Details for gene set REACTOME_TIE2_SIGNALING[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	REACTOME_TIE2_SIGNALING
Enrichment Score (ES)	0.6443659
Normalized Enrichment Score (NES)	1.698254
Nominal p-value	0.002020202
FDR q-value	0.34750226
FWER p-Value	0.663

Fig 1: Enrichment plot: REACTOME_TIE2_SIGNALING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Angpt1	Angpt1	277	1.733	0.3009	Yes
2	Grb14	Grb14	442	1.415	0.5492	Yes
3	Pik3r1	Pik3r1	1878	0.634	0.6030	Yes
4	Pik3r2	Pik3r2	4184	0.343	0.5674	Yes
5	Tek	Tek	4277	0.336	0.6241	Yes
6	Pik3ca	Pik3ca	5000	0.282	0.6444	Yes
7	Sos1	Sos1	6026	0.221	0.6408	No
8	Pik3cb	Pik3cb	8798	0.095	0.5408	No
9	Hras	Hras	10115	0.045	0.4932	No
10	Dok2	Dok2	10279	0.039	0.4934	No
11	Shc1	Shc1	10536	0.030	0.4880	No
12	Ptpn11	Ptpn11	11110	0.010	0.4656	No
13	Angpt2	Angpt2	11449	-0.002	0.4516	No
14	Grb2	Grb2	11511	-0.004	0.4497	No
15	Kras	Kras	11764	-0.013	0.4413	No
16	Grb7	Grb7	19308	-0.341	0.1837	No

Fig 2: REACTOME_TIE2_SIGNALING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_TIE2_SIGNALING: Random ES distribution   
Gene set null distribution of ES for REACTOME_TIE2_SIGNALING