Details for gene set REACTOME_FOXO_MEDIATED_TRANSCRIPTION[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	REACTOME_FOXO_MEDIATED_TRANSCRIPTION
Enrichment Score (ES)	0.55635136
Normalized Enrichment Score (NES)	1.8496888
Nominal p-value	0.0
FDR q-value	0.29842913
FWER p-Value	0.32

Fig 1: Enrichment plot: REACTOME_FOXO_MEDIATED_TRANSCRIPTION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Foxo6	Foxo6	72	2.584	0.4192	Yes
2	Akt1	Akt1	1613	0.701	0.4685	Yes
3	Akt2	Akt2	1944	0.623	0.5564	Yes
4	Smad2	Smad2	5122	0.275	0.4668	No
5	Foxo3	Foxo3	6736	0.186	0.4289	No
6	Sirt1	Sirt1	6876	0.180	0.4524	No
7	Foxo4	Foxo4	7380	0.156	0.4566	No
8	Foxo1	Foxo1	7779	0.138	0.4623	No
9	Smad3	Smad3	8193	0.119	0.4643	No
10	Smad4	Smad4	8595	0.104	0.4643	No
11	Ywhaz	Ywhaz	9745	0.058	0.4252	No
12	Sirt3	Sirt3	9851	0.054	0.4296	No
13	Ywhab	Ywhab	10624	0.027	0.4013	No
14	Ep300	Ep300	12226	-0.029	0.3382	No
15	Atxn3	Atxn3	13372	-0.070	0.3012	No
16	Akt3	Akt3	13704	-0.082	0.3006	No
17	Ywhaq	Ywhaq	13911	-0.091	0.3067	No
18	Ywhag	Ywhag	16047	-0.177	0.2453	No
19	Kat2b	Kat2b	16724	-0.208	0.2507	No
20	Sfn	Sfn	17762	-0.259	0.2491	No

Fig 2: REACTOME_FOXO_MEDIATED_TRANSCRIPTION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_FOXO_MEDIATED_TRANSCRIPTION: Random ES distribution   
Gene set null distribution of ES for REACTOME_FOXO_MEDIATED_TRANSCRIPTION