Details for gene set WP_LEPTININSULIN_SIGNALING_OVERLAP[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	WP_LEPTININSULIN_SIGNALING_OVERLAP
Enrichment Score (ES)	0.5157302
Normalized Enrichment Score (NES)	1.3329092
Nominal p-value	0.122
FDR q-value	0.38935888
FWER p-Value	0.904

Fig 1: Enrichment plot: WP_LEPTININSULIN_SIGNALING_OVERLAP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Irs1	Irs1	1207	0.829	0.1540	Yes
2	Akt1	Akt1	1613	0.701	0.3103	Yes
3	Insr	Insr	3900	0.367	0.3043	Yes
4	Lepr	Lepr	4013	0.357	0.3880	Yes
5	Dgkz	Dgkz	4272	0.336	0.4604	Yes
6	Stat3	Stat3	6366	0.204	0.4223	Yes
7	Pdpk1	Pdpk1	6478	0.199	0.4668	Yes
8	Socs3	Socs3	6484	0.198	0.5157	Yes
9	Irs3	Irs3	9129	0.084	0.4246	No
10	Irs2	Irs2	9891	0.053	0.4055	No
11	Socs1	Socs1	11022	0.013	0.3609	No
12	Pik3cg	Pik3cg	14778	-0.126	0.2333	No
13	Pik3r3	Pik3r3	15027	-0.136	0.2565	No
14	Jak2	Jak2	15840	-0.168	0.2638	No
15	Socs2	Socs2	17989	-0.269	0.2395	No

Fig 2: WP_LEPTININSULIN_SIGNALING_OVERLAP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_LEPTININSULIN_SIGNALING_OVERLAP: Random ES distribution   
Gene set null distribution of ES for WP_LEPTININSULIN_SIGNALING_OVERLAP