Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | KEGG_MISMATCH_REPAIR |
| Enrichment Score (ES) | -0.60392255 |
| Normalized Enrichment Score (NES) | -1.3734666 |
| Nominal p-value | 0.07797271 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MLH1 | MLH1 Entrez, Source | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 3208 | 1.505 | -0.1912 | No |
| 2 | PMS2 | PMS2 Entrez, Source | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 4126 | 1.089 | -0.2282 | No |
| 3 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 4268 | 1.047 | -0.2104 | No |
| 4 | MLH3 | MLH3 Entrez, Source | mutL homolog 3 (E. coli) | 5954 | 0.495 | -0.3187 | No |
| 5 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 6242 | 0.422 | -0.3282 | No |
| 6 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 7170 | 0.179 | -0.3903 | No |
| 7 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 8318 | -0.126 | -0.4697 | No |
| 8 | RPA4 | RPA4 Entrez, Source | replication protein A4, 34kDa | 10180 | -0.816 | -0.5821 | Yes |
| 9 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 10238 | -0.846 | -0.5636 | Yes |
| 10 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 10606 | -1.021 | -0.5628 | Yes |
| 11 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10667 | -1.050 | -0.5390 | Yes |
| 12 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 11062 | -1.254 | -0.5339 | Yes |
| 13 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 11658 | -1.610 | -0.5338 | Yes |
| 14 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11774 | -1.680 | -0.4972 | Yes |
| 15 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 12081 | -1.900 | -0.4685 | Yes |
| 16 | EXO1 | EXO1 Entrez, Source | exonuclease 1 | 12092 | -1.908 | -0.4182 | Yes |
| 17 | RFC5 | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 12486 | -2.247 | -0.3865 | Yes |
| 18 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 12539 | -2.300 | -0.3287 | Yes |
| 19 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 13033 | -2.836 | -0.2885 | Yes |
| 20 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 13041 | -2.851 | -0.2128 | Yes |
| 21 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 13326 | -3.223 | -0.1471 | Yes |
| 22 | MSH6 | MSH6 Entrez, Source | mutS homolog 6 (E. coli) | 13340 | -3.233 | -0.0616 | Yes |
| 23 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 13647 | -3.767 | 0.0170 | Yes |
