Details for gene set WP_ONECARBON_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	WP_ONECARBON_METABOLISM
Enrichment Score (ES)	0.37909883
Normalized Enrichment Score (NES)	1.3618128
Nominal p-value	0.12601626
FDR q-value	1.0
FWER p-Value	0.926

Fig 1: Enrichment plot: WP_ONECARBON_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Shmt1	Shmt1	19	2.339	0.1986	Yes
2	Mthfd2	Mthfd2	631	1.027	0.2617	Yes
3	Folh1	Folh1	694	0.995	0.3440	Yes
4	Atic	Atic	2343	0.597	0.3292	Yes
5	Mthfs	Mthfs	2361	0.594	0.3791	Yes
6	Tyms	Tyms	4881	0.365	0.3097	No
7	Ehmt2	Ehmt2	6000	0.298	0.2906	No
8	Ahcy	Ahcy	7390	0.227	0.2545	No
9	Ahcyl2	Ahcyl2	7455	0.224	0.2710	No
10	Dnmt3b	Dnmt3b	9595	0.134	0.1972	No
11	Mthfd1l	Mthfd1l	11098	0.076	0.1437	No
12	Ftcd	Ftcd	12443	0.028	0.0926	No
13	Dhfr	Dhfr	13860	-0.021	0.0379	No
14	Mthfr	Mthfr	13916	-0.023	0.0377	No
15	Mtfmt	Mtfmt	14176	-0.034	0.0303	No
16	Tcn2	Tcn2	14376	-0.040	0.0258	No
17	Mtrr	Mtrr	15232	-0.072	-0.0022	No
18	Gart	Gart	15937	-0.097	-0.0220	No
19	Mthfd1	Mthfd1	17208	-0.145	-0.0603	No
20	Dnmt1	Dnmt1	18131	-0.184	-0.0814	No
21	Shmt2	Shmt2	18278	-0.190	-0.0711	No
22	Aldh1l1	Aldh1l1	18941	-0.219	-0.0788	No
23	Mat2b	Mat2b	19319	-0.235	-0.0738	No
24	Ehmt1	Ehmt1	19422	-0.240	-0.0574	No
25	Amt	Amt	19429	-0.240	-0.0372	No
26	Dnmt3a	Dnmt3a	21622	-0.370	-0.0931	No
27	Mtr	Mtr	25099	-2.722	0.0003	No

Fig 2: WP_ONECARBON_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_ONECARBON_METABOLISM: Random ES distribution   
Gene set null distribution of ES for WP_ONECARBON_METABOLISM