Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | KEGG_DNA_REPLICATION |
| Enrichment Score (ES) | -0.66894585 |
| Normalized Enrichment Score (NES) | -1.4187014 |
| Nominal p-value | 0.08113591 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 4268 | 1.047 | -0.2880 | No |
| 2 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 6242 | 0.422 | -0.4223 | No |
| 3 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 6797 | 0.286 | -0.4568 | No |
| 4 | RNASEH1 | RNASEH1 Entrez, Source | ribonuclease H1 | 6869 | 0.264 | -0.4568 | No |
| 5 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 7170 | 0.179 | -0.4751 | No |
| 6 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9404 | -0.489 | -0.6269 | No |
| 7 | POLE | POLE Entrez, Source | polymerase (DNA directed), epsilon | 9437 | -0.498 | -0.6196 | No |
| 8 | POLE4 | POLE4 Entrez, Source | polymerase (DNA-directed), epsilon 4 (p12 subunit) | 10059 | -0.760 | -0.6498 | Yes |
| 9 | RPA4 | RPA4 Entrez, Source | replication protein A4, 34kDa | 10180 | -0.816 | -0.6428 | Yes |
| 10 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 10238 | -0.846 | -0.6306 | Yes |
| 11 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 10606 | -1.021 | -0.6375 | Yes |
| 12 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10667 | -1.050 | -0.6217 | Yes |
| 13 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 11062 | -1.254 | -0.6260 | Yes |
| 14 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 11658 | -1.610 | -0.6380 | Yes |
| 15 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11774 | -1.680 | -0.6140 | Yes |
| 16 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 12048 | -1.873 | -0.5977 | Yes |
| 17 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 12081 | -1.900 | -0.5635 | Yes |
| 18 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 12275 | -2.058 | -0.5379 | Yes |
| 19 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12296 | -2.073 | -0.4995 | Yes |
| 20 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 12362 | -2.134 | -0.4632 | Yes |
| 21 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12432 | -2.197 | -0.4259 | Yes |
| 22 | RFC5 | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 12486 | -2.247 | -0.3866 | Yes |
| 23 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 12539 | -2.300 | -0.3461 | Yes |
| 24 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 12609 | -2.360 | -0.3058 | Yes |
| 25 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12673 | -2.441 | -0.2634 | Yes |
| 26 | POLE2 | POLE2 Entrez, Source | polymerase (DNA directed), epsilon 2 (p59 subunit) | 12776 | -2.544 | -0.2219 | Yes |
| 27 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 13033 | -2.836 | -0.1859 | Yes |
| 28 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 13041 | -2.851 | -0.1316 | Yes |
| 29 | MCM2 | MCM2 Entrez, Source | MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) | 13166 | -3.018 | -0.0825 | Yes |
| 30 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 13326 | -3.223 | -0.0321 | Yes |
| 31 | MCM3 | MCM3 Entrez, Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 13643 | -3.758 | 0.0173 | Yes |
