Details for gene set REACTOME_HDACS_DEACETYLATE_HISTONES[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	REACTOME_HDACS_DEACETYLATE_HISTONES
Enrichment Score (ES)	-0.51057696
Normalized Enrichment Score (NES)	-1.7911004
Nominal p-value	0.0019762847
FDR q-value	0.12660041
FWER p-Value	0.438

Fig 1: Enrichment plot: REACTOME_HDACS_DEACETYLATE_HISTONES   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	H2ac25	H2ac25	1609	0.702	-0.0344	No
2	H2ac21	H2ac21	2217	0.577	-0.0324	No
3	Sap30l	Sap30l	2379	0.545	-0.0130	No
4	Sap30	Sap30	2646	0.499	-0.0003	No
5	Chd4	Chd4	2989	0.453	0.0070	No
6	Tbl1xr1	Tbl1xr1	3002	0.451	0.0282	No
7	Gps2	Gps2	5055	0.278	-0.0454	No
8	Hdac1	Hdac1	5226	0.267	-0.0397	No
9	Suds3	Suds3	5437	0.253	-0.0364	No
10	Gatad2b	Gatad2b	5609	0.243	-0.0320	No
11	Rest	Rest	6445	0.200	-0.0578	No
12	Mta1	Mta1	6471	0.199	-0.0492	No
13	Rcor1	Rcor1	6756	0.185	-0.0524	No
14	Arid4a	Arid4a	6906	0.178	-0.0501	No
15	Gatad2a	Gatad2a	7307	0.160	-0.0594	No
16	Arid4b	Arid4b	7342	0.158	-0.0533	No
17	Phf21a	Phf21a	8230	0.118	-0.0852	No
18	H2bc21	H2bc21	10626	0.026	-0.1854	No
19	Rbbp7	Rbbp7	10693	0.024	-0.1870	No
20	Tbl1x	Tbl1x	10887	0.018	-0.1943	No
21	Hdac10	Hdac10	11669	-0.009	-0.2270	No
22	Mbd3	Mbd3	12454	-0.037	-0.2585	No
23	Hdac8	Hdac8	12557	-0.040	-0.2608	No
24	Hmg20b	Hmg20b	12672	-0.045	-0.2635	No
25	Hdac3	Hdac3	12812	-0.050	-0.2670	No
26	Mta3	Mta3	13241	-0.065	-0.2820	No
27	H2aj	H2aj	13418	-0.071	-0.2860	No
28	Mta2	Mta2	13729	-0.083	-0.2952	No
29	Rbbp4	Rbbp4	13929	-0.092	-0.2992	No
30	H3c8	H3c8	14068	-0.097	-0.3004	No
31	H2ac19	H2ac19	14094	-0.098	-0.2967	No
32	Chd3	Chd3	14962	-0.133	-0.3271	No
33	Kdm1a	Kdm1a	15563	-0.156	-0.3450	No
34	H4c3	H4c3	16991	-0.221	-0.3948	No
35	Ncor2	Ncor2	17087	-0.225	-0.3880	No
36	H2bc22	H2bc22	19944	-0.388	-0.4904	Yes
37	H3c15	H3c15	20319	-0.421	-0.4860	Yes
38	H4c4	H4c4	20799	-0.470	-0.4836	Yes
39	H4c14	H4c14	20944	-0.487	-0.4663	Yes
40	H2bc9	H2bc9	21990	-0.652	-0.4792	Yes
41	H3c4	H3c4	22083	-0.675	-0.4507	Yes
42	H2bc8	H2bc8	22616	-0.834	-0.4331	Yes
43	H4c11	H4c11	22862	-0.951	-0.3978	Yes
44	H4c8	H4c8	22866	-0.953	-0.3520	Yes
45	H4c9	H4c9	22911	-0.975	-0.3070	Yes
46	H2ac7	H2ac7	22957	-1.001	-0.2608	Yes
47	H2bc4	H2bc4	23076	-1.092	-0.2133	Yes
48	H2bc6	H2bc6	23434	-1.594	-0.1517	Yes
49	H2bc3	H2bc3	23451	-1.655	-0.0728	Yes
50	H2ac6	H2ac6	23459	-1.688	0.0081	Yes

Fig 2: REACTOME_HDACS_DEACETYLATE_HISTONES   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_HDACS_DEACETYLATE_HISTONES: Random ES distribution   
Gene set null distribution of ES for REACTOME_HDACS_DEACETYLATE_HISTONES