Details for gene set AMUNDSON_RESPONSE_TO

Table: GSEA Results Summary

Dataset	data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos
Phenotype	class.cls#24hr_versus_0hr_repos
Upregulated in class	24hr
GeneSet	AMUNDSON_RESPONSE_TO_ARSENITE
Enrichment Score (ES)	0.44239908
Normalized Enrichment Score (NES)	1.7747608
Nominal p-value	0.0
FDR q-value	0.54110265
FWER p-Value	0.599

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAFG	MAFG Entrez, Source	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	14	4.691	0.0140	Yes
2	AP4B1	AP4B1 Entrez, Source	adaptor-related protein complex 4, beta 1 subunit	15	4.674	0.0290	Yes
3	AHSA1	AHSA1 Entrez, Source	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	34	4.514	0.0422	Yes
4	MLLT11	MLLT11 Entrez, Source	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	37	4.508	0.0565	Yes
5	PRNP	PRNP Entrez, Source	prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)	46	4.474	0.0703	Yes
6	SOD1	SOD1 Entrez, Source	superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	69	4.376	0.0827	Yes
7	PRKCA	PRKCA Entrez, Source	protein kinase C, alpha	159	4.114	0.0894	Yes
8	RIT1	RIT1 Entrez, Source	Ras-like without CAAX 1	189	4.047	0.1003	Yes
9	E2F6	E2F6 Entrez, Source	E2F transcription factor 6	212	4.012	0.1115	Yes
10	TFE3	TFE3 Entrez, Source	transcription factor binding to IGHM enhancer 3	222	3.999	0.1237	Yes
11	STK17A	STK17A Entrez, Source	serine/threonine kinase 17a (apoptosis-inducing)	235	3.975	0.1356	Yes
12	ATP2C1	ATP2C1 Entrez, Source	ATPase, Ca++ transporting, type 2C, member 1	356	3.791	0.1390	Yes
13	CTH	CTH Entrez, Source	cystathionase (cystathionine gamma-lyase)	373	3.761	0.1499	Yes
14	IL10RA	IL10RA Entrez, Source	interleukin 10 receptor, alpha	424	3.690	0.1581	Yes
15	GLA	GLA Entrez, Source	galactosidase, alpha	492	3.618	0.1648	Yes
16	MAFF	MAFF Entrez, Source	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	495	3.617	0.1762	Yes
17	RPS6KC1	RPS6KC1 Entrez, Source	ribosomal protein S6 kinase, 52kDa, polypeptide 1	519	3.584	0.1861	Yes
18	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	531	3.574	0.1967	Yes
19	UBE2H	UBE2H Entrez, Source	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	575	3.508	0.2048	Yes
20	ME1	ME1 Entrez, Source	malic enzyme 1, NADP(+)-dependent, cytosolic	620	3.474	0.2128	Yes
21	CDC42EP3	CDC42EP3 Entrez, Source	CDC42 effector protein (Rho GTPase binding) 3	629	3.467	0.2233	Yes
22	HSPA1L	HSPA1L Entrez, Source	heat shock 70kDa protein 1-like	631	3.465	0.2343	Yes
23	TNFRSF10B	TNFRSF10B Entrez, Source	tumor necrosis factor receptor superfamily, member 10b	701	3.400	0.2402	Yes
24	BAG2	BAG2 Entrez, Source	BCL2-associated athanogene 2	787	3.317	0.2447	Yes
25	HSPA4	HSPA4 Entrez, Source	heat shock 70kDa protein 4	804	3.290	0.2541	Yes
26	PLOD1	PLOD1 Entrez, Source	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	839	3.255	0.2620	Yes
27	HSPA4L	HSPA4L Entrez, Source	heat shock 70kDa protein 4-like	854	3.232	0.2714	Yes
28	CPEB4	CPEB4 Entrez, Source	cytoplasmic polyadenylation element binding protein 4	865	3.224	0.2810	Yes
29	ADAM17	ADAM17 Entrez, Source	ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)	911	3.176	0.2879	Yes
30	DNAJA1	DNAJA1 Entrez, Source	DnaJ (Hsp40) homolog, subfamily A, member 1	971	3.102	0.2935	Yes
31	FHL2	FHL2 Entrez, Source	four and a half LIM domains 2	1099	2.975	0.2938	Yes
32	FXR1	FXR1 Entrez, Source	fragile X mental retardation, autosomal homolog 1	1128	2.947	0.3012	Yes
33	ETS2	ETS2 Entrez, Source	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	1162	2.921	0.3082	Yes
34	GTF3C3	GTF3C3 Entrez, Source	general transcription factor IIIC, polypeptide 3, 102kDa	1261	2.841	0.3101	Yes
35	HSPE1	HSPE1 Entrez, Source	heat shock 10kDa protein 1 (chaperonin 10)	1396	2.726	0.3091	Yes
36	EIF2S2	EIF2S2 Entrez, Source	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	1397	2.726	0.3179	Yes
37	ZNF187	ZNF187 Entrez, Source	zinc finger protein 187	1418	2.714	0.3251	Yes
38	DNAJB6	DNAJB6 Entrez, Source	DnaJ (Hsp40) homolog, subfamily B, member 6	1451	2.683	0.3314	Yes
39	CDC42EP1	CDC42EP1 Entrez, Source	CDC42 effector protein (Rho GTPase binding) 1	1487	2.644	0.3373	Yes
40	TMF1	TMF1 Entrez, Source	TATA element modulatory factor 1	1513	2.620	0.3439	Yes
41	MAN1A2	MAN1A2 Entrez, Source	mannosidase, alpha, class 1A, member 2	1588	2.564	0.3467	Yes
42	NFE2L2	NFE2L2 Entrez, Source	nuclear factor (erythroid-derived 2)-like 2	1606	2.550	0.3537	Yes
43	TIMM17A	TIMM17A Entrez, Source	translocase of inner mitochondrial membrane 17 homolog A (yeast)	1614	2.545	0.3613	Yes
44	MAPK7	MAPK7 Entrez, Source	mitogen-activated protein kinase 7	1620	2.541	0.3691	Yes
45	SERPINH1	SERPINH1 Entrez, Source	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	1672	2.493	0.3734	Yes
46	ATF3	ATF3 Entrez, Source	activating transcription factor 3	1699	2.474	0.3794	Yes
47	ST13	ST13 Entrez, Source	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	1713	2.467	0.3864	Yes
48	SLC1A4	SLC1A4 Entrez, Source	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	1745	2.444	0.3920	Yes
49	HIBCH	HIBCH Entrez, Source	3-hydroxyisobutyryl-Coenzyme A hydrolase	1815	2.393	0.3946	Yes
50	IL6ST	IL6ST Entrez, Source	interleukin 6 signal transducer (gp130, oncostatin M receptor)	1868	2.355	0.3984	Yes
51	DDIT3	DDIT3 Entrez, Source	DNA-damage-inducible transcript 3	1970	2.287	0.3983	Yes
52	PLTP	PLTP Entrez, Source	phospholipid transfer protein	1992	2.273	0.4041	Yes
53	TNKS	TNKS Entrez, Source	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	2045	2.227	0.4074	Yes
54	IGF2R	IGF2R Entrez, Source	insulin-like growth factor 2 receptor	2051	2.223	0.4142	Yes
55	WARS	WARS Entrez, Source	tryptophanyl-tRNA synthetase	2088	2.197	0.4186	Yes
56	NFE2L1	NFE2L1 Entrez, Source	nuclear factor (erythroid-derived 2)-like 1	2123	2.171	0.4231	Yes
57	BMP2K	BMP2K Entrez, Source	BMP2 inducible kinase	2177	2.129	0.4261	Yes
58	RELB	RELB Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)	2237	2.086	0.4285	Yes
59	CEBPB	CEBPB Entrez, Source	CCAAT/enhancer binding protein (C/EBP), beta	2273	2.056	0.4325	Yes
60	IARS	IARS Entrez, Source	isoleucine-tRNA synthetase	2385	1.988	0.4308	Yes
61	ATP6V0A1	ATP6V0A1 Entrez, Source	ATPase, H+ transporting, lysosomal V0 subunit a1	2388	1.987	0.4370	Yes
62	CCT8	CCT8 Entrez, Source	chaperonin containing TCP1, subunit 8 (theta)	2402	1.975	0.4424	Yes
63	GOLGB1	GOLGB1 Entrez, Source	golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1	2567	1.865	0.4364	No
64	ZNF24	ZNF24 Entrez, Source	zinc finger protein 24	2639	1.825	0.4371	No
65	ITGAX	ITGAX Entrez, Source	integrin, alpha X (complement component 3 receptor 4 subunit)	2698	1.789	0.4386	No
66	KIFC3	KIFC3 Entrez, Source	kinesin family member C3	2778	1.748	0.4385	No
67	MMD	MMD Entrez, Source	monocyte to macrophage differentiation-associated	2910	1.669	0.4343	No
68	GARS	GARS Entrez, Source	glycyl-tRNA synthetase	2915	1.666	0.4393	No
69	CCPG1	CCPG1 Entrez, Source	cell cycle progression 1	3020	1.610	0.4369	No
70	DNAJB4	DNAJB4 Entrez, Source	DnaJ (Hsp40) homolog, subfamily B, member 4	3150	1.536	0.4324	No
71	ARIH1	ARIH1 Entrez, Source	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	3327	1.435	0.4242	No
72	ATP6V1C1	ATP6V1C1 Entrez, Source	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	3362	1.419	0.4262	No
73	UBE2B	UBE2B Entrez, Source	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	3521	1.357	0.4191	No
74	ZFX	ZFX Entrez, Source	zinc finger protein, X-linked	3532	1.352	0.4227	No
75	CEBPG	CEBPG Entrez, Source	CCAAT/enhancer binding protein (C/EBP), gamma	3588	1.323	0.4229	No
76	BCAS2	BCAS2 Entrez, Source	breast carcinoma amplified sequence 2	3715	1.264	0.4178	No
77	ARNTL	ARNTL Entrez, Source	aryl hydrocarbon receptor nuclear translocator-like	3802	1.228	0.4154	No
78	IGFBP6	IGFBP6 Entrez, Source	insulin-like growth factor binding protein 6	3826	1.221	0.4177	No
79	STK10	STK10 Entrez, Source	serine/threonine kinase 10	3899	1.183	0.4162	No
80	ASNS	ASNS Entrez, Source	asparagine synthetase	3967	1.156	0.4151	No
81	SLC7A5	SLC7A5 Entrez, Source	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	4136	1.084	0.4063	No
82	TANK	TANK Entrez, Source	TRAF family member-associated NFKB activator	4208	1.062	0.4045	No
83	ATP6V0D1	ATP6V0D1 Entrez, Source	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	4253	1.052	0.4047	No
84	NEU1	NEU1 Entrez, Source	sialidase 1 (lysosomal sialidase)	4303	1.033	0.4044	No
85	MARS	MARS Entrez, Source	methionine-tRNA synthetase	4351	1.016	0.4042	No
86	HEXA	HEXA Entrez, Source	hexosaminidase A (alpha polypeptide)	4402	0.994	0.4038	No
87	SIAH2	SIAH2 Entrez, Source	seven in absentia homolog 2 (Drosophila)	4423	0.987	0.4055	No
88	CHERP	CHERP Entrez, Source	calcium homeostasis endoplasmic reticulum protein	4429	0.984	0.4083	No
89	RPL27	RPL27 Entrez, Source	ribosomal protein L27	4464	0.973	0.4089	No
90	CARS	CARS Entrez, Source	cysteinyl-tRNA synthetase	4608	0.916	0.4014	No
91	CLK1	CLK1 Entrez, Source	CDC-like kinase 1	4611	0.915	0.4042	No
92	TPP1	TPP1 Entrez, Source	tripeptidyl peptidase I	4762	0.861	0.3961	No
93	SPRR3	SPRR3 Entrez, Source	small proline-rich protein 3	4861	0.829	0.3916	No
94	GTF2H1	GTF2H1 Entrez, Source	general transcription factor IIH, polypeptide 1, 62kDa	4863	0.828	0.3941	No
95	RALGDS	RALGDS Entrez, Source	ral guanine nucleotide dissociation stimulator	5245	0.703	0.3686	No
96	BCAT1	BCAT1 Entrez, Source	branched chain aminotransferase 1, cytosolic	5475	0.632	0.3539	No
97	MT3	MT3 Entrez, Source	metallothionein 3 (growth inhibitory factor (neurotrophic))	5746	0.553	0.3360	No
98	SH2D3C	SH2D3C Entrez, Source	SH2 domain containing 3C	5872	0.516	0.3286	No
99	OGT	OGT Entrez, Source	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	5982	0.489	0.3222	No
100	DYRK1A	DYRK1A Entrez, Source	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	6066	0.466	0.3176	No
101	POLR1C	POLR1C Entrez, Source	polymerase (RNA) I polypeptide C, 30kDa	6204	0.430	0.3090	No
102	CLK2	CLK2 Entrez, Source	CDC-like kinase 2	6327	0.397	0.3014	No
103	APBA2	APBA2 Entrez, Source	amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)	6484	0.360	0.2912	No
104	HMBS	HMBS Entrez, Source	hydroxymethylbilane synthase	6654	0.318	0.2799	No
105	FUT4	FUT4 Entrez, Source	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	7040	0.215	0.2525	No
106	SLC22A1	SLC22A1 Entrez, Source	solute carrier family 22 (organic cation transporter), member 1	7204	0.173	0.2412	No
107	ZNF43	ZNF43 Entrez, Source	zinc finger protein 43	7246	0.162	0.2387	No
108	PFDN5	PFDN5 Entrez, Source	prefoldin subunit 5	7318	0.142	0.2340	No
109	EIF4EBP1	EIF4EBP1 Entrez, Source	eukaryotic translation initiation factor 4E binding protein 1	7548	0.085	0.2176	No
110	DNAJB5	DNAJB5 Entrez, Source	DnaJ (Hsp40) homolog, subfamily B, member 5	7589	0.073	0.2149	No
111	BCL2L2	BCL2L2 Entrez, Source	BCL2-like 2	7754	0.025	0.2030	No
112	TLE4	TLE4 Entrez, Source	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	7770	0.022	0.2020	No
113	ASB3	ASB3 Entrez, Source	ankyrin repeat and SOCS box-containing 3	7984	-0.036	0.1866	No
114	STC2	STC2 Entrez, Source	stanniocalcin 2	8194	-0.095	0.1716	No
115	TSC1	TSC1 Entrez, Source	tuberous sclerosis 1	8199	-0.097	0.1716	No
116	SCRN3	SCRN3 Entrez, Source	secernin 3	8392	-0.151	0.1581	No
117	FJX1	FJX1 Entrez, Source	four jointed box 1 (Drosophila)	8572	-0.205	0.1457	No
118	TAP1	TAP1 Entrez, Source	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	8782	-0.273	0.1314	No
119	RBM5	RBM5 Entrez, Source	RNA binding motif protein 5	8925	-0.322	0.1220	No
120	PEX11B	PEX11B Entrez, Source	peroxisomal biogenesis factor 11B	8950	-0.332	0.1214	No
121	GUCY1A3	GUCY1A3 Entrez, Source	guanylate cyclase 1, soluble, alpha 3	9066	-0.371	0.1142	No
122	NPM1	NPM1 Entrez, Source	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	9295	-0.441	0.0990	No
123	TBL1X	TBL1X Entrez, Source	transducin (beta)-like 1X-linked	9306	-0.448	0.0997	No
124	KCNF1	KCNF1 Entrez, Source	potassium voltage-gated channel, subfamily F, member 1	9377	-0.478	0.0961	No
125	STAT6	STAT6 Entrez, Source	signal transducer and activator of transcription 6, interleukin-4 induced	9466	-0.509	0.0913	No
126	SLC43A1	SLC43A1 Entrez, Source	solute carrier family 43, member 1	9594	-0.551	0.0838	No
127	ZNF85	ZNF85 Entrez, Source	zinc finger protein 85	9653	-0.575	0.0814	No
128	TUBGCP3	TUBGCP3 Entrez, Source	tubulin, gamma complex associated protein 3	9676	-0.584	0.0817	No
129	ID3	ID3 Entrez, Source	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	9773	-0.632	0.0767	No
130	CHD2	CHD2 Entrez, Source	chromodomain helicase DNA binding protein 2	9783	-0.636	0.0781	No
131	ST3GAL5	ST3GAL5 Entrez, Source	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	9931	-0.691	0.0696	No
132	RRAGA	RRAGA Entrez, Source	Ras-related GTP binding A	10031	-0.744	0.0648	No
133	MT1X	MT1X Entrez, Source	metallothionein 1X	10035	-0.745	0.0669	No
134	SPARCL1	SPARCL1 Entrez, Source	SPARC-like 1 (mast9, hevin)	10075	-0.765	0.0665	No
135	ESRRA	ESRRA Entrez, Source	estrogen-related receptor alpha	10104	-0.779	0.0670	No
136	MT1E	MT1E Entrez, Source	metallothionein 1E (functional)	10167	-0.810	0.0651	No
137	JUNB	JUNB Entrez, Source	jun B proto-oncogene	10192	-0.822	0.0660	No
138	TULP4	TULP4 Entrez, Source	tubby like protein 4	10273	-0.861	0.0629	No
139	REV3L	REV3L Entrez, Source	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	10333	-0.888	0.0614	No
140	LEPR	LEPR Entrez, Source	leptin receptor	10342	-0.895	0.0637	No
141	LYN	LYN Entrez, Source	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	10487	-0.962	0.0563	No
142	ANLN	ANLN Entrez, Source	anillin, actin binding protein	10497	-0.967	0.0588	No
143	DAZAP2	DAZAP2 Entrez, Source	DAZ associated protein 2	10548	-0.990	0.0583	No
144	MT1G	MT1G Entrez, Source	metallothionein 1G	10690	-1.062	0.0514	No
145	MT1B	MT1B Entrez, Source	metallothionein 1B (functional)	10738	-1.090	0.0515	No
146	BCL3	BCL3 Entrez, Source	B-cell CLL/lymphoma 3	10749	-1.097	0.0543	No
147	AKAP1	AKAP1 Entrez, Source	A kinase (PRKA) anchor protein 1	10771	-1.107	0.0563	No
148	RPUSD2	RPUSD2 Entrez, Source	RNA pseudouridylate synthase domain containing 2	10888	-1.168	0.0516	No
149	KLF12	KLF12 Entrez, Source	Kruppel-like factor 12	10962	-1.203	0.0501	No
150	TRIP13	TRIP13 Entrez, Source	thyroid hormone receptor interactor 13	11142	-1.294	0.0412	No
151	MT1L	MT1L Entrez, Source	metallothionein 1L (pseudogene)	11169	-1.310	0.0435	No
152	HIST1H2BD	HIST1H2BD Entrez, Source	histone cluster 1, H2bd	11355	-1.409	0.0346	No
153	RAD51AP1	RAD51AP1 Entrez, Source	RAD51 associated protein 1	11564	-1.549	0.0244	No
154	HPS5	HPS5 Entrez, Source	Hermansky-Pudlak syndrome 5	11821	-1.713	0.0112	No
155	EXT1	EXT1 Entrez, Source	exostoses (multiple) 1	11856	-1.744	0.0143	No
156	HYAL2	HYAL2 Entrez, Source	hyaluronoglucosaminidase 2	11942	-1.798	0.0139	No
157	ADNP	ADNP Entrez, Source	activity-dependent neuroprotector	11975	-1.822	0.0174	No
158	PIK3R4	PIK3R4 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 4, p150	12105	-1.921	0.0141	No
159	CIT	CIT Entrez, Source	citron (rho-interacting, serine/threonine kinase 21)	12143	-1.949	0.0177	No
160	GRN	GRN Entrez, Source	granulin	12406	-2.178	0.0056	No
161	ZNF184	ZNF184 Entrez, Source	zinc finger protein 184	12641	-2.398	-0.0038	No
162	DAG1	DAG1 Entrez, Source	dystroglycan 1 (dystrophin-associated glycoprotein 1)	12693	-2.459	0.0004	No
163	CTDSP1	CTDSP1 Entrez, Source	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	12818	-2.594	-0.0004	No
164	B3GNT6	B3GNT6 Entrez, Source	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)	12828	-2.608	0.0074	No
165	MT1F	MT1F Entrez, Source	metallothionein 1F (functional)	12932	-2.719	0.0086	No
166	ISYNA1	ISYNA1 Entrez, Source	-	13395	-3.305	-0.0145	No
167	DLC1	DLC1 Entrez, Source	deleted in liver cancer 1	13576	-3.610	-0.0161	No
168	NKTR	NKTR Entrez, Source	natural killer-tumor recognition sequence	13642	-3.753	-0.0088	No
169	PAXIP1	PAXIP1 Entrez, Source	PAX interacting (with transcription-activation domain) protein 1	13719	-3.956	-0.0016	No
170	CDK6	CDK6 Entrez, Source	cyclin-dependent kinase 6	13795	-4.214	0.0064	No