Details for gene set BIOCARTA_ATRBRCA_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	BIOCARTA_ATRBRCA_PATHWAY
Enrichment Score (ES)	-0.5793984
Normalized Enrichment Score (NES)	-1.5254315
Nominal p-value	0.05357143
FDR q-value	0.2999088
FWER p-Value	0.648

Fig 1: Enrichment plot: BIOCARTA_ATRBRCA_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Fancc	Fancc	5484	0.249	-0.1822	No
2	Hus1	Hus1	9963	0.051	-0.3616	No
3	Rad50	Rad50	11119	0.010	-0.4086	No
4	Rad1	Rad1	11737	-0.011	-0.4324	No
5	Nbn	Nbn	11849	-0.016	-0.4340	No
6	Chek2	Chek2	12207	-0.028	-0.4435	No
7	Brca2	Brca2	13090	-0.060	-0.4689	No
8	Rad9a	Rad9a	14430	-0.112	-0.5032	No
9	Atr	Atr	15767	-0.165	-0.5268	No
10	Trex1	Trex1	17012	-0.222	-0.5350	Yes
11	Mre11a	Mre11a	17135	-0.228	-0.4947	Yes
12	Trp53	Trp53	18947	-0.319	-0.5077	Yes
13	Fancg	Fancg	19028	-0.323	-0.4465	Yes
14	Rad17	Rad17	19197	-0.334	-0.3869	Yes
15	Fancd2	Fancd2	19381	-0.347	-0.3255	Yes
16	Fanca	Fanca	19685	-0.368	-0.2648	Yes
17	Brca1	Brca1	20642	-0.453	-0.2147	Yes
18	Chek1	Chek1	22334	-0.739	-0.1387	Yes
19	Rad51	Rad51	22908	-0.973	0.0314	Yes

Fig 2: BIOCARTA_ATRBRCA_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_ATRBRCA_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_ATRBRCA_PATHWAY