Details for gene set BIOCARTA_GH_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	BIOCARTA_GH_PATHWAY
Enrichment Score (ES)	0.40416452
Normalized Enrichment Score (NES)	1.3885865
Nominal p-value	0.09514563
FDR q-value	0.43362555
FWER p-Value	0.855

Fig 1: Enrichment plot: BIOCARTA_GH_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Irs1	Irs1	1207	0.829	0.0666	Yes
2	Ptpn6	Ptpn6	1228	0.818	0.1819	Yes
3	Pik3r1	Pik3r1	1878	0.634	0.2446	Yes
4	Stat5b	Stat5b	3140	0.436	0.2532	Yes
5	Insr	Insr	3900	0.367	0.2731	Yes
6	Ghr	Ghr	4898	0.289	0.2719	Yes
7	Pik3ca	Pik3ca	5000	0.282	0.3077	Yes
8	Plcg1	Plcg1	5128	0.274	0.3413	Yes
9	Raf1	Raf1	5546	0.246	0.3586	Yes
10	Mapk3	Mapk3	5607	0.243	0.3905	Yes
11	Sos1	Sos1	6026	0.221	0.4042	Yes
12	Slc2a4	Slc2a4	7463	0.152	0.3650	No
13	Map2k1	Map2k1	7527	0.150	0.3837	No
14	Mapk1	Mapk1	8711	0.099	0.3477	No
15	Prkcb	Prkcb	8829	0.094	0.3561	No
16	Hras	Hras	10115	0.045	0.3081	No
17	Shc1	Shc1	10536	0.030	0.2945	No
18	Socs1	Socs1	11022	0.013	0.2759	No
19	Grb2	Grb2	11511	-0.004	0.2558	No
20	Srf	Srf	13411	-0.071	0.1855	No
21	Pik3cg	Pik3cg	14778	-0.126	0.1456	No
22	Jak2	Jak2	15840	-0.168	0.1246	No
23	Prkca	Prkca	16483	-0.197	0.1254	No
24	Hnf1a	Hnf1a	18286	-0.284	0.0895	No
25	Rps6ka1	Rps6ka1	20391	-0.427	0.0612	No
26	Stat5a	Stat5a	21349	-0.540	0.0974	No

Fig 2: BIOCARTA_GH_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_GH_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_GH_PATHWAY