Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | KEGG_BASE_EXCISION_REPAIR |
| Enrichment Score (ES) | -0.42520514 |
| Normalized Enrichment Score (NES) | -1.3868905 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NEIL2 | NEIL2 Entrez, Source | nei like 2 (E. coli) | 673 | 3.429 | 0.0107 | No |
| 2 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 1281 | 2.825 | 0.0157 | No |
| 3 | MBD4 | MBD4 Entrez, Source | methyl-CpG binding domain protein 4 | 2031 | 2.239 | 0.0004 | No |
| 4 | POLL | POLL Entrez, Source | polymerase (DNA directed), lambda | 2227 | 2.094 | 0.0225 | No |
| 5 | TDG | TDG Entrez, Source | thymine-DNA glycosylase | 2254 | 2.073 | 0.0565 | No |
| 6 | MUTYH | MUTYH Entrez, Source | mutY homolog (E. coli) | 3719 | 1.264 | -0.0274 | No |
| 7 | LIG3 | LIG3 Entrez, Source | ligase III, DNA, ATP-dependent | 3738 | 1.257 | -0.0070 | No |
| 8 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 5011 | 0.781 | -0.0853 | No |
| 9 | PARP3 | PARP3 Entrez, Source | poly (ADP-ribose) polymerase family, member 3 | 5097 | 0.755 | -0.0783 | No |
| 10 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 6242 | 0.422 | -0.1536 | No |
| 11 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 6797 | 0.286 | -0.1887 | No |
| 12 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 9200 | -0.410 | -0.3550 | No |
| 13 | POLE | POLE Entrez, Source | polymerase (DNA directed), epsilon | 9437 | -0.498 | -0.3634 | No |
| 14 | POLE4 | POLE4 Entrez, Source | polymerase (DNA-directed), epsilon 4 (p12 subunit) | 10059 | -0.760 | -0.3951 | No |
| 15 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10277 | -0.863 | -0.3958 | No |
| 16 | OGG1 | OGG1 Entrez, Source | 8-oxoguanine DNA glycosylase | 10345 | -0.896 | -0.3852 | No |
| 17 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 10606 | -1.021 | -0.3863 | No |
| 18 | SMUG1 | SMUG1 Entrez, Source | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 10681 | -1.057 | -0.3734 | No |
| 19 | PARP2 | PARP2 Entrez, Source | poly (ADP-ribose) polymerase family, member 2 | 10704 | -1.072 | -0.3564 | No |
| 20 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 11658 | -1.610 | -0.3974 | Yes |
| 21 | NEIL1 | NEIL1 Entrez, Source | nei endonuclease VIII-like 1 (E. coli) | 11882 | -1.764 | -0.3830 | Yes |
| 22 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12296 | -2.073 | -0.3770 | Yes |
| 23 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 12539 | -2.300 | -0.3547 | Yes |
| 24 | POLE2 | POLE2 Entrez, Source | polymerase (DNA directed), epsilon 2 (p59 subunit) | 12776 | -2.544 | -0.3277 | Yes |
| 25 | APEX2 | APEX2 Entrez, Source | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | 12804 | -2.576 | -0.2851 | Yes |
| 26 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 13041 | -2.851 | -0.2529 | Yes |
| 27 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 13250 | -3.102 | -0.2143 | Yes |
| 28 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 13326 | -3.223 | -0.1640 | Yes |
| 29 | XRCC1 | XRCC1 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 1 | 13591 | -3.644 | -0.1200 | Yes |
| 30 | NTHL1 | NTHL1 Entrez, Source | nth endonuclease III-like 1 (E. coli) | 13740 | -4.005 | -0.0615 | Yes |
| 31 | MPG | MPG Entrez, Source | N-methylpurine-DNA glycosylase | 13777 | -4.149 | 0.0077 | Yes |
