Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 24hr |
| GeneSet | KRIEG_HYPOXIA_VIA_KDM3A |
| Enrichment Score (ES) | 0.56814367 |
| Normalized Enrichment Score (NES) | 1.838329 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.55126 |
| FWER p-Value | 0.412 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 110 | 4.274 | 0.0464 | Yes |
| 2 | SERPINB8 | SERPINB8 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 305 | 3.878 | 0.0817 | Yes |
| 3 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 316 | 3.859 | 0.1300 | Yes |
| 4 | PHLDA2 | PHLDA2 Entrez, Source | pleckstrin homology-like domain, family A, member 2 | 447 | 3.660 | 0.1671 | Yes |
| 5 | SEC14L2 | SEC14L2 Entrez, Source | SEC14-like 2 (S. cerevisiae) | 505 | 3.602 | 0.2088 | Yes |
| 6 | PPP1R15A | PPP1R15A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 515 | 3.592 | 0.2538 | Yes |
| 7 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 606 | 3.483 | 0.2915 | Yes |
| 8 | ASPH | ASPH Entrez, Source | aspartate beta-hydroxylase | 778 | 3.329 | 0.3215 | Yes |
| 9 | CBR3 | CBR3 Entrez, Source | carbonyl reductase 3 | 814 | 3.282 | 0.3607 | Yes |
| 10 | NFKBIE | NFKBIE Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 864 | 3.224 | 0.3981 | Yes |
| 11 | MAP3K14 | MAP3K14 Entrez, Source | mitogen-activated protein kinase kinase kinase 14 | 1408 | 2.721 | 0.3935 | Yes |
| 12 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 1474 | 2.658 | 0.4225 | Yes |
| 13 | ADM | ADM Entrez, Source | adrenomedullin | 1506 | 2.625 | 0.4537 | Yes |
| 14 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 1808 | 2.397 | 0.4624 | Yes |
| 15 | MARCH3 | MARCH3 Entrez, Source | membrane-associated ring finger (C3HC4) 3 | 2368 | 2.000 | 0.4474 | Yes |
| 16 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 2430 | 1.961 | 0.4679 | Yes |
| 17 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 2476 | 1.924 | 0.4891 | Yes |
| 18 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 2678 | 1.799 | 0.4975 | Yes |
| 19 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 2711 | 1.782 | 0.5178 | Yes |
| 20 | NECAP2 | NECAP2 Entrez, Source | NECAP endocytosis associated 2 | 2802 | 1.733 | 0.5333 | Yes |
| 21 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 3223 | 1.499 | 0.5221 | Yes |
| 22 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 3364 | 1.418 | 0.5300 | Yes |
| 23 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 3373 | 1.416 | 0.5474 | Yes |
| 24 | TM4SF1 | TM4SF1 Entrez, Source | transmembrane 4 L six family member 1 | 3519 | 1.357 | 0.5541 | Yes |
| 25 | RRAGD | RRAGD Entrez, Source | Ras-related GTP binding D | 3561 | 1.334 | 0.5681 | Yes |
| 26 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 5512 | 0.620 | 0.4352 | No |
| 27 | STEAP3 | STEAP3 Entrez, Source | STEAP family member 3 | 8359 | -0.141 | 0.2314 | No |
| 28 | SYTL3 | SYTL3 Entrez, Source | synaptotagmin-like 3 | 8516 | -0.187 | 0.2225 | No |
| 29 | COL7A1 | COL7A1 Entrez, Source | collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) | 9237 | -0.424 | 0.1759 | No |
| 30 | FBXO32 | FBXO32 Entrez, Source | F-box protein 32 | 9516 | -0.526 | 0.1625 | No |
| 31 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 10002 | -0.729 | 0.1367 | No |
| 32 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 10192 | -0.822 | 0.1335 | No |
| 33 | EBP | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 10323 | -0.884 | 0.1353 | No |
| 34 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 10378 | -0.915 | 0.1431 | No |
| 35 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 10807 | -1.128 | 0.1265 | No |
| 36 | FAM64A | FAM64A Entrez, Source | family with sequence similarity 64, member A | 10909 | -1.178 | 0.1342 | No |
| 37 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 10930 | -1.188 | 0.1478 | No |
| 38 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 11376 | -1.423 | 0.1338 | No |
| 39 | TM4SF19 | TM4SF19 Entrez, Source | transmembrane 4 L six family member 19 | 11767 | -1.676 | 0.1269 | No |
| 40 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12248 | -2.036 | 0.1181 | No |
