Details for gene set BIOCARTA_IL1R_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	BIOCARTA_IL1R_PATHWAY
Enrichment Score (ES)	-0.35732225
Normalized Enrichment Score (NES)	-1.2889191
Nominal p-value	0.16766468
FDR q-value	0.5433464
FWER p-Value	0.909

Fig 1: Enrichment plot: BIOCARTA_IL1R_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Irak3	Irak3	2484	0.525	-0.0505	No
2	Jun	Jun	2502	0.522	0.0032	No
3	Map2k3	Map2k3	3009	0.450	0.0287	No
4	Mapk14	Mapk14	3143	0.436	0.0685	No
5	Map3k1	Map3k1	3673	0.386	0.0864	No
6	Il1a	Il1a	4352	0.331	0.0922	No
7	Traf6	Traf6	4692	0.303	0.1094	No
8	Map3k14	Map3k14	6501	0.197	0.0535	No
9	Il6	Il6	8669	0.101	-0.0278	No
10	Mapk8	Mapk8	9423	0.072	-0.0521	No
11	Map3k7	Map3k7	11042	0.013	-0.1193	No
12	Irak2	Irak2	11236	0.006	-0.1269	No
13	Ikbkb	Ikbkb	11654	-0.008	-0.1436	No
14	Chuk	Chuk	11940	-0.019	-0.1537	No
15	Nfkbia	Nfkbia	13066	-0.058	-0.1952	No
16	Nfkb1	Nfkb1	14105	-0.098	-0.2289	No
17	Rela	Rela	15079	-0.139	-0.2557	No
18	Tgfb1	Tgfb1	15196	-0.142	-0.2457	No
19	Myd88	Myd88	15736	-0.164	-0.2514	No
20	Il1r1	Il1r1	18238	-0.281	-0.3280	Yes
21	Irak1	Irak1	18277	-0.284	-0.3000	Yes
22	Il1rap	Il1rap	18295	-0.285	-0.2711	Yes
23	Il1rn	Il1rn	18845	-0.312	-0.2618	Yes
24	Ecsit	Ecsit	20237	-0.412	-0.2777	Yes
25	Tgfb2	Tgfb2	21223	-0.520	-0.2652	Yes
26	Il1b	Il1b	21929	-0.640	-0.2284	Yes
27	Tnf	Tnf	22375	-0.749	-0.1691	Yes
28	Map2k6	Map2k6	22945	-0.993	-0.0897	Yes
29	Tgfb3	Tgfb3	23137	-1.146	0.0217	Yes

Fig 2: BIOCARTA_IL1R_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IL1R_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IL1R_PATHWAY