Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | KEGG_TRYPTOPHAN_METABOLISM |
| Enrichment Score (ES) | -0.5177492 |
| Normalized Enrichment Score (NES) | -1.5287244 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.86 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 2088 | 2.197 | -0.1008 | No |
| 2 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 3610 | 1.312 | -0.1808 | No |
| 3 | WARS2 | WARS2 Entrez, Source | tryptophanyl tRNA synthetase 2 (mitochondrial) | 3818 | 1.222 | -0.1680 | No |
| 4 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 3832 | 1.217 | -0.1412 | No |
| 5 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 4091 | 1.103 | -0.1348 | No |
| 6 | AANAT | AANAT Entrez, Source | arylalkylamine N-acetyltransferase | 4512 | 0.956 | -0.1434 | No |
| 7 | OGDH | OGDH Entrez, Source | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 5012 | 0.781 | -0.1617 | No |
| 8 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 5077 | 0.762 | -0.1490 | No |
| 9 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 5712 | 0.565 | -0.1820 | No |
| 10 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 6033 | 0.476 | -0.1942 | No |
| 11 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 9221 | -0.417 | -0.4148 | No |
| 12 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 9649 | -0.575 | -0.4325 | No |
| 13 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 10170 | -0.812 | -0.4516 | No |
| 14 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 11087 | -1.267 | -0.4890 | Yes |
| 15 | CAT | CAT Entrez, Source | catalase | 11143 | -1.295 | -0.4635 | Yes |
| 16 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 11183 | -1.317 | -0.4364 | Yes |
| 17 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 11319 | -1.391 | -0.4146 | Yes |
| 18 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 11648 | -1.604 | -0.4018 | Yes |
| 19 | GCDH | GCDH Entrez, Source | glutaryl-Coenzyme A dehydrogenase | 11670 | -1.616 | -0.3667 | Yes |
| 20 | AADAT | AADAT Entrez, Source | aminoadipate aminotransferase | 12211 | -2.004 | -0.3601 | Yes |
| 21 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 12333 | -2.105 | -0.3211 | Yes |
| 22 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 12437 | -2.201 | -0.2785 | Yes |
| 23 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 12551 | -2.315 | -0.2341 | Yes |
| 24 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 12595 | -2.351 | -0.1838 | Yes |
| 25 | AFMID | AFMID Entrez, Source | arylformamidase | 12719 | -2.490 | -0.1362 | Yes |
| 26 | OGDHL | OGDHL Entrez, Source | oxoglutarate dehydrogenase-like | 12958 | -2.749 | -0.0909 | Yes |
| 27 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 13336 | -3.229 | -0.0448 | Yes |
| 28 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 13623 | -3.708 | 0.0188 | Yes |
