Details for gene set WP_P53

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	KO
GeneSet	WP_P53_SIGNALING
Enrichment Score (ES)	-0.5033915
Normalized Enrichment Score (NES)	-1.5664593
Nominal p-value	0.0
FDR q-value	0.36148992
FWER p-Value	0.573

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Gadd45a	Gadd45a	914	0.971	-0.0028	No
2	Sesn3	Sesn3	1240	0.811	0.0134	No
3	Steap3	Steap3	1536	0.720	0.0276	No
4	Ccnb3	Ccnb3	2615	0.505	0.0005	No
5	Cdk2	Cdk2	4769	0.298	-0.0797	No
6	Ccng1	Ccng1	5101	0.276	-0.0836	No
7	Fas	Fas	5290	0.262	-0.0818	No
8	Sesn2	Sesn2	6122	0.216	-0.1091	No
9	Casp3	Casp3	6368	0.204	-0.1119	No
10	Mdm4	Mdm4	6503	0.197	-0.1103	No
11	Ccng2	Ccng2	6895	0.179	-0.1203	No
12	Casp9	Casp9	7581	0.148	-0.1439	No
13	Tsc2	Tsc2	8338	0.113	-0.1717	No
14	Mdm2	Mdm2	8497	0.107	-0.1745	No
15	Ppm1d	Ppm1d	9609	0.064	-0.2192	No
16	Cycs	Cycs	10003	0.049	-0.2340	No
17	Cyct	Cyct	10767	0.022	-0.2656	No
18	Siah1b	Siah1b	11284	0.004	-0.2873	No
19	Cdk6	Cdk6	11294	0.004	-0.2875	No
20	Chek2	Chek2	12207	-0.028	-0.3252	No
21	Shisa5	Shisa5	12245	-0.029	-0.3257	No
22	Siah1a	Siah1a	12263	-0.030	-0.3253	No
23	Pten	Pten	12340	-0.032	-0.3273	No
24	Rrm2b	Rrm2b	12397	-0.034	-0.3284	No
25	Ddb2	Ddb2	12475	-0.037	-0.3303	No
26	Cop1	Cop1	13098	-0.060	-0.3545	No
27	Cd82	Cd82	14271	-0.105	-0.4003	No
28	Ei24	Ei24	14610	-0.118	-0.4102	No
29	Cdkn2a	Cdkn2a	14811	-0.128	-0.4140	No
30	Ccne2	Ccne2	15008	-0.135	-0.4173	No
31	Ccnb2	Ccnb2	15026	-0.136	-0.4130	No
32	Atr	Atr	15767	-0.165	-0.4382	No
33	Pidd1	Pidd1	15809	-0.167	-0.4338	No
34	Atm	Atm	16155	-0.182	-0.4417	No
35	Rchy1	Rchy1	16705	-0.207	-0.4573	No
36	Pmaip1	Pmaip1	17509	-0.246	-0.4823	No
37	Ccnb1-ps	Ccnb1-ps	17578	-0.249	-0.4759	No
38	Sfn	Sfn	17762	-0.259	-0.4741	No
39	Zmat3	Zmat3	17769	-0.259	-0.4648	No
40	Serpinb5	Serpinb5	18680	-0.303	-0.4922	Yes
41	Apaf1	Apaf1	18877	-0.314	-0.4889	Yes
42	Trp53	Trp53	18947	-0.319	-0.4800	Yes
43	Casp8	Casp8	18989	-0.321	-0.4699	Yes
44	Cdk1	Cdk1	19126	-0.330	-0.4634	Yes
45	Ccnb1	Ccnb1	19364	-0.345	-0.4607	Yes
46	Ccnd1	Ccnd1	19677	-0.368	-0.4604	Yes
47	Bax	Bax	20028	-0.394	-0.4606	Yes
48	Cdkn1a	Cdkn1a	20276	-0.417	-0.4557	Yes
49	Ccnd3	Ccnd3	20721	-0.463	-0.4574	Yes
50	Gadd45b	Gadd45b	20775	-0.468	-0.4423	Yes
51	Bbc3	Bbc3	20894	-0.482	-0.4295	Yes
52	Gtse1	Gtse1	21297	-0.532	-0.4269	Yes
53	Igfbp3	Igfbp3	21605	-0.577	-0.4185	Yes
54	Gadd45g	Gadd45g	21642	-0.584	-0.3984	Yes
55	Sesn1	Sesn1	22111	-0.681	-0.3931	Yes
56	Ccnd2	Ccnd2	22162	-0.693	-0.3696	Yes
57	Rrm2	Rrm2	22329	-0.737	-0.3493	Yes
58	Chek1	Chek1	22334	-0.739	-0.3222	Yes
59	Bid	Bid	22447	-0.771	-0.2984	Yes
60	Thbs1	Thbs1	22839	-0.941	-0.2802	Yes
61	Igf1	Igf1	22893	-0.967	-0.2467	Yes
62	Ccne1	Ccne1	23202	-1.192	-0.2156	Yes
63	Perp	Perp	23358	-1.410	-0.1700	Yes
64	Serpine1	Serpine1	23512	-1.845	-0.1083	Yes
65	Rprm	Rprm	23627	-3.083	0.0009	Yes