Details for gene set BIOCARTA_HIVNEF_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	BIOCARTA_HIVNEF_PATHWAY
Enrichment Score (ES)	-0.23054953
Normalized Enrichment Score (NES)	-1.1670203
Nominal p-value	0.29253113
FDR q-value	0.65176415
FWER p-Value	0.969

Fig 1: Enrichment plot: BIOCARTA_HIVNEF_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Map3k1	Map3k1	3673	0.386	-0.1167	No
2	Map3k5	Map3k5	4337	0.332	-0.1114	No
3	Rb1	Rb1	4551	0.315	-0.0887	No
4	Traf1	Traf1	4759	0.299	-0.0673	No
5	Fas	Fas	5290	0.262	-0.0633	No
6	Traf2	Traf2	5790	0.233	-0.0610	No
7	Casp7	Casp7	6275	0.208	-0.0605	No
8	Casp3	Casp3	6368	0.204	-0.0439	No
9	Map3k14	Map3k14	6501	0.197	-0.0296	No
10	Map2k7	Map2k7	6864	0.180	-0.0267	No
11	Cradd	Cradd	7025	0.172	-0.0162	No
12	Casp9	Casp9	7581	0.148	-0.0248	No
13	Gsn	Gsn	7619	0.146	-0.0117	No
14	Dffb	Dffb	7643	0.144	0.0019	No
15	Arhgdib	Arhgdib	8052	0.125	-0.0028	No
16	Mdm2	Mdm2	8497	0.107	-0.0108	No
17	Prkcd	Prkcd	8696	0.100	-0.0091	No
18	Cflar	Cflar	8965	0.090	-0.0114	No
19	Mapk8	Mapk8	9423	0.072	-0.0235	No
20	Xiap	Xiap	9622	0.063	-0.0255	No
21	Tnfrsf1a	Tnfrsf1a	9650	0.062	-0.0204	No
22	Sptan1	Sptan1	9735	0.059	-0.0180	No
23	Cycs	Cycs	10003	0.049	-0.0244	No
24	Tnfrsf1b	Tnfrsf1b	10080	0.046	-0.0230	No
25	Rasa1	Rasa1	10544	0.029	-0.0396	No
26	Birc2	Birc2	10690	0.024	-0.0433	No
27	Tradd	Tradd	10705	0.024	-0.0415	No
28	Pak2	Pak2	10747	0.023	-0.0410	No
29	Dffa	Dffa	10778	0.022	-0.0401	No
30	Daxx	Daxx	11741	-0.012	-0.0797	No
31	Casp2	Casp2	11888	-0.017	-0.0841	No
32	Chuk	Chuk	11940	-0.019	-0.0844	No
33	Ripk1	Ripk1	11972	-0.020	-0.0836	No
34	Nfkbia	Nfkbia	13066	-0.058	-0.1241	No
35	Actg1	Actg1	13840	-0.088	-0.1480	No
36	Lmnb2	Lmnb2	14055	-0.096	-0.1473	No
37	Nfkb1	Nfkb1	14105	-0.098	-0.1395	No
38	Bag4	Bag4	14463	-0.113	-0.1432	No
39	Parp1	Parp1	14523	-0.115	-0.1341	No
40	Psen1	Psen1	14715	-0.123	-0.1298	No
41	Lmna	Lmna	14952	-0.133	-0.1264	No
42	Rela	Rela	15079	-0.139	-0.1177	No
43	Fadd	Fadd	15265	-0.145	-0.1109	No
44	Psen2	Psen2	16149	-0.181	-0.1300	No
45	Cdk11b	Cdk11b	16391	-0.192	-0.1209	No
46	Casp6	Casp6	16805	-0.212	-0.1170	No
47	Lmnb1	Lmnb1	18732	-0.306	-0.1678	No
48	Apaf1	Apaf1	18877	-0.314	-0.1422	No
49	Casp8	Casp8	18989	-0.321	-0.1146	No
50	Prkdc	Prkdc	21727	-0.599	-0.1701	Yes
51	Tnf	Tnf	22375	-0.749	-0.1220	Yes
52	Bid	Bid	22447	-0.771	-0.0473	Yes
53	Bcl2	Bcl2	22909	-0.974	0.0314	Yes

Fig 2: BIOCARTA_HIVNEF_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_HIVNEF_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_HIVNEF_PATHWAY