Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 24hr |
| GeneSet | PID_NFKAPPAB_CANONICAL_PATHWAY |
| Enrichment Score (ES) | 0.64432937 |
| Normalized Enrichment Score (NES) | 1.6409826 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.75139374 |
| FWER p-Value | 0.842 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYLD | CYLD Entrez, Source | cylindromatosis (turban tumor syndrome) | 136 | 4.211 | 0.1065 | Yes |
| 2 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 159 | 4.114 | 0.2186 | Yes |
| 3 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 1106 | 2.968 | 0.2324 | Yes |
| 4 | MALT1 | MALT1 Entrez, Source | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 1228 | 2.875 | 0.3031 | Yes |
| 5 | TRAF6 | TRAF6 Entrez, Source | TNF receptor-associated factor 6 | 1338 | 2.771 | 0.3717 | Yes |
| 6 | CHUK | CHUK Entrez, Source | conserved helix-loop-helix ubiquitous kinase | 1473 | 2.661 | 0.4356 | Yes |
| 7 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 1570 | 2.572 | 0.4997 | Yes |
| 8 | IKBKG | IKBKG Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 1616 | 2.544 | 0.5667 | Yes |
| 9 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 1943 | 2.302 | 0.6068 | Yes |
| 10 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 2516 | 1.897 | 0.6180 | Yes |
| 11 | BCL10 | BCL10 Entrez, Source | B-cell CLL/lymphoma 10 | 2812 | 1.724 | 0.6443 | Yes |
| 12 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 3452 | 1.383 | 0.6364 | No |
| 13 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 4727 | 0.874 | 0.5687 | No |
| 14 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 5496 | 0.624 | 0.5305 | No |
| 15 | TNFAIP3 | TNFAIP3 Entrez, Source | tumor necrosis factor, alpha-induced protein 3 | 6627 | 0.323 | 0.4580 | No |
| 16 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 7499 | 0.097 | 0.3978 | No |
| 17 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 8505 | -0.184 | 0.3304 | No |
| 18 | IKBKB | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 8899 | -0.315 | 0.3107 | No |
| 19 | ATM | ATM Entrez, Source | ataxia telangiectasia mutated (includes complementation groups A, C and D) | 9880 | -0.670 | 0.2586 | No |
| 20 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10734 | -1.089 | 0.2271 | No |
