-0.251	-0.3832	Yes
65	Pex19	Pex19	19697	-0.256	-0.3773	Yes
66	Pex26	Pex26	19775	-0.259	-0.3711	Yes
67	Scp2	Scp2	19998	-0.271	-0.3704	Yes
68	Pex11b	Pex11b	20073	-0.275	-0.3636	Yes
69	Vamp2	Vamp2	20707	-0.310	-0.3779	Yes
70	Hsd17b4	Hsd17b4	20741	-0.312	-0.3681	Yes
71	Atad1	Atad1	21043	-0.330	-0.3685	Yes
72	Phyh	Phyh	21158	-0.336	-0.3611	Yes
73	Ddo	Ddo	21177	-0.338	-0.3498	Yes
74	Coq2	Coq2	21471	-0.358	-0.3488	Yes
75	Pitrm1	Pitrm1	21595	-0.368	-0.3406	Yes
76	Emd	Emd	21664	-0.373	-0.3301	Yes
77	Pex6	Pex6	21900	-0.391	-0.3256	Yes
78	Pex7	Pex7	22016	-0.399	-0.3160	Yes
79	Amacr	Amacr	22163	-0.411	-0.3073	Yes
80	Baat	Baat	22261	-0.420	-0.2963	Yes
81	Mlycd	Mlycd	22448	-0.436	-0.2882	Yes
82	Abcd1	Abcd1	22494	-0.441	-0.2743	Yes
83	Pipox	Pipox	22547	-0.448	-0.2605	Yes
84	Abcd2	Abcd2	22560	-0.450	-0.2450	Yes
85	Eci2	Eci2	22825	-0.478	-0.2386	Yes
86	Pex2	Pex2	23231	-0.526	-0.2361	Yes
87	Atp5f1b	Atp5f1b	23271	-0.531	-0.2188	Yes
88	Acot2	Acot2	23356	-0.542	-0.2029	Yes
89	Atp5mc3	Atp5mc3	23756	-0.610	-0.1972	Yes
90	Hspd1	Hspd1	24017	-0.671	-0.1838	Yes
91	Crat	Crat	24117	-0.702	-0.1628	Yes
92	Mpv17	Mpv17	24154	-0.712	-0.1390	Yes
93	Gstk1	Gstk1	24487	-0.827	-0.1229	Yes
94	Abcd3	Abcd3	24595	-0.885	-0.0957	Yes
95	Nudt7	Nudt7	24648	-0.916	-0.0652	Yes
96	Acot1	Acot1	24805	-1.091	-0.0327	Yes
97	Ech1	Ech1	24903	-1.260	0.0082	Yes

Fig 2: REACTOME_PROTEIN_LOCALIZATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_PROTEIN_LOCALIZATION: Random ES distribution   
Gene set null distribution of ES for REACTOME_PROTEIN_LOCALIZATION