Details for gene set WP_P53

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	WP_P53_SIGNALING
Enrichment Score (ES)	0.48132995
Normalized Enrichment Score (NES)	1.5839511
Nominal p-value	0.018404908
FDR q-value	1.0
FWER p-Value	0.603

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Rprm	Rprm	105	1.750	0.0738	Yes
2	Bbc3	Bbc3	249	1.366	0.1290	Yes
3	Ccnd2	Ccnd2	403	1.195	0.1761	Yes
4	Perp	Perp	688	0.997	0.2092	Yes
5	Igf1	Igf1	714	0.982	0.2520	Yes
6	Gtse1	Gtse1	1003	0.874	0.2794	Yes
7	Adgrb1	Adgrb1	1779	0.681	0.2788	Yes
8	Zmat3	Zmat3	2251	0.611	0.2872	Yes
9	Igfbp3	Igfbp3	2388	0.591	0.3081	Yes
10	Atm	Atm	2484	0.579	0.3301	Yes
11	Sesn2	Sesn2	2669	0.557	0.3476	Yes
12	Chek1	Chek1	2902	0.529	0.3619	Yes
13	Cdkn1a	Cdkn1a	2946	0.523	0.3835	Yes
14	Ccnd3	Ccnd3	3540	0.467	0.3806	Yes
15	Cdk6	Cdk6	3884	0.438	0.3864	Yes
16	Pmaip1	Pmaip1	4050	0.425	0.3988	Yes
17	Apaf1	Apaf1	4244	0.410	0.4094	Yes
18	Bid	Bid	4255	0.409	0.4272	Yes
19	Pidd1	Pidd1	4509	0.390	0.4345	Yes
20	Sfn	Sfn	4566	0.387	0.4495	Yes
21	Ccnb1	Ccnb1	5211	0.345	0.4391	Yes
22	Thbs1	Thbs1	5535	0.324	0.4407	Yes
23	Pten	Pten	5905	0.304	0.4395	Yes
24	Cdk1	Cdk1	6047	0.296	0.4470	Yes
25	Mdm4	Mdm4	6280	0.282	0.4503	Yes
26	Mdm2	Mdm2	6351	0.278	0.4599	Yes
27	Ccne1	Ccne1	6414	0.275	0.4697	Yes
28	Atr	Atr	6657	0.262	0.4717	Yes
29	Bax	Bax	6900	0.250	0.4732	Yes
30	Ccng2	Ccng2	6971	0.246	0.4813	Yes
31	Rrm2b	Rrm2b	8149	0.193	0.4429	No
32	Cdkn2a	Cdkn2a	8169	0.192	0.4507	No
33	Serpine1	Serpine1	8273	0.188	0.4550	No
34	Gadd45b	Gadd45b	8481	0.179	0.4547	No
35	Sesn3	Sesn3	9537	0.137	0.4187	No
36	Casp9	Casp9	10396	0.102	0.3890	No
37	Ppm1d	Ppm1d	10691	0.091	0.3813	No
38	Sesn1	Sesn1	11769	0.051	0.3406	No
39	Trp53	Trp53	11872	0.048	0.3387	No
40	Casp8	Casp8	11927	0.046	0.3386	No
41	Gadd45g	Gadd45g	12033	0.043	0.3363	No
42	Rchy1	Rchy1	12551	0.025	0.3168	No
43	Shisa5	Shisa5	13239	0.000	0.2894	No
44	Ccng1	Ccng1	13971	-0.026	0.2613	No
45	Ccnb2	Ccnb2	14381	-0.040	0.2468	No
46	Ei24	Ei24	14857	-0.058	0.2304	No
47	Ddb2	Ddb2	15151	-0.068	0.2218	No
48	Tsc2	Tsc2	15183	-0.070	0.2237	No
49	Ccnd1	Ccnd1	15281	-0.073	0.2231	No
50	Rrm2	Rrm2	15737	-0.089	0.2089	No
51	Fas	Fas	15847	-0.093	0.2086	No
52	Siah1a	Siah1a	15922	-0.096	0.2100	No
53	Gadd45a	Gadd45a	16008	-0.099	0.2110	No
54	Cop1	Cop1	16649	-0.123	0.1909	No
55	Casp3	Casp3	17391	-0.152	0.1681	No
56	Cyct	Cyct	18739	-0.210	0.1237	No
57	Siah1b	Siah1b	19313	-0.235	0.1113	No
58	Cd82	Cd82	20541	-0.300	0.0757	No
59	Cycs	Cycs	21589	-0.368	0.0503	No
60	Ccne2	Ccne2	22352	-0.428	0.0389	No
61	Steap3	Steap3	23039	-0.501	0.0338	No
62	Cdk2	Cdk2	23131	-0.512	0.0530	No
63	Chek2	Chek2	23598	-0.580	0.0603	No