DatasetKO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
PhenotypeKO_vs_WTandHET.cls#WT_versus_KO
Upregulated in classWT
GeneSetWP_TCA_CYCLE
Enrichment Score (ES)0.46135488
Normalized Enrichment Score (NES)1.5118574
Nominal p-value0.05078125
FDR q-value0.43219277
FWER p-Value0.684
Table: GSEA Results Summary



Fig 1: Enrichment plot: WP_TCA_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1Sucla2Sucla213780.7680.0075Yes
2Idh3aIdh3a14260.7510.0698Yes
3Pdha1Pdha115720.7110.1246Yes
4Pdk4Pdk416690.6860.1794Yes
5Mdh2Mdh222990.5620.2009Yes
6Suclg1Suclg125510.5160.2345Yes
7Idh3gIdh3g27130.4890.2696Yes
8CsCs28770.4660.3027Yes
9Pdk1Pdk133610.4160.3179Yes
10SdhcSdhc37080.3830.3361Yes
11DldDld38220.3730.3633Yes
12SdhaSdha38600.3710.3935Yes
13Pdp2Pdp242270.3390.4071Yes
14PdhxPdhx42920.3350.4331Yes
15Pdk2Pdk243010.3340.4614Yes
16OgdhOgdh50360.2800.4542No
17DlatDlat63540.2040.4160No
18Idh3bIdh3b77340.1400.3696No
19Mdh1Mdh180900.1240.3652No
20SdhdSdhd87600.0970.3452No
21Idh2Idh288790.0930.3481No
22DlstDlst96260.0630.3219No
23Suclg2Suclg2103880.0350.2928No
24PdhbPdhb13976-0.0940.1489No
25Fh1Fh115707-0.1630.0897No
26Aco2Aco215908-0.1710.0959No
27SdhbSdhb16414-0.1930.0910No
28PcxPcx18818-0.3110.0159No
29Pdp1Pdp122100-0.679-0.0648No
30Pdk3Pdk323408-1.5200.0102No
Table: GSEA details [plain text format]



Fig 2: WP_TCA_CYCLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: WP_TCA_CYCLE: Random ES distribution   
Gene set null distribution of ES for WP_TCA_CYCLE