Details for gene set WP_MAPK_CASCADE[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	WT
GeneSet	WP_MAPK_CASCADE
Enrichment Score (ES)	-0.28022885
Normalized Enrichment Score (NES)	-1.0879649
Nominal p-value	0.35437882
FDR q-value	0.8755985
FWER p-Value	0.994

Fig 1: Enrichment plot: WP_MAPK_CASCADE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Jun	Jun	2818	0.539	-0.0364	No
2	Mapk12	Mapk12	2982	0.520	0.0304	No
3	Rasa3	Rasa3	3882	0.438	0.0563	No
4	Rras	Rras	4085	0.422	0.1078	No
5	Map3k12	Map3k12	5084	0.351	0.1175	No
6	Nras	Nras	8316	0.186	0.0149	No
7	Mbp	Mbp	11603	0.058	-0.1080	No
8	Braf	Braf	12163	0.038	-0.1248	No
9	Map3k2	Map3k2	13446	-0.007	-0.1750	No
10	Elk1	Elk1	14138	-0.032	-0.1980	No
11	Map2k1	Map2k1	14564	-0.047	-0.2083	No
12	Hras	Hras	15263	-0.073	-0.2259	No
13	Kras	Kras	16073	-0.102	-0.2438	No
14	Map3k1	Map3k1	16987	-0.136	-0.2610	Yes
15	Map2k6	Map2k6	17471	-0.155	-0.2583	Yes
16	Sipa1	Sipa1	17518	-0.157	-0.2380	Yes
17	Plcb3	Plcb3	18137	-0.184	-0.2367	Yes
18	Mapk1	Mapk1	18437	-0.197	-0.2208	Yes
19	Map2	Map2	18656	-0.207	-0.2004	Yes
20	Mapk3	Mapk3	19068	-0.224	-0.1851	Yes
21	Map3k3	Map3k3	19665	-0.254	-0.1731	Yes
22	Araf	Araf	19699	-0.256	-0.1384	Yes
23	Map2k2	Map2k2	19750	-0.258	-0.1040	Yes
24	Map2k4	Map2k4	21120	-0.334	-0.1114	Yes
25	Map2k3	Map2k3	21250	-0.343	-0.0683	Yes
26	Mapk10	Mapk10	21723	-0.377	-0.0340	Yes
27	Raf1	Raf1	22482	-0.440	-0.0022	Yes
28	Mapk14	Mapk14	24295	-0.757	0.0324	Yes

Fig 2: WP_MAPK_CASCADE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_MAPK_CASCADE: Random ES distribution   
Gene set null distribution of ES for WP_MAPK_CASCADE