Details for gene set REACTOME_TELOMERE_MAINTENANCE[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	REACTOME_TELOMERE_MAINTENANCE
Enrichment Score (ES)	-0.57417023
Normalized Enrichment Score (NES)	-1.7969278
Nominal p-value	0.0
FDR q-value	0.13833912
FWER p-Value	0.426

Fig 1: Enrichment plot: REACTOME_TELOMERE_MAINTENANCE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ten1	Ten1	2165	0.583	-0.0710	No
2	H2az2	H2az2	3298	0.422	-0.1039	No
3	Ppp6r3	Ppp6r3	3493	0.403	-0.0977	No
4	Cdk2	Cdk2	4769	0.298	-0.1411	No
5	Chtf8	Chtf8	5035	0.280	-0.1423	No
6	H3f3a	H3f3a	5518	0.247	-0.1539	No
7	Tert	Tert	5888	0.228	-0.1614	No
8	Ppp6c	Ppp6c	6218	0.212	-0.1678	No
9	Atrx	Atrx	6341	0.205	-0.1657	No
10	Ankrd28	Ankrd28	7174	0.165	-0.1950	No
11	H3f3b	H3f3b	7766	0.138	-0.2152	No
12	Terf2ip	Terf2ip	8691	0.100	-0.2508	No
13	Pif1	Pif1	9100	0.084	-0.2651	No
14	H2bc21	H2bc21	10626	0.026	-0.3288	No
15	Terf1	Terf1	10651	0.026	-0.3289	No
16	Terf2	Terf2	10857	0.019	-0.3369	No
17	Daxx	Daxx	11741	-0.012	-0.3739	No
18	Pola2	Pola2	11775	-0.013	-0.3749	No
19	Rtel1	Rtel1	11911	-0.018	-0.3800	No
20	Acd	Acd	12041	-0.022	-0.3846	No
21	Rpa3	Rpa3	12241	-0.029	-0.3920	No
22	H2ax	H2ax	12602	-0.042	-0.4058	No
23	Pot1a	Pot1a	12830	-0.051	-0.4136	No
24	Rfc2	Rfc2	13247	-0.066	-0.4289	No
25	Rfc1	Rfc1	13270	-0.066	-0.4275	No
26	H2aj	H2aj	13418	-0.071	-0.4312	No
27	Rpa1	Rpa1	14023	-0.095	-0.4534	No
28	H2ac19	H2ac19	14094	-0.098	-0.4528	No
29	Ccna1	Ccna1	14516	-0.115	-0.4666	No
30	Pold4	Pold4	15395	-0.150	-0.4984	No
31	Ctc1	Ctc1	15895	-0.171	-0.5135	No
32	Pold3	Pold3	16273	-0.187	-0.5228	No
33	Wrap53	Wrap53	16298	-0.188	-0.5171	No
34	Nop10	Nop10	16884	-0.215	-0.5342	No
35	H4c3	H4c3	16991	-0.221	-0.5308	No
36	Shq1	Shq1	17163	-0.229	-0.5299	No
37	Wrn	Wrn	17358	-0.238	-0.5296	No
38	Ccna2	Ccna2	17693	-0.255	-0.5346	No
39	Dkc1	Dkc1	17984	-0.269	-0.5373	No
40	Rpa2	Rpa2	18494	-0.294	-0.5484	No
41	Stn1	Stn1	18859	-0.313	-0.5526	No
42	Pold1	Pold1	19145	-0.331	-0.5529	No
43	Fen1	Fen1	19433	-0.350	-0.5525	No
44	H2bc22	H2bc22	19944	-0.388	-0.5603	Yes
45	Lig1	Lig1	20043	-0.396	-0.5503	Yes
46	Gar1	Gar1	20045	-0.396	-0.5362	Yes
47	Rfc3	Rfc3	20047	-0.396	-0.5221	Yes
48	Prim2	Prim2	20082	-0.399	-0.5092	Yes
49	Pcna	Pcna	20324	-0.421	-0.5044	Yes
50	Dna2	Dna2	20542	-0.443	-0.4977	Yes
51	Prim1	Prim1	20566	-0.446	-0.4827	Yes
52	Rfc5	Rfc5	20606	-0.450	-0.4683	Yes
53	Blm	Blm	20616	-0.451	-0.4525	Yes
54	H4c4	H4c4	20799	-0.470	-0.4434	Yes
55	H4c14	H4c14	20944	-0.487	-0.4321	Yes
56	Pola1	Pola1	20956	-0.488	-0.4151	Yes
57	Chtf18	Chtf18	21679	-0.592	-0.4246	Yes
58	Pold2	Pold2	21950	-0.643	-0.4130	Yes
59	H2bc9	H2bc9	21990	-0.652	-0.3914	Yes
60	Nhp2	Nhp2	22021	-0.659	-0.3691	Yes
61	Dscc1	Dscc1	22132	-0.685	-0.3492	Yes
62	Rfc4	Rfc4	22548	-0.808	-0.3379	Yes
63	H2bc8	H2bc8	22616	-0.834	-0.3110	Yes
64	H4c11	H4c11	22862	-0.951	-0.2873	Yes
65	H4c8	H4c8	22866	-0.953	-0.2534	Yes
66	H4c9	H4c9	22911	-0.975	-0.2203	Yes
67	H2ac7	H2ac7	22957	-1.001	-0.1865	Yes
68	H2bc4	H2bc4	23076	-1.092	-0.1524	Yes
69	H2bc6	H2bc6	23434	-1.594	-0.1105	Yes
70	H2bc3	H2bc3	23451	-1.655	-0.0520	Yes
71	H2ac6	H2ac6	23459	-1.688	0.0081	Yes

Fig 2: REACTOME_TELOMERE_MAINTENANCE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_TELOMERE_MAINTENANCE: Random ES distribution   
Gene set null distribution of ES for REACTOME_TELOMERE_MAINTENANCE