Details for gene set BIOCARTA_NFAT_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	BIOCARTA_NFAT_PATHWAY
Enrichment Score (ES)	-0.37614757
Normalized Enrichment Score (NES)	-1.4318625
Nominal p-value	0.0989899
FDR q-value	0.311969
FWER p-Value	0.786

Fig 1: Enrichment plot: BIOCARTA_NFAT_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Acta1	Acta1	288	1.705	0.0694	No
2	Hand2	Hand2	534	1.303	0.1213	No
3	Akt1	Akt1	1613	0.701	0.1092	No
4	Pik3r1	Pik3r1	1878	0.634	0.1283	No
5	Ppp3cb	Ppp3cb	2234	0.573	0.1407	No
6	Mapk14	Mapk14	3143	0.436	0.1231	No
7	Fgf2	Fgf2	3550	0.398	0.1249	No
8	Crebbp	Crebbp	4144	0.347	0.1164	No
9	Mef2c	Mef2c	4263	0.337	0.1275	No
10	Agt	Agt	4496	0.320	0.1330	No
11	Pik3ca	Pik3ca	5000	0.282	0.1252	No
12	Prkacb	Prkacb	5110	0.275	0.1337	No
13	Ppp3ca	Ppp3ca	5298	0.262	0.1383	No
14	Raf1	Raf1	5546	0.246	0.1396	No
15	Mapk3	Mapk3	5607	0.243	0.1487	No
16	Gsk3b	Gsk3b	7312	0.159	0.0841	No
17	Map2k1	Map2k1	7527	0.150	0.0822	No
18	Rps6kb1	Rps6kb1	7783	0.137	0.0780	No
19	Nfatc3	Nfatc3	8091	0.124	0.0709	No
20	Mapk1	Mapk1	8711	0.099	0.0494	No
21	Csnk1a1	Csnk1a1	8851	0.094	0.0480	No
22	Mapk8	Mapk8	9423	0.072	0.0272	No
23	Hras	Hras	10115	0.045	0.0001	No
24	Calm3	Calm3	10304	0.039	-0.0060	No
25	Nkx2-5	Nkx2-5	10720	0.023	-0.0225	No
26	Calm1	Calm1	10783	0.021	-0.0241	No
27	Nfatc1	Nfatc1	11526	-0.005	-0.0553	No
28	Nfatc2	Nfatc2	13663	-0.080	-0.1419	No
29	Prkar2b	Prkar2b	14277	-0.106	-0.1628	No
30	Pik3cg	Pik3cg	14778	-0.126	-0.1780	No
31	Ppp3cc	Ppp3cc	16263	-0.186	-0.2320	No
32	Nfatc4	Nfatc4	16982	-0.221	-0.2518	No
33	Calr	Calr	18975	-0.320	-0.3209	No
34	Gata4	Gata4	19892	-0.383	-0.3413	No
35	Prkar2a	Prkar2a	20537	-0.442	-0.3475	No
36	Edn1	Edn1	21215	-0.519	-0.3513	Yes
37	Prkar1a	Prkar1a	21616	-0.579	-0.3406	Yes
38	Camk2a	Camk2a	22332	-0.738	-0.3356	Yes
39	Prkar1b	Prkar1b	22681	-0.865	-0.3089	Yes
40	Ctf1	Ctf1	22689	-0.868	-0.2677	Yes
41	Camk4	Camk4	22818	-0.926	-0.2288	Yes
42	Igf1	Igf1	22893	-0.967	-0.1857	Yes
43	Hand1	Hand1	23152	-1.152	-0.1415	Yes
44	Hbegf	Hbegf	23417	-1.537	-0.0792	Yes
45	Nppa	Nppa	23519	-1.860	0.0055	Yes

Fig 2: BIOCARTA_NFAT_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_NFAT_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_NFAT_PATHWAY