Details for gene set BIOCARTA_PYK2_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	BIOCARTA_PYK2_PATHWAY
Enrichment Score (ES)	0.38062733
Normalized Enrichment Score (NES)	1.3262818
Nominal p-value	0.13409962
FDR q-value	0.5081016
FWER p-Value	0.904

Fig 1: Enrichment plot: BIOCARTA_PYK2_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Jun	Jun	2502	0.522	0.0120	Yes
2	Map2k3	Map2k3	3009	0.450	0.0922	Yes
3	Mapk14	Mapk14	3143	0.436	0.1850	Yes
4	Map3k1	Map3k1	3673	0.386	0.2498	Yes
5	Plcg1	Plcg1	5128	0.274	0.2501	Yes
6	Raf1	Raf1	5546	0.246	0.2880	Yes
7	Mapk3	Mapk3	5607	0.243	0.3403	Yes
8	Sos1	Sos1	6026	0.221	0.3724	Yes
9	Gnaq	Gnaq	7124	0.167	0.3638	Yes
10	Map2k1	Map2k1	7527	0.150	0.3806	Yes
11	Mapk1	Mapk1	8711	0.099	0.3529	No
12	Prkcb	Prkcb	8829	0.094	0.3693	No
13	Mapk8	Mapk8	9423	0.072	0.3604	No
14	Map2k4	Map2k4	9795	0.056	0.3575	No
15	Hras	Hras	10115	0.045	0.3541	No
16	Calm3	Calm3	10304	0.039	0.3549	No
17	Shc1	Shc1	10536	0.030	0.3518	No
18	Calm1	Calm1	10783	0.021	0.3462	No
19	Bcar1	Bcar1	11480	-0.003	0.3174	No
20	Grb2	Grb2	11511	-0.004	0.3170	No
21	Map2k2	Map2k2	12014	-0.021	0.3006	No
22	Crkl	Crkl	12505	-0.038	0.2885	No
23	Prkca	Prkca	16483	-0.197	0.1646	No
24	Pak1	Pak1	17621	-0.252	0.1733	No
25	Ptk2b	Ptk2b	19604	-0.362	0.1712	No

Fig 2: BIOCARTA_PYK2_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_PYK2_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_PYK2_PATHWAY