Details for gene set WP_SPHINGOLIPID_METABOLISM_OVERVIEW[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WT.KO_vs_WT.cls#KO_versus_WT.KO_vs_WT.cls#KO_versus_WT_repos
Phenotype	KO_vs_WT.cls#KO_versus_WT_repos
Upregulated in class	KO
GeneSet	WP_SPHINGOLIPID_METABOLISM_OVERVIEW
Enrichment Score (ES)	0.378361
Normalized Enrichment Score (NES)	1.237565
Nominal p-value	0.19135803
FDR q-value	1.0
FWER p-Value	0.978

Fig 1: Enrichment plot: WP_SPHINGOLIPID_METABOLISM_OVERVIEW   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Degs2	Degs2	443	1.160	0.1650	Yes
2	Cers6	Cers6	967	0.886	0.2837	Yes
3	Ugcg	Ugcg	1505	0.733	0.3777	Yes
4	Sphk1	Sphk1	3516	0.470	0.3716	Yes
5	Cers3	Cers3	6708	0.259	0.2852	Yes
6	Cers2	Cers2	6818	0.253	0.3208	Yes
7	Kdsr	Kdsr	7041	0.242	0.3500	Yes
8	Sgpl1	Sgpl1	7525	0.220	0.3654	Yes
9	Sptlc2	Sptlc2	7989	0.199	0.3784	Yes
10	Sptlc1	Sptlc1	10295	0.107	0.3033	No
11	Cers1	Cers1	10559	0.097	0.3081	No
12	Asah1	Asah1	10845	0.085	0.3102	No
13	Sgpp2	Sgpp2	11404	0.065	0.2981	No
14	Sgms2	Sgms2	11761	0.052	0.2921	No
15	Sgms1	Sgms1	12690	0.020	0.2582	No
16	Degs1	Degs1	14058	-0.029	0.2083	No
17	Cers4	Cers4	14698	-0.053	0.1912	No
18	Plpp1	Plpp1	16129	-0.104	0.1505	No
19	Sgpp1	Sgpp1	16239	-0.108	0.1631	No
20	Sphk2	Sphk2	16830	-0.130	0.1601	No
21	Cerk	Cerk	17451	-0.154	0.1597	No
22	Plpp3	Plpp3	21082	-0.332	0.0673	No
23	Smpd1	Smpd1	23666	-0.591	0.0574	No

Fig 2: WP_SPHINGOLIPID_METABOLISM_OVERVIEW   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_SPHINGOLIPID_METABOLISM_OVERVIEW: Random ES distribution   
Gene set null distribution of ES for WP_SPHINGOLIPID_METABOLISM_OVERVIEW