Details for gene set BIOCARTA_HER2_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	BIOCARTA_HER2_PATHWAY
Enrichment Score (ES)	0.45187533
Normalized Enrichment Score (NES)	1.4640527
Nominal p-value	0.09448819
FDR q-value	0.5609567
FWER p-Value	0.737

Fig 1: Enrichment plot: BIOCARTA_HER2_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Erbb4	Erbb4	676	1.149	0.1760	Yes
2	Pik3r1	Pik3r1	1878	0.634	0.2381	Yes
3	Grip1	Grip1	2468	0.527	0.3070	Yes
4	Il6ra	Il6ra	4655	0.306	0.2690	Yes
5	Pik3ca	Pik3ca	5000	0.282	0.3046	Yes
6	Raf1	Raf1	5546	0.246	0.3254	Yes
7	Mapk3	Mapk3	5607	0.243	0.3660	Yes
8	Il6st	Il6st	5711	0.237	0.4039	Yes
9	Sos1	Sos1	6026	0.221	0.4299	Yes
10	Stat3	Stat3	6366	0.204	0.4519	Yes
11	Map2k1	Map2k1	7527	0.150	0.4295	No
12	Esr1	Esr1	8328	0.114	0.4158	No
13	Il6	Il6	8669	0.101	0.4194	No
14	Mapk1	Mapk1	8711	0.099	0.4353	No
15	Hras	Hras	10115	0.045	0.3839	No
16	Shc1	Shc1	10536	0.030	0.3714	No
17	Grb2	Grb2	11511	-0.004	0.3309	No
18	Ep300	Ep300	12226	-0.029	0.3058	No
19	Erbb2	Erbb2	12556	-0.040	0.2990	No
20	Pik3cg	Pik3cg	14778	-0.126	0.2274	No
21	Egfr	Egfr	14996	-0.135	0.2423	No
22	Carm1	Carm1	16886	-0.216	0.2007	No
23	Erbb3	Erbb3	20878	-0.480	0.1173	No

Fig 2: BIOCARTA_HER2_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_HER2_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_HER2_PATHWAY