Details for gene set KEGG_ENDOCYTOSIS[GSEA]

Table: GSEA Results Summary

Dataset	data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos
Phenotype	class.cls#24hr_versus_0hr_repos
Upregulated in class	24hr
GeneSet	KEGG_ENDOCYTOSIS
Enrichment Score (ES)	0.4083311
Normalized Enrichment Score (NES)	1.7203771
Nominal p-value	0.0
FDR q-value	0.959073
FWER p-Value	0.634

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HSPA1A	HSPA1A Entrez, Source	heat shock 70kDa protein 1A	101	4.293	0.0101	Yes
2	CLTB	CLTB Entrez, Source	clathrin, light chain (Lcb)	164	4.096	0.0223	Yes
3	VPS37A	VPS37A Entrez, Source	vacuolar protein sorting 37 homolog A (S. cerevisiae)	194	4.044	0.0366	Yes
4	HGS	HGS Entrez, Source	hepatocyte growth factor-regulated tyrosine kinase substrate	229	3.991	0.0504	Yes
5	EHD4	EHD4 Entrez, Source	EH-domain containing 4	275	3.930	0.0631	Yes
6	AP2B1	AP2B1 Entrez, Source	adaptor-related protein complex 2, beta 1 subunit	340	3.811	0.0740	Yes
7	HLA-E	HLA-E Entrez, Source	major histocompatibility complex, class I, E	371	3.766	0.0871	Yes
8	RABEP1	RABEP1 Entrez, Source	rabaptin, RAB GTPase binding effector protein 1	382	3.749	0.1017	Yes
9	HLA-F	HLA-F Entrez, Source	major histocompatibility complex, class I, F	393	3.740	0.1162	Yes
10	HSPA8	HSPA8 Entrez, Source	heat shock 70kDa protein 8	413	3.704	0.1299	Yes
11	ZFYVE20	ZFYVE20 Entrez, Source	zinc finger, FYVE domain containing 20	442	3.664	0.1428	Yes
12	STAM	STAM Entrez, Source	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	487	3.625	0.1543	Yes
13	HLA-B	HLA-B Entrez, Source	major histocompatibility complex, class I, B	530	3.575	0.1658	Yes
14	ARFGAP1	ARFGAP1 Entrez, Source	ADP-ribosylation factor GTPase activating protein 1	570	3.520	0.1773	Yes
15	HSPA6	HSPA6 Entrez, Source	heat shock 70kDa protein 6 (HSP70B')	583	3.500	0.1907	Yes
16	HSPA1L	HSPA1L Entrez, Source	heat shock 70kDa protein 1-like	631	3.465	0.2014	Yes
17	DNM1L	DNM1L Entrez, Source	dynamin 1-like	650	3.445	0.2141	Yes
18	SMURF1	SMURF1 Entrez, Source	SMAD specific E3 ubiquitin protein ligase 1	727	3.381	0.2223	Yes
19	DNM1	DNM1 Entrez, Source	dynamin 1	760	3.344	0.2336	Yes
20	HLA-C	HLA-C Entrez, Source	major histocompatibility complex, class I, C	783	3.325	0.2455	Yes
21	HLA-A	HLA-A Entrez, Source	major histocompatibility complex, class I, A	862	3.227	0.2530	Yes
22	RAB11FIP5	RAB11FIP5 Entrez, Source	RAB11 family interacting protein 5 (class I)	941	3.138	0.2601	Yes
23	RAB22A	RAB22A Entrez, Source	RAB22A, member RAS oncogene family	946	3.137	0.2726	Yes
24	MDM2	MDM2 Entrez, Source	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)	1046	3.022	0.2777	Yes
25	SH3KBP1	SH3KBP1 Entrez, Source	SH3-domain kinase binding protein 1	1110	2.964	0.2851	Yes
26	TRAF6	TRAF6 Entrez, Source	TNF receptor-associated factor 6	1338	2.771	0.2799	Yes
27	CHMP2B	CHMP2B Entrez, Source	chromatin modifying protein 2B	1360	2.758	0.2896	Yes
28	RAB5A	RAB5A Entrez, Source	RAB5A, member RAS oncogene family	1432	2.705	0.2955	Yes
29	VPS4A	VPS4A Entrez, Source	vacuolar protein sorting 4 homolog A (S. cerevisiae)	1546	2.593	0.2978	Yes
30	VPS37B	VPS37B Entrez, Source	vacuolar protein sorting 37 homolog B (S. cerevisiae)	1612	2.547	0.3034	Yes
31	FLT1	FLT1 Entrez, Source	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	1639	2.524	0.3118	Yes
32	CHMP5	CHMP5 Entrez, Source	chromatin modifying protein 5	1707	2.469	0.3170	Yes
33	FGFR4	FGFR4 Entrez, Source	fibroblast growth factor receptor 4	1762	2.423	0.3229	Yes
34	RAB5C	RAB5C Entrez, Source	RAB5C, member RAS oncogene family	1797	2.403	0.3302	Yes
35	SMAP1	SMAP1 Entrez, Source	stromal membrane-associated protein 1	1828	2.384	0.3378	Yes
36	EGFR	EGFR Entrez, Source	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	1847	2.367	0.3461	Yes
37	PLD1	PLD1 Entrez, Source	phospholipase D1, phosphatidylcholine-specific	1876	2.345	0.3536	Yes
38	HLA-G	HLA-G Entrez, Source	HLA-G histocompatibility antigen, class I, G	1909	2.323	0.3607	Yes
39	ITCH	ITCH Entrez, Source	itchy homolog E3 ubiquitin protein ligase (mouse)	1991	2.274	0.3641	Yes
40	CHMP6	CHMP6 Entrez, Source	chromatin modifying protein 6	2158	2.140	0.3607	Yes
41	CLTC	CLTC Entrez, Source	clathrin, heavy chain (Hc)	2202	2.108	0.3662	Yes
42	PIP5K1A	PIP5K1A Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	2236	2.087	0.3723	Yes
43	EHD2	EHD2 Entrez, Source	EH-domain containing 2	2365	2.003	0.3711	Yes
44	RAB11FIP1	RAB11FIP1 Entrez, Source	RAB11 family interacting protein 1 (class I)	2401	1.977	0.3766	Yes
45	CHMP4B	CHMP4B Entrez, Source	chromatin modifying protein 4B	2507	1.908	0.3767	Yes
46	SMURF2	SMURF2 Entrez, Source	SMAD specific E3 ubiquitin protein ligase 2	2538	1.880	0.3822	Yes
47	CBL	CBL Entrez, Source	Cas-Br-M (murine) ecotropic retroviral transforming sequence	2701	1.785	0.3777	Yes
48	ADRBK2	ADRBK2 Entrez, Source	adrenergic, beta, receptor kinase 2	2731	1.771	0.3828	Yes
49	MET	MET Entrez, Source	met proto-oncogene (hepatocyte growth factor receptor)	2823	1.720	0.3831	Yes
50	STAM2	STAM2 Entrez, Source	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	2911	1.669	0.3836	Yes
51	EEA1	EEA1 Entrez, Source	early endosome antigen 1, 162kD	2918	1.664	0.3899	Yes
52	USP8	USP8 Entrez, Source	ubiquitin specific peptidase 8	2955	1.644	0.3940	Yes
53	CSF1R	CSF1R Entrez, Source	colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog	2994	1.624	0.3979	Yes
54	IGF1R	IGF1R Entrez, Source	insulin-like growth factor 1 receptor	3113	1.551	0.3956	Yes
55	LDLR	LDLR Entrez, Source	low density lipoprotein receptor (familial hypercholesterolemia)	3176	1.525	0.3973	Yes
56	PDCD6IP	PDCD6IP Entrez, Source	programmed cell death 6 interacting protein	3249	1.484	0.3981	Yes
57	CDC42	CDC42 Entrez, Source	cell division cycle 42 (GTP binding protein, 25kDa)	3290	1.458	0.4011	Yes
58	IQSEC3	IQSEC3 Entrez, Source	IQ motif and Sec7 domain 3	3300	1.455	0.4064	Yes
59	SH3GLB1	SH3GLB1 Entrez, Source	SH3-domain GRB2-like endophilin B1	3425	1.392	0.4030	Yes
60	GIT2	GIT2 Entrez, Source	G protein-coupled receptor kinase interactor 2	3431	1.391	0.4083	Yes
61	CHMP4C	CHMP4C Entrez, Source	chromatin modifying protein 4C	3639	1.301	0.3986	No
62	SH3GL1	SH3GL1 Entrez, Source	SH3-domain GRB2-like 1	3885	1.189	0.3856	No
63	VPS4B	VPS4B Entrez, Source	vacuolar protein sorting 4 homolog B (S. cerevisiae)	3996	1.141	0.3822	No
64	RAB11FIP2	RAB11FIP2 Entrez, Source	RAB11 family interacting protein 2 (class I)	4012	1.135	0.3857	No
65	VPS25	VPS25 Entrez, Source	vacuolar protein sorting 25 homolog (S. cerevisiae)	4099	1.101	0.3840	No
66	ARFGAP3	ARFGAP3 Entrez, Source	ADP-ribosylation factor GTPase activating protein 3	4714	0.880	0.3429	No
67	CLTA	CLTA Entrez, Source	clathrin, light chain (Lca)	4972	0.796	0.3274	No
68	EHD1	EHD1 Entrez, Source	EH-domain containing 1	4984	0.793	0.3298	No
69	GIT1	GIT1 Entrez, Source	G protein-coupled receptor kinase interactor 1	5040	0.775	0.3290	No
70	RNF41	RNF41 Entrez, Source	ring finger protein 41	5100	0.754	0.3278	No
71	ADRB3	ADRB3 Entrez, Source	adrenergic, beta-3-, receptor	5408	0.655	0.3081	No
72	EPN1	EPN1 Entrez, Source	epsin 1	5766	0.548	0.2843	No
73	F2R	F2R Entrez, Source	coagulation factor II (thrombin) receptor	6011	0.482	0.2685	No
74	CBLB	CBLB Entrez, Source	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	6093	0.460	0.2645	No
75	PRKCI	PRKCI Entrez, Source	protein kinase C, iota	6096	0.458	0.2662	No
76	CHMP1B	CHMP1B Entrez, Source	chromatin modifying protein 1B	6115	0.454	0.2668	No
77	ADRBK1	ADRBK1 Entrez, Source	adrenergic, beta, receptor kinase 1	6297	0.405	0.2553	No
78	CXCR4	CXCR4 Entrez, Source	chemokine (C-X-C motif) receptor 4	6329	0.396	0.2546	No
79	AP2A2	AP2A2 Entrez, Source	adaptor-related protein complex 2, alpha 2 subunit	6340	0.395	0.2555	No
80	STAMBP	STAMBP Entrez, Source	STAM binding protein	6841	0.272	0.2202	No
81	IL2RG	IL2RG Entrez, Source	interleukin 2 receptor, gamma (severe combined immunodeficiency)	6873	0.261	0.2190	No
82	PIP5K1C	PIP5K1C Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	6902	0.254	0.2180	No
83	PARD3	PARD3 Entrez, Source	par-3 partitioning defective 3 homolog (C. elegans)	6929	0.245	0.2171	No
84	LDLRAP1	LDLRAP1 Entrez, Source	low density lipoprotein receptor adaptor protein 1	7073	0.207	0.2076	No
85	DNM2	DNM2 Entrez, Source	dynamin 2	7444	0.109	0.1811	No
86	TFRC	TFRC Entrez, Source	transferrin receptor (p90, CD71)	7814	0.011	0.1543	No
87	GRK1	GRK1 Entrez, Source	G protein-coupled receptor kinase 1	7829	0.006	0.1533	No
88	EPS15	EPS15 Entrez, Source	epidermal growth factor receptor pathway substrate 15	8091	-0.069	0.1346	No
89	RAB5B	RAB5B Entrez, Source	RAB5B, member RAS oncogene family	8270	-0.116	0.1221	No
90	TSG101	TSG101 Entrez, Source	tumor susceptibility gene 101	8317	-0.126	0.1193	No
91	PARD6G	PARD6G Entrez, Source	par-6 partitioning defective 6 homolog gamma (C. elegans)	8383	-0.148	0.1151	No
92	SNF8	SNF8 Entrez, Source	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	8427	-0.160	0.1127	No
93	RAB31	RAB31 Entrez, Source	RAB31, member RAS oncogene family	8459	-0.172	0.1111	No
94	AP2M1	AP2M1 Entrez, Source	adaptor-related protein complex 2, mu 1 subunit	8718	-0.250	0.0933	No
95	RAB11FIP3	RAB11FIP3 Entrez, Source	RAB11 family interacting protein 3 (class II)	8739	-0.256	0.0929	No
96	RUFY1	RUFY1 Entrez, Source	RUN and FYVE domain containing 1	8844	-0.291	0.0865	No
97	GRK5	GRK5 Entrez, Source	G protein-coupled receptor kinase 5	8932	-0.325	0.0815	No
98	IQSEC1	IQSEC1 Entrez, Source	IQ motif and Sec7 domain 1	8934	-0.325	0.0828	No
99	GRK6	GRK6 Entrez, Source	G protein-coupled receptor kinase 6	8974	-0.340	0.0813	No
100	AP2A1	AP2A1 Entrez, Source	adaptor-related protein complex 2, alpha 1 subunit	8997	-0.348	0.0812	No
101	AP2S1	AP2S1 Entrez, Source	adaptor-related protein complex 2, sigma 1 subunit	9065	-0.371	0.0778	No
102	RAB11B	RAB11B Entrez, Source	RAB11B, member RAS oncogene family	9132	-0.392	0.0746	No
103	VPS37D	VPS37D Entrez, Source	vacuolar protein sorting 37 homolog D (S. cerevisiae)	9143	-0.396	0.0755	No
104	CHMP4A	CHMP4A Entrez, Source	chromatin modifying protein 4A	9245	-0.426	0.0698	No
105	WWP1	WWP1 Entrez, Source	WW domain containing E3 ubiquitin protein ligase 1	9265	-0.431	0.0702	No
106	SRC	SRC Entrez, Source	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	9276	-0.435	0.0713	No
107	CCR5	CCR5 Entrez, Source	chemokine (C-C motif) receptor 5	9439	-0.499	0.0615	No
108	HSPA2	HSPA2 Entrez, Source	heat shock 70kDa protein 2	9448	-0.501	0.0630	No
109	CLTCL1	CLTCL1 Entrez, Source	clathrin, heavy chain-like 1	9451	-0.502	0.0649	No
110	VPS37C	VPS37C Entrez, Source	vacuolar protein sorting 37 homolog C (S. cerevisiae)	9604	-0.553	0.0560	No
111	RAB11A	RAB11A Entrez, Source	RAB11A, member RAS oncogene family	9785	-0.637	0.0455	No
112	NEDD4L	NEDD4L Entrez, Source	neural precursor cell expressed, developmentally down-regulated 4-like	10025	-0.741	0.0312	No
113	IL2RB	IL2RB Entrez, Source	interleukin 2 receptor, beta	10132	-0.791	0.0267	No
114	EHD3	EHD3 Entrez, Source	EH-domain containing 3	10366	-0.908	0.0134	No
115	PLD2	PLD2 Entrez, Source	phospholipase D2	10402	-0.922	0.0146	No
116	ARRB1	ARRB1 Entrez, Source	arrestin, beta 1	10427	-0.935	0.0167	No
117	DAB2	DAB2 Entrez, Source	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	10564	-1.003	0.0109	No
118	NEDD4	NEDD4 Entrez, Source	neural precursor cell expressed, developmentally down-regulated 4	10785	-1.114	-0.0006	No
119	SH3GL3	SH3GL3 Entrez, Source	SH3-domain GRB2-like 3	10802	-1.126	0.0028	No
120	PRKCZ	PRKCZ Entrez, Source	protein kinase C, zeta	10911	-1.179	-0.0003	No
121	ERBB3	ERBB3 Entrez, Source	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	11287	-1.375	-0.0219	No
122	FGFR2	FGFR2 Entrez, Source	ffer syndrome, Jackson-Weiss syndrome)	11474	-1.492	-0.0294	No
123	VPS28	VPS28 Entrez, Source	vacuolar protein sorting 28 homolog (S. cerevisiae)	11496	-1.502	-0.0248	No
124	RAB11FIP4	RAB11FIP4 Entrez, Source	RAB11 family interacting protein 4 (class II)	11607	-1.577	-0.0264	No
125	ARF6	ARF6 Entrez, Source	ADP-ribosylation factor 6	11904	-1.777	-0.0407	No
126	EPN3	EPN3 Entrez, Source	epsin 3	12012	-1.847	-0.0410	No
127	CHMP2A	CHMP2A Entrez, Source	chromatin modifying protein 2A	12232	-2.024	-0.0487	No
128	HRAS	HRAS Entrez, Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	12302	-2.076	-0.0452	No
129	IQSEC2	IQSEC2 Entrez, Source	IQ motif and Sec7 domain 2	12308	-2.082	-0.0371	No
130	FGFR3	FGFR3 Entrez, Source	fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)	12454	-2.215	-0.0387	No
131	PSD3	PSD3 Entrez, Source	pleckstrin and Sec7 domain containing 3	12578	-2.336	-0.0381	No
132	ARRB2	ARRB2 Entrez, Source	arrestin, beta 2	12637	-2.393	-0.0326	No
133	PSD4	PSD4 Entrez, Source	pleckstrin and Sec7 domain containing 4	12800	-2.567	-0.0339	No
134	RAB4A	RAB4A Entrez, Source	RAB4A, member RAS oncogene family	12926	-2.715	-0.0320	No
135	RET	RET Entrez, Source	ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)	12935	-2.726	-0.0215	No
136	PARD6A	PARD6A Entrez, Source	par-6 partitioning defective 6 homolog alpha (C.elegans)	12978	-2.768	-0.0132	No
137	GRK4	GRK4 Entrez, Source	G protein-coupled receptor kinase 4	13116	-2.958	-0.0112	No
138	DNM3	DNM3 Entrez, Source	dynamin 3	13215	-3.058	-0.0058	No
139	EPN2	EPN2 Entrez, Source	epsin 2	13317	-3.211	-0.0001	No
140	SH3GLB2	SH3GLB2 Entrez, Source	SH3-domain GRB2-like endophilin B2	13391	-3.300	0.0080	No
141	PIP5K1B	PIP5K1B Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	13439	-3.371	0.0183	No
142	ERBB4	ERBB4 Entrez, Source	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	13474	-3.424	0.0298	No