Details for gene set REACTOME_PYRUVATE

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	REACTOME_PYRUVATE_METABOLISM
Enrichment Score (ES)	0.50101024
Normalized Enrichment Score (NES)	1.7985722
Nominal p-value	0.004016064
FDR q-value	0.30796495
FWER p-Value	0.456

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Me3	Me3	197	1.955	0.0918	Yes
2	Gpt	Gpt	238	1.825	0.1836	Yes
3	Ldha	Ldha	504	1.337	0.2409	Yes
4	Hagh	Hagh	1384	0.765	0.2428	Yes
5	Ldhb	Ldhb	1445	0.745	0.2784	Yes
6	Pdha1	Pdha1	1572	0.711	0.3095	Yes
7	Pdk4	Pdk4	1669	0.686	0.3406	Yes
8	Uba52	Uba52	2497	0.523	0.3323	Yes
9	Fahd1	Fahd1	2605	0.506	0.3537	Yes
10	Maea	Maea	2898	0.463	0.3650	Yes
11	Pdpr	Pdpr	3232	0.428	0.3728	Yes
12	Rmnd5a	Rmnd5a	3239	0.427	0.3945	Yes
13	Pdk1	Pdk1	3361	0.416	0.4106	Yes
14	Dld	Dld	3822	0.373	0.4102	Yes
15	Gid8	Gid8	4171	0.345	0.4132	Yes
16	Pdp2	Pdp2	4227	0.339	0.4282	Yes
17	Sirt4	Sirt4	4258	0.338	0.4442	Yes
18	Wdr26	Wdr26	4276	0.336	0.4607	Yes
19	Pdhx	Pdhx	4292	0.335	0.4772	Yes
20	Pdk2	Pdk2	4301	0.334	0.4940	Yes
21	Gid4	Gid4	4522	0.318	0.5009	Yes
22	Nek1	Nek1	4872	0.290	0.5010	Yes
23	Ubb	Ubb	6345	0.205	0.4491	No
24	Dlat	Dlat	6354	0.204	0.4593	No
25	Vdac1	Vdac1	6786	0.183	0.4504	No
26	Ubc	Ubc	6804	0.183	0.4591	No
27	Mkln1	Mkln1	7087	0.169	0.4558	No
28	Uba52rt	Uba52rt	8363	0.113	0.4075	No
29	Ranbp9	Ranbp9	9069	0.086	0.3821	No
30	Armc8	Armc8	10712	0.024	0.3137	No
31	Rmnd5b	Rmnd5b	11414	-0.000	0.2840	No
32	Pgam5	Pgam5	13582	-0.078	0.1962	No
33	Pkm	Pkm	13591	-0.078	0.1999	No
34	Glo1	Glo1	13599	-0.078	0.2036	No
35	Pdhb	Pdhb	13976	-0.094	0.1925	No
36	Rps27a	Rps27a	15542	-0.156	0.1341	No
37	Gstz1	Gstz1	17240	-0.233	0.0742	No
38	Pcx	Pcx	18818	-0.311	0.0233	No
39	Me1	Me1	19533	-0.357	0.0114	No
40	Ldhal6b	Ldhal6b	20837	-0.475	-0.0195	No
41	Me2	Me2	21093	-0.504	-0.0044	No
42	Pdp1	Pdp1	22100	-0.679	-0.0123	No
43	Pdk3	Pdk3	23408	-1.520	0.0102	No