Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 24hr |
| GeneSet | PID_P38_MKK3_6PATHWAY |
| Enrichment Score (ES) | 0.3935281 |
| Normalized Enrichment Score (NES) | 1.606313 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.64154583 |
| FWER p-Value | 0.842 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 768 | 3.335 | 0.0349 | Yes |
| 2 | TRAF6 | TRAF6 Entrez, Source | TNF receptor-associated factor 6 | 1338 | 2.771 | 0.0690 | Yes |
| 3 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 1581 | 2.568 | 0.1211 | Yes |
| 4 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 1624 | 2.537 | 0.1867 | Yes |
| 5 | TXN | TXN Entrez, Source | thioredoxin | 1767 | 2.421 | 0.2421 | Yes |
| 6 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 1833 | 2.377 | 0.3018 | Yes |
| 7 | MAP3K7 | MAP3K7 Entrez, Source | mitogen-activated protein kinase kinase kinase 7 | 2444 | 1.950 | 0.3106 | Yes |
| 8 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 2656 | 1.810 | 0.3445 | Yes |
| 9 | MAP3K4 | MAP3K4 Entrez, Source | mitogen-activated protein kinase kinase kinase 4 | 3116 | 1.550 | 0.3533 | Yes |
| 10 | TAOK2 | TAOK2 Entrez, Source | TAO kinase 2 | 3139 | 1.542 | 0.3935 | Yes |
| 11 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 5083 | 0.760 | 0.2739 | No |
| 12 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 6322 | 0.398 | 0.1954 | No |
| 13 | MAPK11 | MAPK11 Entrez, Source | mitogen-activated protein kinase 11 | 6372 | 0.387 | 0.2024 | No |
| 14 | TAOK1 | TAOK1 Entrez, Source | TAO kinase 1 | 7713 | 0.037 | 0.1067 | No |
| 15 | MAP3K6 | MAP3K6 Entrez, Source | mitogen-activated protein kinase kinase kinase 6 | 9787 | -0.637 | -0.0256 | No |
| 16 | ATM | ATM Entrez, Source | ataxia telangiectasia mutated (includes complementation groups A, C and D) | 9880 | -0.670 | -0.0141 | No |
| 17 | CCM2 | CCM2 Entrez, Source | cerebral cavernous malformation 2 | 9971 | -0.709 | -0.0014 | No |
| 18 | MAP3K5 | MAP3K5 Entrez, Source | mitogen-activated protein kinase kinase kinase 5 | 10586 | -1.013 | -0.0182 | No |
| 19 | MAP3K3 | MAP3K3 Entrez, Source | mitogen-activated protein kinase kinase kinase 3 | 11410 | -1.448 | -0.0384 | No |
| 20 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 11959 | -1.813 | -0.0288 | No |
| 21 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 12981 | -2.769 | -0.0275 | No |
| 22 | CAMK2B | CAMK2B Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II beta | 13464 | -3.413 | 0.0302 | No |
