Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 24hr |
| GeneSet | SAGIV_CD24_TARGETS_DN |
| Enrichment Score (ES) | 0.55780077 |
| Normalized Enrichment Score (NES) | 1.7548279 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.5325649 |
| FWER p-Value | 0.7 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPHK1 | SPHK1 Entrez, Source | sphingosine kinase 1 | 183 | 4.062 | 0.0505 | Yes |
| 2 | RNF25 | RNF25 Entrez, Source | ring finger protein 25 | 433 | 3.683 | 0.0904 | Yes |
| 3 | PPP1R15A | PPP1R15A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 515 | 3.592 | 0.1409 | Yes |
| 4 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 540 | 3.562 | 0.1951 | Yes |
| 5 | EPHB6 | EPHB6 Entrez, Source | EPH receptor B6 | 645 | 3.451 | 0.2417 | Yes |
| 6 | ULBP2 | ULBP2 Entrez, Source | UL16 binding protein 2 | 684 | 3.415 | 0.2926 | Yes |
| 7 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 882 | 3.202 | 0.3286 | Yes |
| 8 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 1200 | 2.898 | 0.3512 | Yes |
| 9 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 1266 | 2.836 | 0.3910 | Yes |
| 10 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1699 | 2.474 | 0.3987 | Yes |
| 11 | CTTN | CTTN Entrez, Source | cortactin | 1807 | 2.397 | 0.4286 | Yes |
| 12 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 1835 | 2.377 | 0.4639 | Yes |
| 13 | GEM | GEM Entrez, Source | GTP binding protein overexpressed in skeletal muscle | 2155 | 2.141 | 0.4745 | Yes |
| 14 | ECM1 | ECM1 Entrez, Source | extracellular matrix protein 1 | 2183 | 2.125 | 0.5059 | Yes |
| 15 | RELB | RELB Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian) | 2237 | 2.086 | 0.5348 | Yes |
| 16 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 2430 | 1.961 | 0.5517 | Yes |
| 17 | FOXD1 | FOXD1 Entrez, Source | forkhead box D1 | 2983 | 1.631 | 0.5374 | Yes |
| 18 | LAT2 | LAT2 Entrez, Source | linker for activation of T cells family, member 2 | 3048 | 1.591 | 0.5578 | Yes |
| 19 | THBS1 | THBS1 Entrez, Source | thrombospondin 1 | 5373 | 0.665 | 0.4004 | No |
| 20 | UROD | UROD Entrez, Source | uroporphyrinogen decarboxylase | 5990 | 0.488 | 0.3636 | No |
| 21 | TUFT1 | TUFT1 Entrez, Source | tuftelin 1 | 6262 | 0.416 | 0.3505 | No |
| 22 | MCAM | MCAM Entrez, Source | melanoma cell adhesion molecule | 6912 | 0.252 | 0.3076 | No |
| 23 | LPPR2 | LPPR2 Entrez, Source | - | 7157 | 0.183 | 0.2928 | No |
| 24 | HOMER3 | HOMER3 Entrez, Source | homer homolog 3 (Drosophila) | 8335 | -0.133 | 0.2099 | No |
| 25 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 8502 | -0.183 | 0.2008 | No |
| 26 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 8603 | -0.213 | 0.1969 | No |
| 27 | BIK | BIK Entrez, Source | BCL2-interacting killer (apoptosis-inducing) | 8760 | -0.268 | 0.1899 | No |
| 28 | LDB1 | LDB1 Entrez, Source | LIM domain binding 1 | 9038 | -0.363 | 0.1756 | No |
| 29 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 9307 | -0.448 | 0.1633 | No |
| 30 | APOBEC3B | APOBEC3B Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 9537 | -0.530 | 0.1550 | No |
| 31 | CST6 | CST6 Entrez, Source | cystatin E/M | 9740 | -0.617 | 0.1501 | No |
| 32 | PDGFB | PDGFB Entrez, Source | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 10121 | -0.786 | 0.1350 | No |
| 33 | OGG1 | OGG1 Entrez, Source | 8-oxoguanine DNA glycosylase | 10345 | -0.896 | 0.1330 | No |
| 34 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 10359 | -0.904 | 0.1462 | No |
| 35 | KLHL22 | KLHL22 Entrez, Source | kelch-like 22 (Drosophila) | 10435 | -0.938 | 0.1555 | No |
| 36 | HSD17B6 | HSD17B6 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 6 | 11555 | -1.543 | 0.0989 | No |
| 37 | TRIM8 | TRIM8 Entrez, Source | tripartite motif-containing 8 | 11560 | -1.547 | 0.1229 | No |
| 38 | N4BP3 | N4BP3 Entrez, Source | - | 13043 | -2.852 | 0.0607 | No |
