Details for gene set WP_ERBB_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	WP_ERBB_SIGNALING_PATHWAY
Enrichment Score (ES)	0.40649128
Normalized Enrichment Score (NES)	1.5673977
Nominal p-value	0.034979425
FDR q-value	1.0
FWER p-Value	0.635

Fig 1: Enrichment plot: WP_ERBB_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Nrg1	Nrg1	27	2.177	0.1147	Yes
2	Myc	Myc	211	1.433	0.1836	Yes
3	Tgfa	Tgfa	541	1.087	0.2283	Yes
4	Ereg	Ereg	687	0.999	0.2756	Yes
5	Nrg4	Nrg4	693	0.995	0.3283	Yes
6	Src	Src	954	0.889	0.3652	Yes
7	Btc	Btc	2467	0.581	0.3358	Yes
8	Jun	Jun	2818	0.539	0.3505	Yes
9	Cdkn1a	Cdkn1a	2946	0.523	0.3732	Yes
10	Eif4ebp1	Eif4ebp1	3062	0.512	0.3958	Yes
11	Areg	Areg	3433	0.478	0.4065	Yes
12	Hbegf	Hbegf	5341	0.337	0.3483	No
13	Erbb2	Erbb2	6031	0.296	0.3366	No
14	Egfr	Egfr	8592	0.174	0.2437	No
15	Shc2	Shc2	9136	0.153	0.2302	No
16	Sos1	Sos1	9483	0.139	0.2238	No
17	Pak4	Pak4	9596	0.134	0.2264	No
18	Erbb3	Erbb3	9712	0.129	0.2287	No
19	Pik3r5	Pik3r5	9785	0.127	0.2326	No
20	Bad	Bad	11045	0.078	0.1865	No
21	Crk	Crk	11842	0.049	0.1573	No
22	Elk1	Elk1	14138	-0.032	0.0675	No
23	Map2k1	Map2k1	14564	-0.047	0.0530	No
24	Hras	Hras	15263	-0.073	0.0290	No
25	Gsk3b	Gsk3b	15642	-0.086	0.0185	No
26	Akt3	Akt3	15857	-0.093	0.0149	No
27	Cblc	Cblc	16090	-0.103	0.0111	No
28	Ptk2	Ptk2	16385	-0.113	0.0054	No
29	Grb2	Grb2	17172	-0.143	-0.0183	No
30	Plcg1	Plcg1	18355	-0.193	-0.0552	No
31	Mapk1	Mapk1	18437	-0.197	-0.0480	No
32	Mtor	Mtor	18894	-0.217	-0.0546	No
33	Mapk8	Mapk8	19234	-0.232	-0.0558	No
34	Nck1	Nck1	19345	-0.236	-0.0477	No
35	Prkca	Prkca	19435	-0.241	-0.0384	No
36	Araf	Araf	19699	-0.256	-0.0353	No
37	Camk2a	Camk2a	20094	-0.276	-0.0364	No
38	Cdkn1b	Cdkn1b	20233	-0.283	-0.0268	No
39	Map2k7	Map2k7	20790	-0.314	-0.0323	No
40	Stat5a	Stat5a	20939	-0.322	-0.0211	No
41	Abl1	Abl1	21574	-0.366	-0.0269	No
42	Gab1	Gab1	21767	-0.380	-0.0144	No
43	Nrg2	Nrg2	24411	-0.794	-0.0776	No
44	Erbb4	Erbb4	24541	-0.851	-0.0376	No
45	Egf	Egf	24838	-1.130	0.0107	No

Fig 2: WP_ERBB_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_ERBB_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for WP_ERBB_SIGNALING_PATHWAY