Datasetdata_collapsed_to_symbols.class.cls
#24hr_versus_0hr.class.cls
#24hr_versus_0hr_repos
Phenotypeclass.cls#24hr_versus_0hr_repos
Upregulated in class24hr
GeneSetREACTOME_HIV_INFECTION
Enrichment Score (ES)0.4699872
Normalized Enrichment Score (NES)1.7065463
Nominal p-value0.0
FDR q-value0.7556433
FWER p-Value0.681
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_HIV_INFECTION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PSMD12PSMD12
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12124.7320.0139Yes
2PSMD6PSMD6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6284.5360.0270Yes
3PSMC4PSMC4
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 4384.4940.0405Yes
4AP1S2AP1S2
Entrez,  Source
adaptor-related protein complex 1, sigma 2 subunit434.4840.0542Yes
5PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 4624.3930.0666Yes
6HMGA1HMGA1
Entrez,  Source
high mobility group AT-hook 11184.2530.0759Yes
7PSMD13PSMD13
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 131654.0940.0854Yes
8VPS37AVPS37A
Entrez,  Source
vacuolar protein sorting 37 homolog A (S. cerevisiae)1944.0440.0960Yes
9PSMC6PSMC6
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 62243.9960.1064Yes
10TCEB3TCEB3
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)2433.9710.1175Yes
11PSMB7PSMB7
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 73273.8440.1235Yes
12AP2B1AP2B1
Entrez,  Source
adaptor-related protein complex 2, beta 1 subunit3403.8110.1346Yes
13PSMC1PSMC1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 13483.7970.1459Yes
14AP1G1AP1G1
Entrez,  Source
adaptor-related protein complex 1, gamma 1 subunit3983.7280.1540Yes
15CCNHCCNH
Entrez,  Source
cyclin H4753.6350.1599Yes
16PSMA1PSMA1
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 14773.6340.1712Yes
17PSMA4PSMA4
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 44903.6210.1816Yes
18PSMC2PSMC2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 25223.5820.1906Yes
19PSMA5PSMA5
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 55553.5430.1994Yes
20PSMD8PSMD8
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 85693.5210.2094Yes
21PSMA3PSMA3
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 36133.4800.2172Yes
22PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 66563.4410.2249Yes
23CTDP1CTDP1
Entrez,  Source
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 17293.3800.2302Yes
24PSMD2PSMD2
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 27343.3720.2405Yes
25PSMD14PSMD14
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 148003.3010.2461Yes
26PSMB4PSMB4
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 48233.2700.2547Yes
27PSMB5PSMB5
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 58413.2510.2636Yes
28PSMA2PSMA2
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 28563.2290.2727Yes
29HLA-AHLA-A
Entrez,  Source
major histocompatibility complex, class I, A8623.2270.2825Yes
30PSMD1PSMD1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 19013.1900.2897Yes
31RNMTRNMT
Entrez,  Source
RNA (guanine-7-) methyltransferase9313.1490.2974Yes
32GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa9643.1140.3048Yes
33ELLELL
Entrez,  Source
elongation factor RNA polymerase II10762.9930.3061Yes
34PSMD11PSMD11
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1111132.9600.3127Yes
35POLR2CPOLR2C
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa11462.9340.3196Yes
36KPNA1KPNA1
Entrez,  Source
karyopherin alpha 1 (importin alpha 5)11722.9170.3269Yes
37PSMD3PSMD3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 312842.8220.3276Yes
38PSMA7PSMA7
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 712892.8170.3362Yes
39PSMC3PSMC3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 313152.7990.3431Yes
40RANBP2RANBP2
Entrez,  Source
RAN binding protein 213352.7740.3504Yes
41RAE1RAE1
Entrez,  Source
RAE1 RNA export 1 homolog (S. pombe)13582.7590.3574Yes
42PSMB3PSMB3
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 313662.7530.3655Yes
43TAF9TAF9
Entrez,  Source
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa13762.7440.3735Yes
44PSMB2PSMB2
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 214632.6740.3756Yes
45SUPT5HSUPT5H
Entrez,  Source
suppressor of Ty 5 homolog (S. cerevisiae)15002.6300.3812Yes
46NUP188NUP188
Entrez,  Source
nucleoporin 188kDa15682.5730.3843Yes
47RANRAN
Entrez,  Source
RAN, member RAS oncogene family15702.5720.3923Yes
48VPS37BVPS37B
Entrez,  Source
vacuolar protein sorting 37 homolog B (S. cerevisiae)16122.5470.3973Yes
49MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)16652.4980.4013Yes
50PSMC5PSMC5
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, ATPase, 517942.4050.3995Yes
51CUL5CUL5
Entrez,  Source
cullin 519582.2920.3948Yes
52TAF4BTAF4B
Entrez,  Source
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa19872.2760.3999Yes
53GTF2E2GTF2E2
Entrez,  Source
general transcription factor IIE, polypeptide 2, beta 34kDa20222.2480.4044Yes
54ARF1ARF1
Entrez,  Source
ADP-ribosylation factor 120682.2120.4081Yes
55RANGAP1RANGAP1
Entrez,  Source
Ran GTPase activating protein 120732.2080.4147Yes
56NUP54NUP54
Entrez,  Source
nucleoporin 54kDa21212.1730.4181Yes
57NUPL1NUPL1
Entrez,  Source
nucleoporin like 121562.1400.4223Yes
58TCEB1TCEB1
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)22452.0810.4224Yes
59GTF2H3GTF2H3
Entrez,  Source
general transcription factor IIH, polypeptide 3, 34kDa23961.9810.4176Yes
60POM121POM121
Entrez,  Source
POM121 membrane glycoprotein (rat)24621.9380.4190Yes
61TBPTBP
Entrez,  Source
TATA box binding protein24701.9280.4245Yes
62PSMB6PSMB6
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 624791.9230.4299Yes
63NUP88NUP88
Entrez,  Source
nucleoporin 88kDa25531.8740.4305Yes
64BTRCBTRC
Entrez,  Source
beta-transducin repeat containing25871.8560.4339Yes
65PSMD4PSMD4
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 427171.7780.4300Yes
66NUP153NUP153
Entrez,  Source
nucleoporin 153kDa27831.7450.4307Yes
67GTF2H2GTF2H2
Entrez,  Source
general transcription factor IIH, polypeptide 2, 44kDa28081.7270.4344Yes
68TCEB2TCEB2
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)28701.6950.4353Yes
69GTF2A1GTF2A1
Entrez,  Source
general transcription factor IIA, 1, 19/37kDa28801.6890.4399Yes
70CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)28951.6800.4441Yes
71PSMD7PSMD7
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)29341.6560.4465Yes
72NUP50NUP50
Entrez,  Source
nucleoporin 50kDa30071.6170.4463Yes
73PSMF1PSMF1
Entrez,  Source
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)30491.5910.4483Yes
74NUP43NUP43
Entrez,  Source
nucleoporin 43kDa30501.5910.4533Yes
75PSMB1PSMB1
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 131691.5270.4495Yes
76POLR2DPOLR2D
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide D31831.5200.4533Yes
77CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)32161.5010.4557Yes
78GTF2F1GTF2F1
Entrez,  Source
general transcription factor IIF, polypeptide 1, 74kDa32481.4850.4580Yes
79FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES32551.4800.4622Yes
80CCNT2CCNT2
Entrez,  Source
cyclin T232601.4750.4666Yes
81PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)32771.4660.4700Yes
82CCNT1CCNT1
Entrez,  Source
cyclin T133931.4060.4660No
83RPS27ARPS27A
Entrez,  Source
ribosomal protein S27a35171.3580.4613No
84NUP155NUP155
Entrez,  Source
nucleoporin 155kDa36351.3020.4568No
85B2MB2M
Entrez,  Source
beta-2-microglobulin37561.2490.4520No
86PSMD9PSMD9
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 938051.2260.4523No
87AP1M1AP1M1
Entrez,  Source
adaptor-related protein complex 1, mu 1 subunit39751.1520.4436No
88GTF2BGTF2B
Entrez,  Source
general transcription factor IIB41491.0800.4343No
89ATP6V1HATP6V1H
Entrez,  Source
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H41971.0640.4342No
90NMT1NMT1
Entrez,  Source
N-myristoyltransferase 142811.0440.4315No
91POLR2BPOLR2B
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa44350.9830.4234No
92GTF2A2GTF2A2
Entrez,  Source
general transcription factor IIA, 2, 12kDa45520.9410.4179No
93NUPL2NUPL2
Entrez,  Source
nucleoporin like 246430.9030.4141No
94UBA52UBA52
Entrez,  Source
ubiquitin A-52 residue ribosomal protein fusion product 146940.8860.4132No
95PSMD5PSMD5
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 547020.8830.4155No
96PSMD10PSMD10
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1047260.8740.4165No
97RNGTTRNGTT
Entrez,  Source
RNA guanylyltransferase and 5'-phosphatase48480.8330.4103No
98NCBP1NCBP1
Entrez,  Source
nuclear cap binding protein subunit 1, 80kDa48560.8300.4124No
99GTF2H1GTF2H1
Entrez,  Source
general transcription factor IIH, polypeptide 1, 62kDa48630.8280.4146No
100KPNB1KPNB1
Entrez,  Source
karyopherin (importin) beta 149090.8160.4138No
101LOC440577LOC440577
Entrez,  Source
-49290.8080.4150No
102POLR2APOLR2A
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa49430.8020.4165No
103POLR2EPOLR2E
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa49600.7990.4179No
104RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)50830.7600.4114No
105ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)53500.6720.3941No
106PAK2PAK2
Entrez,  Source
p21 (CDKN1A)-activated kinase 254590.6370.3882No
107RDBPRDBP
Entrez,  Source
RD RNA binding protein56900.5710.3732No
108GTF2H4GTF2H4
Entrez,  Source
general transcription factor IIH, polypeptide 4, 52kDa57490.5520.3707No
109NUP205NUP205
Entrez,  Source
nucleoporin 205kDa60060.4840.3535No
110TCEA1TCEA1
Entrez,  Source
transcription elongation factor A (SII), 160610.4670.3510No
111BANF1BANF1
Entrez,  Source
barrier to autointegration factor 161650.4420.3449No
112CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 463290.3960.3342No
113AP2A2AP2A2
Entrez,  Source
adaptor-related protein complex 2, alpha 2 subunit63400.3950.3347No
114SUPT4H1SUPT4H1
Entrez,  Source
suppressor of Ty 4 homolog 1 (S. cerevisiae)63760.3860.3334No
115WHSC2WHSC2
Entrez,  Source
Wolf-Hirschhorn syndrome candidate 264760.3620.3273No
116NUP35NUP35
Entrez,  Source
nucleoporin 35kDa65750.3360.3212No
117POLR2GPOLR2G
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide G71560.1840.2795No
118ELMO1ELMO1
Entrez,  Source
engulfment and cell motility 173210.1420.2679No
119TAF1TAF1
Entrez,  Source
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa75180.0910.2539No
120POLR2JPOLR2J
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa75460.0850.2522No
121PACS1PACS1
Entrez,  Source
phosphofurin acidic cluster sorting protein 176600.0500.2441No
122NUP93NUP93
Entrez,  Source
nucleoporin 93kDa76990.0420.2415No
123POLR2KPOLR2K
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa77040.0390.2413No
124LCKLCK
Entrez,  Source
lymphocyte-specific protein tyrosine kinase77580.0240.2375No
125SEH1LSEH1L
Entrez,  Source
SEH1-like (S. cerevisiae)8030-0.0500.2179No
126NMT2NMT2
Entrez,  Source
N-myristoyltransferase 28049-0.0560.2168No
127POLR2IPOLR2I
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa8242-0.1080.2031No
128CD4CD4
Entrez,  Source
CD4 molecule8249-0.1090.2030No
129NUP210NUP210
Entrez,  Source
nucleoporin 210kDa8287-0.1190.2007No
130TSG101TSG101
Entrez,  Source
tumor susceptibility gene 1018317-0.1260.1990No
131XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)8505-0.1840.1859No
132TAF4TAF4
Entrez,  Source
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa8605-0.2130.1793No
133LIG4LIG4
Entrez,  Source
ligase IV, DNA, ATP-dependent8675-0.2380.1750No
134AP2M1AP2M1
Entrez,  Source
adaptor-related protein complex 2, mu 1 subunit8718-0.2500.1728No
135POLR2FPOLR2F
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide F8796-0.2760.1680No
136AP2A1AP2A1
Entrez,  Source
adaptor-related protein complex 2, alpha 1 subunit8997-0.3480.1545No
137AP2S1AP2S1
Entrez,  Source
adaptor-related protein complex 2, sigma 1 subunit9065-0.3710.1508No
138VPS37DVPS37D
Entrez,  Source
vacuolar protein sorting 37 homolog D (S. cerevisiae)9143-0.3960.1464No
139COBRA1COBRA1
Entrez,  Source
-9282-0.4370.1377No
140NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)9295-0.4410.1382No
141XRCC4XRCC4
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 49308-0.4490.1387No
142NCBP2NCBP2
Entrez,  Source
nuclear cap binding protein subunit 2, 20kDa9426-0.4940.1317No
143CCR5CCR5
Entrez,  Source
chemokine (C-C motif) receptor 59439-0.4990.1324No
144VPS37CVPS37C
Entrez,  Source
vacuolar protein sorting 37 homolog C (S. cerevisiae)9604-0.5530.1222No
145XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)9693-0.5920.1176No
146RBX1RBX1
Entrez,  Source
ring-box 19795-0.6390.1123No
147POLR2LPOLR2L
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa9866-0.6660.1092No
148TAF12TAF12
Entrez,  Source
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa9879-0.6700.1105No
149PPIAPPIA
Entrez,  Source
peptidylprolyl isomerase A (cyclophilin A)10028-0.7420.1020No
150AAASAAAS
Entrez,  Source
achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)10106-0.7800.0988No
151TAF11TAF11
Entrez,  Source
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa10301-0.8760.0874No
152NUP37NUP37
Entrez,  Source
nucleoporin 37kDa10335-0.8910.0878No
153PSMB8PSMB8
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)10444-0.9420.0828No
154AP1M2AP1M2
Entrez,  Source
adaptor-related protein complex 1, mu 2 subunit10480-0.9610.0833No
155SLC25A6SLC25A6
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 610490-0.9640.0857No
156PSIP1PSIP1
Entrez,  Source
PC4 and SFRS1 interacting protein 110589-1.0160.0817No
157SUPT16HSUPT16H
Entrez,  Source
suppressor of Ty 16 homolog (S. cerevisiae)10688-1.0610.0779No
158AP1S1AP1S1
Entrez,  Source
adaptor-related protein complex 1, sigma 1 subunit10696-1.0660.0807No
159ERCC2ERCC2
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)10743-1.0940.0808No
160GTF2E1GTF2E1
Entrez,  Source
general transcription factor IIE, polypeptide 1, alpha 56kDa11171-1.3120.0537No
161TH1LTH1L
Entrez,  Source
TH1-like (Drosophila)11317-1.3890.0475No
162VPS28VPS28
Entrez,  Source
vacuolar protein sorting 28 homolog (S. cerevisiae)11496-1.5020.0392No
163TPRTPR
Entrez,  Source
translocated promoter region (to activated MET oncogene)11623-1.5850.0350No
164SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 411635-1.5950.0391No
165SSRP1SSRP1
Entrez,  Source
structure specific recognition protein 111645-1.6020.0435No
166NUP133NUP133
Entrez,  Source
nucleoporin 133kDa12087-1.9040.0173No
167RANBP1RANBP1
Entrez,  Source
RAN binding protein 112090-1.9070.0231No
168FEN1FEN1
Entrez,  Source
flap structure-specific endonuclease 112296-2.0730.0146No
169HCKHCK
Entrez,  Source
hemopoietic cell kinase12354-2.1270.0171No
170NUP62NUP62
Entrez,  Source
nucleoporin 62kDa12425-2.1930.0189No
171TAF10TAF10
Entrez,  Source
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa12659-2.4260.0095No
172TAF6TAF6
Entrez,  Source
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa12723-2.4970.0127No
173PSMB10PSMB10
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 1012778-2.5440.0167No
174NUP107NUP107
Entrez,  Source
nucleoporin 107kDa12802-2.5690.0231No
175LIG1LIG1
Entrez,  Source
ligase I, DNA, ATP-dependent13041-2.8510.0147No
176PSME1PSME1
Entrez,  Source
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)13345-3.2430.0027No
177SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 513487-3.4570.0032No
178PSME2PSME2
Entrez,  Source
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)13728-3.982-0.0018No
179POLR2HPOLR2H
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide H13782-4.1660.0074No
Table: GSEA details [plain text format]



Fig 2: REACTOME_HIV_INFECTION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_HIV_INFECTION: Random ES distribution   
Gene set null distribution of ES for REACTOME_HIV_INFECTION