Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | PID_FANCONI_PATHWAY |
| Enrichment Score (ES) | -0.5768667 |
| Normalized Enrichment Score (NES) | -1.3700122 |
| Nominal p-value | 0.18609408 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | WDR48 | WDR48 Entrez, Source | WD repeat domain 48 | 3929 | 1.170 | -0.2593 | No |
| 2 | HUS1 | HUS1 Entrez, Source | HUS1 checkpoint homolog (S. pombe) | 3971 | 1.155 | -0.2381 | No |
| 3 | FBXW11 | FBXW11 Entrez, Source | F-box and WD-40 domain protein 11 | 4105 | 1.098 | -0.2248 | No |
| 4 | RAD1 | RAD1 Entrez, Source | RAD1 homolog (S. pombe) | 4411 | 0.991 | -0.2261 | No |
| 5 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 6148 | 0.446 | -0.3421 | No |
| 6 | RAD9A | RAD9A Entrez, Source | RAD9 homolog A (S. pombe) | 6382 | 0.384 | -0.3509 | No |
| 7 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 7170 | 0.179 | -0.4040 | No |
| 8 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 7368 | 0.127 | -0.4156 | No |
| 9 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 8422 | -0.159 | -0.4883 | No |
| 10 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 8831 | -0.289 | -0.5117 | No |
| 11 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 9121 | -0.388 | -0.5245 | No |
| 12 | FANCF | FANCF Entrez, Source | Fanconi anemia, complementation group F | 9764 | -0.627 | -0.5577 | No |
| 13 | ATM | ATM Entrez, Source | ataxia telangiectasia mutated (includes complementation groups A, C and D) | 9880 | -0.670 | -0.5520 | No |
| 14 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 10225 | -0.841 | -0.5593 | Yes |
| 15 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 10238 | -0.846 | -0.5425 | Yes |
| 16 | FANCM | FANCM Entrez, Source | Fanconi anemia, complementation group M | 10272 | -0.861 | -0.5269 | Yes |
| 17 | FANCB | FANCB Entrez, Source | Fanconi anemia, complementation group B | 10440 | -0.941 | -0.5193 | Yes |
| 18 | BRIP1 | BRIP1 Entrez, Source | BRCA1 interacting protein C-terminal helicase 1 | 10650 | -1.041 | -0.5126 | Yes |
| 19 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 11329 | -1.395 | -0.5324 | Yes |
| 20 | FANCG | FANCG Entrez, Source | Fanconi anemia, complementation group G | 11402 | -1.444 | -0.5074 | Yes |
| 21 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 11482 | -1.496 | -0.4819 | Yes |
| 22 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 11488 | -1.500 | -0.4509 | Yes |
| 23 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 11578 | -1.556 | -0.4248 | Yes |
| 24 | BLM | BLM Entrez, Source | Bloom syndrome | 11657 | -1.608 | -0.3968 | Yes |
| 25 | UBE2T | UBE2T Entrez, Source | ubiquitin-conjugating enzyme E2T (putative) | 11759 | -1.674 | -0.3691 | Yes |
| 26 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11774 | -1.680 | -0.3351 | Yes |
| 27 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 12003 | -1.841 | -0.3131 | Yes |
| 28 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 12081 | -1.900 | -0.2789 | Yes |
| 29 | TOPBP1 | TOPBP1 Entrez, Source | topoisomerase (DNA) II binding protein 1 | 12261 | -2.048 | -0.2490 | Yes |
| 30 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12369 | -2.139 | -0.2121 | Yes |
| 31 | RFC5 | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 12486 | -2.247 | -0.1735 | Yes |
| 32 | FANCA | FANCA Entrez, Source | Fanconi anemia, complementation group A | 12880 | -2.658 | -0.1463 | Yes |
| 33 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 13033 | -2.836 | -0.0981 | Yes |
| 34 | FANCE | FANCE Entrez, Source | Fanconi anemia, complementation group E | 13499 | -3.476 | -0.0590 | Yes |
| 35 | FANCL | FANCL Entrez, Source | Fanconi anemia, complementation group L | 13776 | -4.148 | 0.0077 | Yes |
