Details for gene set WP_GPCRS_NONODORANT[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	WP_GPCRS_NONODORANT
Enrichment Score (ES)	0.39762726
Normalized Enrichment Score (NES)	1.4555424
Nominal p-value	0.0020325202
FDR q-value	0.41789308
FWER p-Value	0.775

Fig 1: Enrichment plot: WP_GPCRS_NONODORANT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Adora1	Adora1	83	2.530	0.0292	Yes
2	Mas1	Mas1	143	2.184	0.0550	Yes
3	Ackr1	Ackr1	185	2.004	0.0792	Yes
4	Oprd1	Oprd1	198	1.952	0.1040	Yes
5	Grm1	Grm1	204	1.937	0.1289	Yes
6	Adra1a	Adra1a	259	1.779	0.1496	Yes
7	Gcgr	Gcgr	285	1.712	0.1707	Yes
8	Lpar3	Lpar3	368	1.539	0.1872	Yes
9	Celsr1	Celsr1	468	1.375	0.2008	Yes
10	Fzd2	Fzd2	484	1.356	0.2177	Yes
11	Adra1d	Adra1d	509	1.330	0.2339	Yes
12	Avpr1a	Avpr1a	564	1.271	0.2481	Yes
13	Adra2b	Adra2b	627	1.195	0.2609	Yes
14	Pth1r	Pth1r	685	1.142	0.2733	Yes
15	Sstr3	Sstr3	789	1.055	0.2826	Yes
16	Cxcr5	Cxcr5	874	1.004	0.2920	Yes
17	Glp1r	Glp1r	1052	0.898	0.2961	Yes
18	Adrb1	Adrb1	1073	0.883	0.3067	Yes
19	Ffar2	Ffar2	1110	0.864	0.3163	Yes
20	P2ry2	P2ry2	1239	0.812	0.3214	Yes
21	Fzd9	Fzd9	1258	0.807	0.3311	Yes
22	Fzd3	Fzd3	1449	0.745	0.3327	Yes
23	Adgrg2	Adgrg2	1510	0.728	0.3395	Yes
24	Opn3	Opn3	1790	0.656	0.3362	Yes
25	Fzd6	Fzd6	1943	0.623	0.3378	Yes
26	S1pr1	S1pr1	1958	0.619	0.3452	Yes
27	Fzd8	Fzd8	1993	0.612	0.3517	Yes
28	Vipr2	Vipr2	2053	0.602	0.3569	Yes
29	Uts2r	Uts2r	2061	0.600	0.3644	Yes
30	Agtr2	Agtr2	2111	0.594	0.3700	Yes
31	P2ry14	P2ry14	2174	0.582	0.3749	Yes
32	Adora2b	Adora2b	2462	0.528	0.3695	Yes
33	P2ry1	P2ry1	2482	0.525	0.3755	Yes
34	Hrh1	Hrh1	2681	0.494	0.3735	Yes
35	Celsr2	Celsr2	2707	0.490	0.3788	Yes
36	Bdkrb2	Bdkrb2	2789	0.479	0.3816	Yes
37	Ccrl2	Ccrl2	3024	0.449	0.3774	Yes
38	Gpr174	Gpr174	3052	0.446	0.3820	Yes
39	Hrh2	Hrh2	3053	0.446	0.3878	Yes
40	Prokr1	Prokr1	3118	0.439	0.3908	Yes
41	Opn4	Opn4	3166	0.434	0.3944	Yes
42	Ptafr	Ptafr	3231	0.428	0.3972	Yes
43	Npy1r	Npy1r	3349	0.417	0.3976	Yes
44	Ackr2	Ackr2	3568	0.396	0.3935	No
45	Adra1b	Adra1b	3642	0.389	0.3954	No
46	Lpar4	Lpar4	3722	0.382	0.3970	No
47	Ednra	Ednra	4700	0.303	0.3593	No
48	Lpar1	Lpar1	4714	0.302	0.3627	No
49	Agtr1b	Agtr1b	4747	0.300	0.3652	No
50	Adora2a	Adora2a	4959	0.285	0.3599	No
51	Gpr18	Gpr18	5210	0.269	0.3528	No
52	C5ar1	C5ar1	5216	0.268	0.3560	No
53	Oxtr	Oxtr	5552	0.246	0.3450	No
54	Mc5r	Mc5r	5691	0.238	0.3422	No
55	Gper1	Gper1	5776	0.233	0.3416	No
56	Gpr50	Gpr50	5868	0.229	0.3407	No
57	Gabbr2	Gabbr2	6182	0.213	0.3302	No
58	Nmbr	Nmbr	6441	0.201	0.3218	No
59	Adrb2	Adrb2	6732	0.186	0.3118	No
60	Cnr2	Cnr2	6972	0.174	0.3039	No
61	C3ar1	C3ar1	7058	0.170	0.3025	No
62	Lpar6	Lpar6	7262	0.161	0.2960	No
63	Adgrb3	Adgrb3	7444	0.153	0.2902	No
64	Adora3	Adora3	7506	0.151	0.2896	No
65	Ackr3	Ackr3	7560	0.149	0.2893	No
66	Ccr3	Ccr3	7589	0.147	0.2900	No
67	Calcrl	Calcrl	7630	0.145	0.2902	No
68	Adgrl4	Adgrl4	7786	0.137	0.2853	No
69	Aplnr	Aplnr	7975	0.129	0.2790	No
70	Grm3	Grm3	8063	0.124	0.2769	No
71	Rxfp3	Rxfp3	9022	0.088	0.2373	No
72	P2ry10	P2ry10	9292	0.077	0.2268	No
73	Adgrl3	Adgrl3	9444	0.071	0.2213	No
74	Adgre1	Adgre1	9749	0.058	0.2091	No
75	Gabbr1	Gabbr1	9810	0.056	0.2073	No
76	Adgrg1	Adgrg1	9970	0.050	0.2012	No
77	Grm8	Grm8	10571	0.028	0.1760	No
78	Adgrl2	Adgrl2	10579	0.028	0.1761	No
79	S1pr3	S1pr3	11013	0.014	0.1578	No
80	Drd2	Drd2	11310	0.003	0.1453	No
81	Drd1	Drd1	11660	-0.009	0.1306	No
82	P2ry12	P2ry12	11918	-0.018	0.1199	No
83	Cxcr3	Cxcr3	12624	-0.043	0.0904	No
84	Agtr1a	Agtr1a	13017	-0.057	0.0745	No
85	Fzd5	Fzd5	13174	-0.062	0.0686	No
86	Oxgr1	Oxgr1	13255	-0.066	0.0661	No
87	Cxcr4	Cxcr4	13301	-0.067	0.0650	No
88	Ccr1	Ccr1	13346	-0.069	0.0640	No
89	Glp2r	Glp2r	13451	-0.073	0.0606	No
90	S1pr5	S1pr5	13456	-0.073	0.0613	No
91	F2r	F2r	13462	-0.073	0.0621	No
92	Gprc5b	Gprc5b	13672	-0.081	0.0542	No
93	Gpr132	Gpr132	13889	-0.090	0.0462	No
94	Lpar5	Lpar5	13926	-0.092	0.0459	No
95	Ccr9	Ccr9	14443	-0.112	0.0253	No
96	Cnr1	Cnr1	14520	-0.115	0.0236	No
97	Fzd1	Fzd1	14752	-0.125	0.0154	No
98	Cysltr1	Cysltr1	14904	-0.131	0.0107	No
99	Sstr4	Sstr4	14969	-0.134	0.0097	No
100	Ptger1	Ptger1	15086	-0.139	0.0065	No
101	Smo	Smo	15172	-0.142	0.0048	No
102	Chrm3	Chrm3	15176	-0.142	0.0065	No
103	P2ry6	P2ry6	15346	-0.148	0.0012	No
104	Ptger3	Ptger3	15435	-0.151	-0.0006	No
105	Adgrl1	Adgrl1	15650	-0.161	-0.0076	No
106	Fzd4	Fzd4	15772	-0.166	-0.0106	No
107	Adgrb2	Adgrb2	15786	-0.166	-0.0090	No
108	Prokr2	Prokr2	15869	-0.170	-0.0103	No
109	Adra2a	Adra2a	16022	-0.176	-0.0145	No
110	Fzd7	Fzd7	16029	-0.176	-0.0125	No
111	C5ar2	C5ar2	16292	-0.187	-0.0212	No
112	Ccr7	Ccr7	16310	-0.188	-0.0195	No
113	Htr7	Htr7	16489	-0.197	-0.0245	No
114	Chrm2	Chrm2	16554	-0.201	-0.0246	No
115	F2rl1	F2rl1	16638	-0.204	-0.0255	No
116	F2rl3	F2rl3	17056	-0.224	-0.0404	No
117	Tbxa2r	Tbxa2r	17122	-0.227	-0.0402	No
118	S1pr2	S1pr2	17518	-0.246	-0.0538	No
119	Gprc5a	Gprc5a	17711	-0.256	-0.0587	No
120	Tshr	Tshr	17846	-0.262	-0.0610	No
121	Adgre5	Adgre5	17905	-0.265	-0.0600	No
122	Ednrb	Ednrb	18205	-0.280	-0.0691	No
123	Vipr1	Vipr1	18256	-0.282	-0.0676	No
124	P2ry13	P2ry13	18478	-0.293	-0.0732	No
125	Ltb4r1	Ltb4r1	18552	-0.297	-0.0725	No
126	Cx3cr1	Cx3cr1	18561	-0.298	-0.0689	No
127	Lpar2	Lpar2	18677	-0.303	-0.0699	No
128	Hcrtr1	Hcrtr1	18980	-0.320	-0.0786	No
129	Adgre4	Adgre4	18985	-0.321	-0.0746	No
130	Gpr65	Gpr65	19241	-0.336	-0.0811	No
131	Ccr2	Ccr2	19387	-0.347	-0.0828	No
132	Kiss1r	Kiss1r	19657	-0.366	-0.0895	No
133	S1pr4	S1pr4	19939	-0.387	-0.0965	No
134	Npy4r	Npy4r	20055	-0.397	-0.0962	No
135	Ffar4	Ffar4	20098	-0.400	-0.0928	No
136	Cxcr2	Cxcr2	20485	-0.438	-0.1036	No
137	Grm7	Grm7	20733	-0.464	-0.1081	No
138	Gpr17	Gpr17	20921	-0.485	-0.1097	No
139	Crhr2	Crhr2	21066	-0.501	-0.1094	No
140	Sucnr1	Sucnr1	21172	-0.514	-0.1072	No
141	Adrb3	Adrb3	21404	-0.548	-0.1099	No
142	Ptgir	Ptgir	21447	-0.555	-0.1045	No
143	Fpr1	Fpr1	21969	-0.647	-0.1183	No
144	Adcyap1r1	Adcyap1r1	22064	-0.669	-0.1137	No
145	Ptger2	Ptger2	22087	-0.676	-0.1058	No
146	Cxcr6	Cxcr6	22297	-0.730	-0.1053	No
147	Ptgfr	Ptgfr	22541	-0.806	-0.1052	No
148	Htr2b	Htr2b	22700	-0.871	-0.1006	No
149	Ptger4	Ptger4	22843	-0.942	-0.0945	No
150	Celsr3	Celsr3	23100	-1.116	-0.0909	No
151	Gpr68	Gpr68	23364	-1.420	-0.0837	No
152	Gipr	Gipr	23509	-1.839	-0.0660	No
153	Rxfp1	Rxfp1	23605	-2.649	-0.0358	No
154	Ntsr2	Ntsr2	23619	-2.901	0.0013	No

Fig 2: WP_GPCRS_NONODORANT   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_GPCRS_NONODORANT: Random ES distribution   
Gene set null distribution of ES for WP_GPCRS_NONODORANT