Details for gene set WP_ERBB_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	WP_ERBB_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.37203944
Normalized Enrichment Score (NES)	-1.3042233
Nominal p-value	0.14145383
FDR q-value	0.58538437
FWER p-Value	0.923

Fig 1: Enrichment plot: WP_ERBB_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Egf	Egf	213	1.913	0.0919	No
2	Nrg2	Nrg2	563	1.271	0.1441	No
3	Erbb4	Erbb4	676	1.149	0.2000	No
4	Jun	Jun	2502	0.522	0.1502	No
5	Cdkn1b	Cdkn1b	3591	0.394	0.1249	No
6	Mtor	Mtor	4779	0.298	0.0903	No
7	Araf	Araf	5027	0.280	0.0946	No
8	Plcg1	Plcg1	5128	0.274	0.1048	No
9	Sos1	Sos1	6026	0.221	0.0785	No
10	Map2k7	Map2k7	6864	0.180	0.0525	No
11	Gab1	Gab1	6867	0.180	0.0620	No
12	Gsk3b	Gsk3b	7312	0.159	0.0516	No
13	Map2k1	Map2k1	7527	0.150	0.0504	No
14	Abl1	Abl1	8455	0.109	0.0169	No
15	Mapk1	Mapk1	8711	0.099	0.0113	No
16	Elk1	Elk1	9008	0.088	0.0034	No
17	Mapk8	Mapk8	9423	0.072	-0.0103	No
18	Hras	Hras	10115	0.045	-0.0372	No
19	Grb2	Grb2	11511	-0.004	-0.0961	No
20	Shc2	Shc2	11578	-0.006	-0.0986	No
21	Nck1	Nck1	12044	-0.022	-0.1171	No
22	Erbb2	Erbb2	12556	-0.040	-0.1367	No
23	Tgfa	Tgfa	12770	-0.048	-0.1431	No
24	Eif4ebp1	Eif4ebp1	13215	-0.064	-0.1586	No
25	Bad	Bad	13461	-0.073	-0.1651	No
26	Pak4	Pak4	13579	-0.078	-0.1659	No
27	Akt3	Akt3	13704	-0.082	-0.1669	No
28	Egfr	Egfr	14996	-0.135	-0.2144	No
29	Ptk2	Ptk2	15103	-0.140	-0.2116	No
30	Prkca	Prkca	16483	-0.197	-0.2596	No
31	Crk	Crk	18182	-0.278	-0.3169	No
32	Areg	Areg	18239	-0.281	-0.3044	No
33	Ereg	Ereg	19466	-0.352	-0.3378	No
34	Cdkn1a	Cdkn1a	20276	-0.417	-0.3500	Yes
35	Cblc	Cblc	20536	-0.442	-0.3377	Yes
36	Nrg4	Nrg4	20762	-0.468	-0.3226	Yes
37	Erbb3	Erbb3	20878	-0.480	-0.3021	Yes
38	Src	Src	21110	-0.507	-0.2851	Yes
39	Stat5a	Stat5a	21349	-0.540	-0.2668	Yes
40	Pik3r5	Pik3r5	21814	-0.615	-0.2540	Yes
41	Camk2a	Camk2a	22332	-0.738	-0.2369	Yes
42	Myc	Myc	22951	-0.997	-0.2105	Yes
43	Nrg1	Nrg1	23223	-1.217	-0.1578	Yes
44	Hbegf	Hbegf	23417	-1.537	-0.0849	Yes
45	Btc	Btc	23495	-1.795	0.0065	Yes

Fig 2: WP_ERBB_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_ERBB_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for WP_ERBB_SIGNALING_PATHWAY