Details for gene set BIOCARTA_ERK_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	BIOCARTA_ERK_PATHWAY
Enrichment Score (ES)	-0.43318468
Normalized Enrichment Score (NES)	-1.6404537
Nominal p-value	0.011857707
FDR q-value	0.22460523
FWER p-Value	0.432

Fig 1: Enrichment plot: BIOCARTA_ERK_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Rps6ka5	Rps6ka5	985	0.932	0.0731	No
2	Ngf	Ngf	4081	0.351	-0.0146	No
3	Mknk2	Mknk2	4503	0.319	0.0069	No
4	Raf1	Raf1	5546	0.246	-0.0069	No
5	Mapk3	Mapk3	5607	0.243	0.0204	No
6	Sos1	Sos1	6026	0.221	0.0299	No
7	Stat3	Stat3	6366	0.204	0.0407	No
8	Map2k1	Map2k1	7527	0.150	0.0101	No
9	Mknk1	Mknk1	7745	0.139	0.0180	No
10	Ptprr	Ptprr	8492	0.108	-0.0003	No
11	Mapk1	Mapk1	8711	0.099	0.0027	No
12	Elk1	Elk1	9008	0.088	0.0010	No
13	Hras	Hras	10115	0.045	-0.0402	No
14	Pdgfra	Pdgfra	10278	0.039	-0.0422	No
15	Shc1	Shc1	10536	0.030	-0.0495	No
16	Grb2	Grb2	11511	-0.004	-0.0902	No
17	Map2k2	Map2k2	12014	-0.021	-0.1088	No
18	Ppp2ca	Ppp2ca	13141	-0.061	-0.1489	No
19	Gnas	Gnas	14312	-0.107	-0.1853	No
20	Egfr	Egfr	14996	-0.135	-0.1975	No
21	Rps6ka1	Rps6ka1	20391	-0.427	-0.3732	Yes
22	Igf1r	Igf1r	21810	-0.615	-0.3575	Yes
23	Myc	Myc	22951	-0.997	-0.2829	Yes
24	Itgb1	Itgb1	23103	-1.116	-0.1518	Yes
25	Ngfr	Ngfr	23363	-1.419	0.0121	Yes

Fig 2: BIOCARTA_ERK_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_ERK_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_ERK_PATHWAY