Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | SHEPARD_BMYB_MORPHOLINO_DN |
| Enrichment Score (ES) | -0.3859432 |
| Normalized Enrichment Score (NES) | -1.5737659 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.941 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EPDR1 | EPDR1 Entrez, Source | ependymin related protein 1 (zebrafish) | 23 | 4.568 | 0.0197 | No |
| 2 | CIDEC | CIDEC Entrez, Source | cell death-inducing DFFA-like effector c | 82 | 4.345 | 0.0358 | No |
| 3 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 118 | 4.253 | 0.0531 | No |
| 4 | PFKFB4 | PFKFB4 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 161 | 4.102 | 0.0692 | No |
| 5 | BLVRB | BLVRB Entrez, Source | biliverdin reductase B (flavin reductase (NADPH)) | 350 | 3.797 | 0.0733 | No |
| 6 | PHF20L1 | PHF20L1 Entrez, Source | PHD finger protein 20-like 1 | 925 | 3.160 | 0.0463 | No |
| 7 | SEPT6 | SEPT6 Entrez, Source | septin 6 | 1607 | 2.549 | 0.0086 | No |
| 8 | FGFR4 | FGFR4 Entrez, Source | fibroblast growth factor receptor 4 | 1762 | 2.423 | 0.0088 | No |
| 9 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 1913 | 2.322 | 0.0087 | No |
| 10 | COTL1 | COTL1 Entrez, Source | coactosin-like 1 (Dictyostelium) | 1934 | 2.308 | 0.0180 | No |
| 11 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 1989 | 2.275 | 0.0247 | No |
| 12 | CLDN1 | CLDN1 Entrez, Source | claudin 1 | 2011 | 2.258 | 0.0338 | No |
| 13 | EOMES | EOMES Entrez, Source | eomesodermin homolog (Xenopus laevis) | 2218 | 2.100 | 0.0286 | No |
| 14 | GOLGB1 | GOLGB1 Entrez, Source | golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 | 2567 | 1.865 | 0.0120 | No |
| 15 | GPSM1 | GPSM1 Entrez, Source | G-protein signalling modulator 1 (AGS3-like, C. elegans) | 2672 | 1.803 | 0.0128 | No |
| 16 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 3021 | 1.610 | -0.0050 | No |
| 17 | DRAP1 | DRAP1 Entrez, Source | DR1-associated protein 1 (negative cofactor 2 alpha) | 3110 | 1.552 | -0.0041 | No |
| 18 | PTPRN | PTPRN Entrez, Source | protein tyrosine phosphatase, receptor type, N | 3161 | 1.529 | -0.0006 | No |
| 19 | C3 | C3 Entrez, Source | complement component 3 | 3371 | 1.416 | -0.0092 | No |
| 20 | SLC25A24 | SLC25A24 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 3469 | 1.375 | -0.0098 | No |
| 21 | MTHFD1L | MTHFD1L Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 3587 | 1.323 | -0.0121 | No |
| 22 | NOVA2 | NOVA2 Entrez, Source | neuro-oncological ventral antigen 2 | 3919 | 1.175 | -0.0307 | No |
| 23 | TNXB | TNXB Entrez, Source | tenascin XB | 4070 | 1.114 | -0.0364 | No |
| 24 | GRHPR | GRHPR Entrez, Source | glyoxylate reductase/hydroxypyruvate reductase | 4190 | 1.066 | -0.0401 | No |
| 25 | MDM4 | MDM4 Entrez, Source | Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) | 4259 | 1.050 | -0.0402 | No |
| 26 | KRT17 | KRT17 Entrez, Source | keratin 17 | 4348 | 1.017 | -0.0418 | No |
| 27 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 4408 | 0.992 | -0.0415 | No |
| 28 | CHERP | CHERP Entrez, Source | calcium homeostasis endoplasmic reticulum protein | 4429 | 0.984 | -0.0383 | No |
| 29 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 4469 | 0.972 | -0.0366 | No |
| 30 | PDCL | PDCL Entrez, Source | phosducin-like | 4514 | 0.955 | -0.0354 | No |
| 31 | SOX21 | SOX21 Entrez, Source | SRY (sex determining region Y)-box 21 | 4903 | 0.818 | -0.0598 | No |
| 32 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 4906 | 0.817 | -0.0561 | No |
| 33 | PSAT1 | PSAT1 Entrez, Source | phosphoserine aminotransferase 1 | 5154 | 0.737 | -0.0706 | No |
| 34 | RAX | RAX Entrez, Source | retina and anterior neural fold homeobox | 5233 | 0.706 | -0.0730 | No |
| 35 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 5341 | 0.676 | -0.0776 | No |
| 36 | INPP4A | INPP4A Entrez, Source | inositol polyphosphate-4-phosphatase, type I, 107kDa | 5407 | 0.656 | -0.0793 | No |
| 37 | SLC2A5 | SLC2A5 Entrez, Source | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 5569 | 0.605 | -0.0882 | No |
| 38 | DAP | DAP Entrez, Source | death-associated protein | 5639 | 0.588 | -0.0904 | No |
| 39 | DLX2 | DLX2 Entrez, Source | distal-less homeobox 2 | 5768 | 0.547 | -0.0972 | No |
| 40 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 5982 | 0.489 | -0.1104 | No |
| 41 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 6016 | 0.481 | -0.1105 | No |
| 42 | GPT2 | GPT2 Entrez, Source | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 6218 | 0.428 | -0.1232 | No |
| 43 | STRA6 | STRA6 Entrez, Source | stimulated by retinoic acid gene 6 homolog (mouse) | 6235 | 0.424 | -0.1224 | No |
| 44 | F7 | F7 Entrez, Source | coagulation factor VII (serum prothrombin conversion accelerator) | 6236 | 0.423 | -0.1204 | No |
| 45 | SFRP1 | SFRP1 Entrez, Source | secreted frizzled-related protein 1 | 6608 | 0.330 | -0.1458 | No |
| 46 | PVALB | PVALB Entrez, Source | parvalbumin | 6638 | 0.321 | -0.1464 | No |
| 47 | SLC6A13 | SLC6A13 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 6657 | 0.317 | -0.1463 | No |
| 48 | PYGL | PYGL Entrez, Source | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 6673 | 0.314 | -0.1459 | No |
| 49 | RTKN | RTKN Entrez, Source | rhotekin | 6843 | 0.271 | -0.1569 | No |
| 50 | RBP4 | RBP4 Entrez, Source | retinol binding protein 4, plasma | 6982 | 0.231 | -0.1659 | No |
| 51 | NSD1 | NSD1 Entrez, Source | nuclear receptor binding SET domain protein 1 | 7120 | 0.194 | -0.1749 | No |
| 52 | CA1 | CA1 Entrez, Source | carbonic anhydrase I | 7211 | 0.171 | -0.1807 | No |
| 53 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 7354 | 0.132 | -0.1904 | No |
| 54 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 7454 | 0.106 | -0.1971 | No |
| 55 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 7515 | 0.092 | -0.2010 | No |
| 56 | VTN | VTN Entrez, Source | vitronectin | 7560 | 0.082 | -0.2039 | No |
| 57 | APOE | APOE Entrez, Source | apolipoprotein E | 7583 | 0.075 | -0.2051 | No |
| 58 | POU3F1 | POU3F1 Entrez, Source | POU domain, class 3, transcription factor 1 | 7734 | 0.031 | -0.2159 | No |
| 59 | CDC14B | CDC14B Entrez, Source | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 7848 | 0.000 | -0.2241 | No |
| 60 | CDCA3 | CDCA3 Entrez, Source | cell division cycle associated 3 | 7978 | -0.034 | -0.2333 | No |
| 61 | DLX1 | DLX1 Entrez, Source | distal-less homeobox 1 | 7995 | -0.040 | -0.2343 | No |
| 62 | AEBP1 | AEBP1 Entrez, Source | AE binding protein 1 | 8018 | -0.046 | -0.2357 | No |
| 63 | LHX1 | LHX1 Entrez, Source | LIM homeobox 1 | 8300 | -0.122 | -0.2556 | No |
| 64 | SLC4A2 | SLC4A2 Entrez, Source | solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) | 8735 | -0.255 | -0.2859 | No |
| 65 | POU3F3 | POU3F3 Entrez, Source | POU domain, class 3, transcription factor 3 | 8795 | -0.276 | -0.2889 | No |
| 66 | HEY1 | HEY1 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 1 | 8819 | -0.286 | -0.2893 | No |
| 67 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 8922 | -0.322 | -0.2952 | No |
| 68 | IQGAP3 | IQGAP3 Entrez, Source | IQ motif containing GTPase activating protein 3 | 9095 | -0.379 | -0.3059 | No |
| 69 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 9185 | -0.407 | -0.3105 | No |
| 70 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 9871 | -0.668 | -0.3572 | No |
| 71 | KAL1 | KAL1 Entrez, Source | Kallmann syndrome 1 sequence | 9899 | -0.677 | -0.3560 | No |
| 72 | MGAT4B | MGAT4B Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 10202 | -0.828 | -0.3741 | No |
| 73 | TOP1MT | TOP1MT Entrez, Source | topoisomerase (DNA) I, mitochondrial | 10314 | -0.881 | -0.3781 | No |
| 74 | SOX11 | SOX11 Entrez, Source | SRY (sex determining region Y)-box 11 | 10423 | -0.933 | -0.3816 | Yes |
| 75 | AQP1 | AQP1 Entrez, Source | aquaporin 1 (Colton blood group) | 10448 | -0.946 | -0.3789 | Yes |
| 76 | TGM1 | TGM1 Entrez, Source | transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) | 10458 | -0.950 | -0.3751 | Yes |
| 77 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 10492 | -0.965 | -0.3730 | Yes |
| 78 | ANLN | ANLN Entrez, Source | anillin, actin binding protein | 10497 | -0.967 | -0.3688 | Yes |
| 79 | SLC29A2 | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 10573 | -1.007 | -0.3695 | Yes |
| 80 | COL4A5 | COL4A5 Entrez, Source | collagen, type IV, alpha 5 (Alport syndrome) | 10579 | -1.010 | -0.3652 | Yes |
| 81 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 10706 | -1.073 | -0.3693 | Yes |
| 82 | MELK | MELK Entrez, Source | maternal embryonic leucine zipper kinase | 10714 | -1.079 | -0.3648 | Yes |
| 83 | TTK | TTK Entrez, Source | TTK protein kinase | 10811 | -1.130 | -0.3665 | Yes |
| 84 | MAB21L2 | MAB21L2 Entrez, Source | mab-21-like 2 (C. elegans) | 10947 | -1.196 | -0.3707 | Yes |
| 85 | KIF23 | KIF23 Entrez, Source | kinesin family member 23 | 10948 | -1.196 | -0.3652 | Yes |
| 86 | MASTL | MASTL Entrez, Source | microtubule associated serine/threonine kinase-like | 10975 | -1.208 | -0.3614 | Yes |
| 87 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 11087 | -1.267 | -0.3636 | Yes |
| 88 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11213 | -1.334 | -0.3664 | Yes |
| 89 | GTSE1 | GTSE1 Entrez, Source | G-2 and S-phase expressed 1 | 11216 | -1.335 | -0.3603 | Yes |
| 90 | AURKB | AURKB Entrez, Source | aurora kinase B | 11304 | -1.385 | -0.3602 | Yes |
| 91 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11310 | -1.387 | -0.3541 | Yes |
| 92 | KIF11 | KIF11 Entrez, Source | kinesin family member 11 | 11382 | -1.427 | -0.3526 | Yes |
| 93 | MT2A | MT2A Entrez, Source | metallothionein 2A | 11386 | -1.430 | -0.3461 | Yes |
| 94 | C8G | C8G Entrez, Source | complement component 8, gamma polypeptide | 11467 | -1.488 | -0.3450 | Yes |
| 95 | TACC3 | TACC3 Entrez, Source | transforming, acidic coiled-coil containing protein 3 | 11507 | -1.507 | -0.3408 | Yes |
| 96 | CDC6 | CDC6 Entrez, Source | CDC6 cell division cycle 6 homolog (S. cerevisiae) | 11557 | -1.545 | -0.3371 | Yes |
| 97 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 11565 | -1.550 | -0.3304 | Yes |
| 98 | FBXO5 | FBXO5 Entrez, Source | F-box protein 5 | 11624 | -1.586 | -0.3272 | Yes |
| 99 | ASPM | ASPM Entrez, Source | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 11642 | -1.599 | -0.3209 | Yes |
| 100 | MKI67 | MKI67 Entrez, Source | antigen identified by monoclonal antibody Ki-67 | 11692 | -1.628 | -0.3169 | Yes |
| 101 | CDCA2 | CDCA2 Entrez, Source | cell division cycle associated 2 | 11713 | -1.639 | -0.3107 | Yes |
| 102 | PRC1 | PRC1 Entrez, Source | protein regulator of cytokinesis 1 | 11716 | -1.641 | -0.3032 | Yes |
| 103 | CKAP2 | CKAP2 Entrez, Source | cytoskeleton associated protein 2 | 11802 | -1.696 | -0.3014 | Yes |
| 104 | FAHD2A | FAHD2A Entrez, Source | fumarylacetoacetate hydrolase domain containing 2A | 11839 | -1.727 | -0.2960 | Yes |
| 105 | GALC | GALC Entrez, Source | galactosylceramidase | 11912 | -1.782 | -0.2929 | Yes |
| 106 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 12013 | -1.847 | -0.2915 | Yes |
| 107 | DCK | DCK Entrez, Source | deoxycytidine kinase | 12043 | -1.872 | -0.2849 | Yes |
| 108 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 12048 | -1.873 | -0.2764 | Yes |
| 109 | GMNN | GMNN Entrez, Source | geminin, DNA replication inhibitor | 12238 | -2.026 | -0.2807 | Yes |
| 110 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 12275 | -2.058 | -0.2737 | Yes |
| 111 | TK1 | TK1 Entrez, Source | thymidine kinase 1, soluble | 12422 | -2.191 | -0.2741 | Yes |
| 112 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12432 | -2.197 | -0.2645 | Yes |
| 113 | UHRF1 | UHRF1 Entrez, Source | ubiquitin-like, containing PHD and RING finger domains, 1 | 12560 | -2.322 | -0.2629 | Yes |
| 114 | POU3F2 | POU3F2 Entrez, Source | POU domain, class 3, transcription factor 2 | 12584 | -2.345 | -0.2536 | Yes |
| 115 | TPX2 | TPX2 Entrez, Source | TPX2, microtubule-associated, homolog (Xenopus laevis) | 12594 | -2.350 | -0.2433 | Yes |
| 116 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 12669 | -2.437 | -0.2373 | Yes |
| 117 | WDR76 | WDR76 Entrez, Source | WD repeat domain 76 | 12707 | -2.479 | -0.2284 | Yes |
| 118 | ARHGEF10 | ARHGEF10 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 10 | 12745 | -2.522 | -0.2193 | Yes |
| 119 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 12815 | -2.590 | -0.2122 | Yes |
| 120 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 12846 | -2.625 | -0.2021 | Yes |
| 121 | HELLS | HELLS Entrez, Source | helicase, lymphoid-specific | 12850 | -2.627 | -0.1900 | Yes |
| 122 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 13014 | -2.804 | -0.1888 | Yes |
| 123 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 13041 | -2.851 | -0.1774 | Yes |
| 124 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 13051 | -2.863 | -0.1646 | Yes |
| 125 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 13099 | -2.929 | -0.1544 | Yes |
| 126 | MCM2 | MCM2 Entrez, Source | MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) | 13166 | -3.018 | -0.1451 | Yes |
| 127 | TM7SF2 | TM7SF2 Entrez, Source | transmembrane 7 superfamily member 2 | 13207 | -3.053 | -0.1337 | Yes |
| 128 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 13239 | -3.089 | -0.1215 | Yes |
| 129 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 13257 | -3.117 | -0.1082 | Yes |
| 130 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 13321 | -3.220 | -0.0978 | Yes |
| 131 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 13354 | -3.254 | -0.0849 | Yes |
| 132 | CCNG2 | CCNG2 Entrez, Source | cyclin G2 | 13358 | -3.262 | -0.0699 | Yes |
| 133 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 13512 | -3.496 | -0.0646 | Yes |
| 134 | SFXN2 | SFXN2 Entrez, Source | sideroflexin 2 | 13628 | -3.721 | -0.0556 | Yes |
| 135 | MCM3 | MCM3 Entrez, Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 13643 | -3.758 | -0.0391 | Yes |
| 136 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 13647 | -3.767 | -0.0217 | Yes |
| 137 | PAXIP1 | PAXIP1 Entrez, Source | PAX interacting (with transcription-activation domain) protein 1 | 13719 | -3.956 | -0.0084 | Yes |
| 138 | SYNGR1 | SYNGR1 Entrez, Source | synaptogyrin 1 | 13815 | -4.331 | 0.0049 | Yes |
