Details for gene set REACTOME_INOSITOL_PHOSPHATE_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	REACTOME_INOSITOL_PHOSPHATE_METABOLISM
Enrichment Score (ES)	0.5106334
Normalized Enrichment Score (NES)	1.6995561
Nominal p-value	0.012269938
FDR q-value	0.37860212
FWER p-Value	0.661

Fig 1: Enrichment plot: REACTOME_INOSITOL_PHOSPHATE_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Nudt11	Nudt11	318	1.631	0.0914	Yes
2	Ip6k3	Ip6k3	491	1.352	0.1711	Yes
3	Nudt10	Nudt10	711	1.124	0.2341	Yes
4	Nudt4	Nudt4	1091	0.876	0.2744	Yes
5	Impa2	Impa2	1161	0.843	0.3257	Yes
6	Inppl1	Inppl1	1200	0.830	0.3774	Yes
7	Plcg2	Plcg2	1565	0.712	0.4078	Yes
8	Inpp4b	Inpp4b	2278	0.566	0.4141	Yes
9	Itpka	Itpka	2470	0.527	0.4398	Yes
10	Isyna1	Isyna1	2929	0.459	0.4499	Yes
11	Plcd3	Plcd3	3336	0.418	0.4596	Yes
12	Plcd1	Plcd1	4230	0.339	0.4436	Yes
13	Plcb2	Plcb2	4236	0.339	0.4651	Yes
14	Nudt3	Nudt3	4440	0.325	0.4774	Yes
15	Calm2	Calm2	4510	0.319	0.4950	Yes
16	Ip6k1	Ip6k1	4612	0.310	0.5106	Yes
17	Plcg1	Plcg1	5128	0.274	0.5064	No
18	Ip6k2	Ip6k2	7873	0.133	0.3988	No
19	Ipmk	Ipmk	8219	0.118	0.3918	No
20	Ippk	Ippk	8303	0.115	0.3956	No
21	Ppip5k2	Ppip5k2	8368	0.113	0.4002	No
22	Ocrl	Ocrl	9257	0.079	0.3676	No
23	Plcb4	Plcb4	9302	0.077	0.3707	No
24	Itpkb	Itpkb	9427	0.072	0.3700	No
25	Inpp5b	Inpp5b	9456	0.071	0.3734	No
26	Calm3	Calm3	10304	0.039	0.3400	No
27	Plcb3	Plcb3	10477	0.032	0.3348	No
28	Pld4	Pld4	10732	0.023	0.3255	No
29	Calm1	Calm1	10783	0.021	0.3247	No
30	Inpp4a	Inpp4a	10785	0.021	0.3261	No
31	Synj1	Synj1	10863	0.019	0.3240	No
32	Impa1	Impa1	11261	0.005	0.3075	No
33	Pten	Pten	12340	-0.032	0.2639	No
34	Minpp1	Minpp1	12655	-0.044	0.2535	No
35	Inpp1	Inpp1	13830	-0.087	0.2093	No
36	Inpp5d	Inpp5d	15173	-0.142	0.1616	No
37	Plcb1	Plcb1	15540	-0.156	0.1561	No
38	Itpkc	Itpkc	15630	-0.160	0.1626	No
39	Plch1	Plch1	16610	-0.203	0.1342	No
40	Ppip5k1	Ppip5k1	16720	-0.208	0.1430	No
41	Itpk1	Itpk1	17650	-0.253	0.1199	No
42	Plce1	Plce1	17804	-0.261	0.1302	No
43	Plch2	Plch2	19269	-0.338	0.0899	No
44	Inpp5a	Inpp5a	21619	-0.579	0.0277	No
45	Inpp5j	Inpp5j	22770	-0.906	0.0372	No

Fig 2: REACTOME_INOSITOL_PHOSPHATE_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_INOSITOL_PHOSPHATE_METABOLISM: Random ES distribution   
Gene set null distribution of ES for REACTOME_INOSITOL_PHOSPHATE_METABOLISM