Datasetdata_collapsed_to_symbols.class.cls
#24hr_versus_0hr.class.cls
#24hr_versus_0hr_repos
Phenotypeclass.cls#24hr_versus_0hr_repos
Upregulated in class0hr
GeneSetKAMMINGA_SENESCENCE
Enrichment Score (ES)-0.48255455
Normalized Enrichment Score (NES)-1.5737627
Nominal p-value0.105788425
FDR q-value1.0
FWER p-Value0.941
Table: GSEA Results Summary



Fig 1: Enrichment plot: KAMMINGA_SENESCENCE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FHITFHIT
Entrez,  Source
fragile histidine triad gene32101.503-0.1906No
2NOL9NOL9
Entrez,  Source
nucleolar protein 933281.435-0.1599No
3GNAO1GNAO1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O42301.058-0.1960No
4CCAR1CCAR1
Entrez,  Source
cell division cycle and apoptosis regulator 147390.869-0.2089No
5CPN1CPN1
Entrez,  Source
carboxypeptidase N, polypeptide 1, 50kD48860.823-0.1970No
6KPNB1KPNB1
Entrez,  Source
karyopherin (importin) beta 149090.816-0.1763No
7QTRT1QTRT1
Entrez,  Source
queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase)52700.694-0.1833No
8MLLT6MLLT6
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 659570.494-0.2194No
9CLK2CLK2
Entrez,  Source
CDC-like kinase 263270.397-0.2352No
10ABHD8ABHD8
Entrez,  Source
abhydrolase domain containing 863530.391-0.2263No
11DDX54DDX54
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5464320.373-0.2217No
12WHSC2WHSC2
Entrez,  Source
Wolf-Hirschhorn syndrome candidate 264760.362-0.2149No
13DHRSXDHRSX
Entrez,  Source
dehydrogenase/reductase (SDR family) X-linked67310.301-0.2250No
14GRPGRP
Entrez,  Source
gastrin-releasing peptide71930.175-0.2535No
15RABAC1RABAC1
Entrez,  Source
Rab acceptor 1 (prenylated)76630.050-0.2860No
16ARID1AARID1A
Entrez,  Source
AT rich interactive domain 1A (SWI- like)8734-0.254-0.3563No
17ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein10109-0.782-0.4341No
18PLEKHA7PLEKHA7
Entrez,  Source
pleckstrin homology domain containing, family A member 710781-1.111-0.4522Yes
19GTF2E1GTF2E1
Entrez,  Source
general transcription factor IIE, polypeptide 1, alpha 56kDa11171-1.312-0.4444Yes
20KYNUKYNU
Entrez,  Source
kynureninase (L-kynurenine hydrolase)11183-1.317-0.4092Yes
21ELAVL1ELAVL1
Entrez,  Source
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)11511-1.510-0.3916Yes
22MKI67MKI67
Entrez,  Source
antigen identified by monoclonal antibody Ki-6711692-1.628-0.3601Yes
23ALG10ALG10
Entrez,  Source
asparagine-linked glycosylation 10 homolog (yeast, alpha-1,2-glucosyltransferase)11791-1.693-0.3209Yes
24TCEA3TCEA3
Entrez,  Source
transcription elongation factor A (SII), 312317-2.089-0.3017Yes
25SUOXSUOX
Entrez,  Source
sulfite oxidase12326-2.098-0.2450Yes
26THBS4THBS4
Entrez,  Source
thrombospondin 412464-2.230-0.1940Yes
27EZH2EZH2
Entrez,  Source
enhancer of zeste homolog 2 (Drosophila)12505-2.264-0.1350Yes
28ARHGEF10LARHGEF10L
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 10-like12672-2.439-0.0804Yes
29HMGN1HMGN1
Entrez,  Source
high-mobility group nucleosome binding domain 113221-3.067-0.0361Yes
30PLEKHG2PLEKHG2
Entrez,  Source
pleckstrin homology domain containing, family G (with RhoGef domain) member 213226-3.0690.0474Yes
Table: GSEA details [plain text format]



Fig 2: KAMMINGA_SENESCENCE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: KAMMINGA_SENESCENCE: Random ES distribution   
Gene set null distribution of ES for KAMMINGA_SENESCENCE