Details for gene set WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY
Enrichment Score (ES)	0.3701712
Normalized Enrichment Score (NES)	1.2323159
Nominal p-value	0.2041237
FDR q-value	1.0
FWER p-Value	0.978

Fig 1: Enrichment plot: WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Degs2	Degs2	443	1.160	0.1619	Yes
2	Cers6	Cers6	967	0.886	0.2781	Yes
3	Ugcg	Ugcg	1505	0.733	0.3702	Yes
4	Sphk1	Sphk1	3516	0.470	0.3627	No
5	Cers3	Cers3	6708	0.259	0.2756	No
6	Cers2	Cers2	6818	0.253	0.3105	No
7	Kdsr	Kdsr	7041	0.242	0.3391	No
8	Sgpl1	Sgpl1	7525	0.220	0.3539	No
9	Sptlc2	Sptlc2	7989	0.199	0.3663	No
10	Sptlc1	Sptlc1	10295	0.107	0.2910	No
11	Cers1	Cers1	10559	0.097	0.2954	No
12	Asah1	Asah1	10845	0.085	0.2973	No
13	Sgpp2	Sgpp2	11404	0.065	0.2851	No
14	Sgms2	Sgms2	11761	0.052	0.2789	No
15	Sgms1	Sgms1	12690	0.020	0.2450	No
16	Degs1	Degs1	14058	-0.029	0.1950	No
17	Cers4	Cers4	14698	-0.053	0.1777	No
18	Plpp1	Plpp1	16129	-0.104	0.1368	No
19	Sgpp1	Sgpp1	16239	-0.108	0.1491	No
20	Cers5	Cers5	16351	-0.112	0.1620	No
21	Sphk2	Sphk2	16830	-0.130	0.1630	No
22	Cerk	Cerk	17451	-0.154	0.1622	No
23	Plpp3	Plpp3	21082	-0.332	0.0689	No
24	Smpd1	Smpd1	23666	-0.591	0.0574	No

Fig 2: WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY: Random ES distribution   
Gene set null distribution of ES for WP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY