Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO |
| Phenotype | KO_vs_WTandHET.cls#WT_versus_KO |
| Upregulated in class | KO |
| GeneSet | BIOCARTA_P53_PATHWAY |
| Enrichment Score (ES) | -0.5373281 |
| Normalized Enrichment Score (NES) | -1.4603702 |
| Nominal p-value | 0.07212476 |
| FDR q-value | 0.3146389 |
| FWER p-Value | 0.728 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | Gadd45a | Gadd45a | 914 | 0.971 | 0.0946 | No |
| 2 | Rb1 | Rb1 | 4551 | 0.315 | -0.0160 | No |
| 3 | Cdk2 | Cdk2 | 4769 | 0.298 | 0.0157 | No |
| 4 | Mdm2 | Mdm2 | 8497 | 0.107 | -0.1272 | No |
| 5 | Timp3 | Timp3 | 16786 | -0.211 | -0.4489 | No |
| 6 | Apaf1 | Apaf1 | 18877 | -0.314 | -0.4942 | Yes |
| 7 | Trp53 | Trp53 | 18947 | -0.319 | -0.4534 | Yes |
| 8 | Ccnd1 | Ccnd1 | 19677 | -0.368 | -0.4338 | Yes |
| 9 | Bax | Bax | 20028 | -0.394 | -0.3945 | Yes |
| 10 | Cdkn1a | Cdkn1a | 20276 | -0.417 | -0.3477 | Yes |
| 11 | Pcna | Pcna | 20324 | -0.421 | -0.2918 | Yes |
| 12 | Cdk4 | Cdk4 | 20534 | -0.442 | -0.2400 | Yes |
| 13 | E2f1 | E2f1 | 21369 | -0.542 | -0.2009 | Yes |
| 14 | Bcl2 | Bcl2 | 22909 | -0.974 | -0.1323 | Yes |
| 15 | Ccne1 | Ccne1 | 23202 | -1.192 | 0.0189 | Yes |
