Details for gene set REACTOME_BASE_EXCISION_REPAIR[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	REACTOME_BASE_EXCISION_REPAIR
Enrichment Score (ES)	-0.64064044
Normalized Enrichment Score (NES)	-1.8054354
Nominal p-value	0.0
FDR q-value	0.16262497
FWER p-Value	0.4

Fig 1: Enrichment plot: REACTOME_BASE_EXCISION_REPAIR   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	H2az2	H2az2	3298	0.422	-0.1221	No
2	Neil1	Neil1	5694	0.238	-0.2136	No
3	Parg	Parg	7103	0.168	-0.2663	No
4	Parp2	Parp2	7751	0.139	-0.2879	No
5	Terf2ip	Terf2ip	8691	0.100	-0.3235	No
6	Mutyh	Mutyh	10606	0.027	-0.4034	No
7	H2bc21	H2bc21	10626	0.026	-0.4031	No
8	Terf1	Terf1	10651	0.026	-0.4031	No
9	Ogg1	Ogg1	10781	0.021	-0.4077	No
10	Terf2	Terf2	10857	0.019	-0.4100	No
11	Adprs	Adprs	11187	0.008	-0.4237	No
12	Smug1	Smug1	12013	-0.021	-0.4577	No
13	Nthl1	Nthl1	12031	-0.022	-0.4575	No
14	Acd	Acd	12041	-0.022	-0.4570	No
15	Rpa3	Rpa3	12241	-0.029	-0.4642	No
16	H2ax	H2ax	12602	-0.042	-0.4777	No
17	Pot1a	Pot1a	12830	-0.051	-0.4852	No
18	Rfc2	Rfc2	13247	-0.066	-0.5001	No
19	Rfc1	Rfc1	13270	-0.066	-0.4982	No
20	Polb	Polb	13275	-0.067	-0.4956	No
21	H2aj	H2aj	13418	-0.071	-0.4986	No
22	Xrcc1	Xrcc1	13637	-0.080	-0.5045	No
23	Pole3	Pole3	13712	-0.082	-0.5042	No
24	Pnkp	Pnkp	13949	-0.093	-0.5103	No
25	Rpa1	Rpa1	14023	-0.095	-0.5094	No
26	H2ac19	H2ac19	14094	-0.098	-0.5082	No
27	Parp1	Parp1	14523	-0.115	-0.5215	No
28	Pole4	Pole4	14930	-0.132	-0.5332	No
29	Lig3	Lig3	15120	-0.140	-0.5353	No
30	Pold4	Pold4	15395	-0.150	-0.5406	No
31	Neil3	Neil3	16002	-0.175	-0.5590	No
32	Pold3	Pold3	16273	-0.187	-0.5626	No
33	Mbd4	Mbd4	16308	-0.188	-0.5561	No
34	Pole2	Pole2	16365	-0.191	-0.5505	No
35	H4c3	H4c3	16991	-0.221	-0.5677	No
36	Tdg	Tdg	17871	-0.263	-0.5939	No
37	Rpa2	Rpa2	18494	-0.294	-0.6079	No
38	Pold1	Pold1	19145	-0.331	-0.6215	No
39	Fen1	Fen1	19433	-0.350	-0.6190	No
40	H2bc22	H2bc22	19944	-0.388	-0.6244	Yes
41	Lig1	Lig1	20043	-0.396	-0.6119	Yes
42	Rfc3	Rfc3	20047	-0.396	-0.5954	Yes
43	Pcna	Pcna	20324	-0.421	-0.5893	Yes
44	Apex1	Apex1	20543	-0.443	-0.5800	Yes
45	Rfc5	Rfc5	20606	-0.450	-0.5637	Yes
46	Pole	Pole	20661	-0.456	-0.5468	Yes
47	H4c4	H4c4	20799	-0.470	-0.5328	Yes
48	H4c14	H4c14	20944	-0.487	-0.5184	Yes
49	Mpg	Mpg	21870	-0.628	-0.5313	Yes
50	Pold2	Pold2	21950	-0.643	-0.5076	Yes
51	H2bc9	H2bc9	21990	-0.652	-0.4819	Yes
52	Neil2	Neil2	22469	-0.777	-0.4695	Yes
53	Ung	Ung	22523	-0.799	-0.4382	Yes
54	Rfc4	Rfc4	22548	-0.808	-0.4052	Yes
55	H2bc8	H2bc8	22616	-0.834	-0.3730	Yes
56	H4c11	H4c11	22862	-0.951	-0.3434	Yes
57	H4c8	H4c8	22866	-0.953	-0.3035	Yes
58	H4c9	H4c9	22911	-0.975	-0.2644	Yes
59	H2ac7	H2ac7	22957	-1.001	-0.2242	Yes
60	H2bc4	H2bc4	23076	-1.092	-0.1833	Yes
61	H2bc6	H2bc6	23434	-1.594	-0.1315	Yes
62	H2bc3	H2bc3	23451	-1.655	-0.0626	Yes
63	H2ac6	H2ac6	23459	-1.688	0.0081	Yes

Fig 2: REACTOME_BASE_EXCISION_REPAIR   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_BASE_EXCISION_REPAIR: Random ES distribution   
Gene set null distribution of ES for REACTOME_BASE_EXCISION_REPAIR