Details for gene set REACTOME_SIGNALING_BY_FGFR1[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	REACTOME_SIGNALING_BY_FGFR1
Enrichment Score (ES)	0.45473546
Normalized Enrichment Score (NES)	1.6355888
Nominal p-value	0.021526419
FDR q-value	0.36544898
FWER p-Value	0.787

Fig 1: Enrichment plot: REACTOME_SIGNALING_BY_FGFR1   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Fgf18	Fgf18	400	1.474	0.0812	Yes
2	Fgf6	Fgf6	465	1.380	0.1704	Yes
3	Flrt1	Flrt1	560	1.274	0.2512	Yes
4	Tgfbr3	Tgfbr3	1014	0.915	0.2930	Yes
5	Frs3	Frs3	1523	0.724	0.3197	Yes
6	Fgfrl1	Fgfrl1	1801	0.653	0.3514	Yes
7	Pik3r1	Pik3r1	1878	0.634	0.3905	Yes
8	Kl	Kl	2208	0.578	0.4150	Yes
9	Uba52	Uba52	2497	0.523	0.4376	Yes
10	Fgf2	Fgf2	3550	0.398	0.4196	Yes
11	Frs2	Frs2	4137	0.347	0.4179	Yes
12	Pik3ca	Pik3ca	5000	0.282	0.4001	Yes
13	Plcg1	Plcg1	5128	0.274	0.4130	Yes
14	Fgf1	Fgf1	5296	0.262	0.4234	Yes
15	Mapk3	Mapk3	5607	0.243	0.4264	Yes
16	Spry2	Spry2	5668	0.240	0.4399	Yes
17	Sos1	Sos1	6026	0.221	0.4394	Yes
18	Ubb	Ubb	6345	0.205	0.4396	Yes
19	Flrt2	Flrt2	6570	0.194	0.4431	Yes
20	Ubc	Ubc	6804	0.183	0.4454	Yes
21	Gab1	Gab1	6867	0.180	0.4547	Yes
22	Mknk1	Mknk1	7745	0.139	0.4268	No
23	Uba52rt	Uba52rt	8363	0.113	0.4082	No
24	Mapk1	Mapk1	8711	0.099	0.4001	No
25	Ppp2r1a	Ppp2r1a	9500	0.069	0.3713	No
26	Fgf9	Fgf9	9704	0.060	0.3667	No
27	Hras	Hras	10115	0.045	0.3524	No
28	Shc1	Shc1	10536	0.030	0.3366	No
29	Ptpn11	Ptpn11	11110	0.010	0.3130	No
30	Grb2	Grb2	11511	-0.004	0.2963	No
31	Kras	Kras	11764	-0.013	0.2864	No
32	Braf	Braf	12225	-0.029	0.2689	No
33	Ppp2ca	Ppp2ca	13141	-0.061	0.2342	No
34	Ppp2cb	Ppp2cb	13211	-0.064	0.2355	No
35	Gipc1	Gipc1	14499	-0.115	0.1886	No
36	Fgf10	Fgf10	14622	-0.119	0.1914	No
37	Rps27a	Rps27a	15542	-0.156	0.1628	No
38	Spred2	Spred2	16567	-0.201	0.1328	No
39	Spred1	Spred1	16713	-0.207	0.1405	No
40	Fgfr1	Fgfr1	18385	-0.288	0.0889	No
41	Flrt3	Flrt3	20547	-0.444	0.0269	No
42	Cbl	Cbl	20919	-0.485	0.0435	No
43	Src	Src	21110	-0.507	0.0692	No
44	Fgf17	Fgf17	21584	-0.575	0.0875	No

Fig 2: REACTOME_SIGNALING_BY_FGFR1   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_SIGNALING_BY_FGFR1: Random ES distribution   
Gene set null distribution of ES for REACTOME_SIGNALING_BY_FGFR1