Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | BIOCARTA_PTEN_PATHWAY |
| Enrichment Score (ES) | -0.41729715 |
| Normalized Enrichment Score (NES) | -1.412471 |
| Nominal p-value | 0.109561756 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 976 | 3.099 | 0.0278 | No |
| 2 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 1294 | 2.815 | 0.0942 | No |
| 3 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 1887 | 2.339 | 0.1256 | No |
| 4 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 3186 | 1.519 | 0.0802 | No |
| 5 | SOS1 | SOS1 Entrez, Source | son of sevenless homolog 1 (Drosophila) | 3376 | 1.415 | 0.1114 | No |
| 6 | PDPK1 | PDPK1 Entrez, Source | 3-phosphoinositide dependent protein kinase-1 | 3387 | 1.409 | 0.1553 | No |
| 7 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 4096 | 1.102 | 0.1392 | No |
| 8 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 5783 | 0.544 | 0.0349 | No |
| 9 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 7054 | 0.211 | -0.0500 | No |
| 10 | ILK | ILK Entrez, Source | integrin-linked kinase | 9380 | -0.479 | -0.2025 | No |
| 11 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12360 | -2.133 | -0.3497 | Yes |
| 12 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12479 | -2.240 | -0.2872 | Yes |
| 13 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 12603 | -2.354 | -0.2215 | Yes |
| 14 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 13275 | -3.148 | -0.1701 | Yes |
| 15 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 13437 | -3.371 | -0.0749 | Yes |
| 16 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 13443 | -3.374 | 0.0317 | Yes |
