Details for gene set BIOCARTA_NTHI_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	BIOCARTA_NTHI_PATHWAY
Enrichment Score (ES)	-0.31975177
Normalized Enrichment Score (NES)	-1.2129073
Nominal p-value	0.186
FDR q-value	0.57878697
FWER p-Value	0.944

Fig 1: Enrichment plot: BIOCARTA_NTHI_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Tgfbr1	Tgfbr1	2901	0.462	-0.0481	No
2	Map2k3	Map2k3	3009	0.450	0.0202	No
3	Mapk14	Mapk14	3143	0.436	0.0850	No
4	Dusp1	Dusp1	4129	0.348	0.0995	No
5	Crebbp	Crebbp	4144	0.347	0.1549	No
6	Nr3c1	Nr3c1	4358	0.330	0.1992	No
7	Map3k14	Map3k14	6501	0.197	0.1405	No
8	Smad3	Smad3	8193	0.119	0.0882	No
9	Smad4	Smad4	8595	0.104	0.0880	No
10	Tgfbr2	Tgfbr2	9974	0.050	0.0378	No
11	Map3k7	Map3k7	11042	0.013	-0.0053	No
12	Ikbkb	Ikbkb	11654	-0.008	-0.0298	No
13	Chuk	Chuk	11940	-0.019	-0.0388	No
14	Ep300	Ep300	12226	-0.029	-0.0462	No
15	Nfkbia	Nfkbia	13066	-0.058	-0.0723	No
16	Nfkb1	Nfkb1	14105	-0.098	-0.1003	No
17	Rela	Rela	15079	-0.139	-0.1191	No
18	Myd88	Myd88	15736	-0.164	-0.1203	No
19	Mapk11	Mapk11	20449	-0.434	-0.2496	Yes
20	Il1b	Il1b	21929	-0.640	-0.2088	Yes
21	Tnf	Tnf	22375	-0.749	-0.1066	Yes
22	Map2k6	Map2k6	22945	-0.993	0.0298	Yes

Fig 2: BIOCARTA_NTHI_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_NTHI_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_NTHI_PATHWAY