Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | RIZ_ERYTHROID_DIFFERENTIATION_HBZ |
| Enrichment Score (ES) | -0.62094593 |
| Normalized Enrichment Score (NES) | -1.5808393 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.941 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ZNF436 | ZNF436 Entrez, Source | zinc finger protein 436 | 2280 | 2.049 | -0.1221 | No |
| 2 | PAPOLA | PAPOLA Entrez, Source | poly(A) polymerase alpha | 2447 | 1.950 | -0.0937 | No |
| 3 | FOSB | FOSB Entrez, Source | FBJ murine osteosarcoma viral oncogene homolog B | 5230 | 0.707 | -0.2799 | No |
| 4 | TAL2 | TAL2 Entrez, Source | T-cell acute lymphocytic leukemia 2 | 5239 | 0.705 | -0.2658 | No |
| 5 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 5853 | 0.522 | -0.2993 | No |
| 6 | SOX18 | SOX18 Entrez, Source | SRY (sex determining region Y)-box 18 | 6701 | 0.308 | -0.3540 | No |
| 7 | MPL | MPL Entrez, Source | myeloproliferative leukemia virus oncogene | 7390 | 0.122 | -0.4012 | No |
| 8 | NR5A1 | NR5A1 Entrez, Source | nuclear receptor subfamily 5, group A, member 1 | 7411 | 0.118 | -0.4002 | No |
| 9 | NKX2-5 | NKX2-5 Entrez, Source | NK2 transcription factor related, locus 5 (Drosophila) | 7474 | 0.103 | -0.4025 | No |
| 10 | POU3F3 | POU3F3 Entrez, Source | POU domain, class 3, transcription factor 3 | 8795 | -0.276 | -0.4920 | No |
| 11 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 9706 | -0.600 | -0.5453 | No |
| 12 | SIX2 | SIX2 Entrez, Source | sine oculis homeobox homolog 2 (Drosophila) | 9951 | -0.700 | -0.5484 | No |
| 13 | SOX4 | SOX4 Entrez, Source | SRY (sex determining region Y)-box 4 | 10005 | -0.731 | -0.5371 | No |
| 14 | HOXB13 | HOXB13 Entrez, Source | homeobox B13 | 11168 | -1.309 | -0.5938 | Yes |
| 15 | TFAP2C | TFAP2C Entrez, Source | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 11280 | -1.371 | -0.5734 | Yes |
| 16 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 11298 | -1.382 | -0.5460 | Yes |
| 17 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 11490 | -1.500 | -0.5287 | Yes |
| 18 | TBX2 | TBX2 Entrez, Source | T-box 2 | 11540 | -1.532 | -0.5005 | Yes |
| 19 | EYA2 | EYA2 Entrez, Source | eyes absent homolog 2 (Drosophila) | 11545 | -1.535 | -0.4690 | Yes |
| 20 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 12048 | -1.873 | -0.4664 | Yes |
| 21 | TMPO | TMPO Entrez, Source | thymopoietin | 12113 | -1.931 | -0.4310 | Yes |
| 22 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 12275 | -2.058 | -0.4000 | Yes |
| 23 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 12567 | -2.329 | -0.3727 | Yes |
| 24 | POU3F2 | POU3F2 Entrez, Source | POU domain, class 3, transcription factor 2 | 12584 | -2.345 | -0.3253 | Yes |
| 25 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12673 | -2.441 | -0.2810 | Yes |
| 26 | E2F8 | E2F8 Entrez, Source | E2F transcription factor 8 | 12684 | -2.447 | -0.2311 | Yes |
| 27 | POU2F3 | POU2F3 Entrez, Source | POU domain, class 2, transcription factor 3 | 12790 | -2.553 | -0.1857 | Yes |
| 28 | SMARCD2 | SMARCD2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 12960 | -2.753 | -0.1409 | Yes |
| 29 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 13161 | -3.015 | -0.0928 | Yes |
| 30 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 13250 | -3.102 | -0.0349 | Yes |
| 31 | CBX7 | CBX7 Entrez, Source | chromobox homolog 7 | 13690 | -3.886 | 0.0139 | Yes |
