Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #24hr_versus_0hr.class.cls #24hr_versus_0hr_repos |
| Phenotype | class.cls#24hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | REACTOME_G2_M_CHECKPOINTS |
| Enrichment Score (ES) | -0.6679978 |
| Normalized Enrichment Score (NES) | -1.5982506 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.86 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HUS1 | HUS1 Entrez, Source | HUS1 checkpoint homolog (S. pombe) | 3971 | 1.155 | -0.2628 | No |
| 2 | RAD1 | RAD1 Entrez, Source | RAD1 homolog (S. pombe) | 4411 | 0.991 | -0.2741 | No |
| 3 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 4809 | 0.844 | -0.2853 | No |
| 4 | RAD9A | RAD9A Entrez, Source | RAD9 homolog A (S. pombe) | 6382 | 0.384 | -0.3909 | No |
| 5 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 7170 | 0.179 | -0.4440 | No |
| 6 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 7515 | 0.092 | -0.4669 | No |
| 7 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 8422 | -0.159 | -0.5290 | No |
| 8 | MCM10 | MCM10 Entrez, Source | MCM10 minichromosome maintenance deficient 10 (S. cerevisiae) | 8436 | -0.165 | -0.5266 | No |
| 9 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 9121 | -0.388 | -0.5680 | No |
| 10 | ATM | ATM Entrez, Source | ataxia telangiectasia mutated (includes complementation groups A, C and D) | 9880 | -0.670 | -0.6088 | No |
| 11 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 10238 | -0.846 | -0.6171 | No |
| 12 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 10326 | -0.885 | -0.6052 | No |
| 13 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 11062 | -1.254 | -0.6323 | No |
| 14 | CDC6 | CDC6 Entrez, Source | CDC6 cell division cycle 6 homolog (S. cerevisiae) | 11557 | -1.545 | -0.6361 | Yes |
| 15 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 11578 | -1.556 | -0.6055 | Yes |
| 16 | CDC25C | CDC25C Entrez, Source | cell division cycle 25C | 11628 | -1.588 | -0.5762 | Yes |
| 17 | MCM8 | MCM8 Entrez, Source | MCM8 minichromosome maintenance deficient 8 (S. cerevisiae) | 11772 | -1.678 | -0.5519 | Yes |
| 18 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11774 | -1.680 | -0.5173 | Yes |
| 19 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12024 | -1.856 | -0.4970 | Yes |
| 20 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 12048 | -1.873 | -0.4600 | Yes |
| 21 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 12081 | -1.900 | -0.4231 | Yes |
| 22 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 12275 | -2.058 | -0.3945 | Yes |
| 23 | RFC5 | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 12486 | -2.247 | -0.3633 | Yes |
| 24 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 12496 | -2.255 | -0.3174 | Yes |
| 25 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 12609 | -2.360 | -0.2768 | Yes |
| 26 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12673 | -2.441 | -0.2310 | Yes |
| 27 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 13033 | -2.836 | -0.1984 | Yes |
| 28 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 13051 | -2.863 | -0.1405 | Yes |
| 29 | CDC7 | CDC7 Entrez, Source | CDC7 cell division cycle 7 (S. cerevisiae) | 13103 | -2.934 | -0.0837 | Yes |
| 30 | MCM2 | MCM2 Entrez, Source | MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) | 13166 | -3.018 | -0.0259 | Yes |
| 31 | MCM3 | MCM3 Entrez, Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 13643 | -3.758 | 0.0173 | Yes |
