Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | GHANDHI_BYSTANDER_IRRADIATION_UP |
| Enrichment Score (ES) | 0.52977324 |
| Normalized Enrichment Score (NES) | 1.792805 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.54174614 |
| FWER p-Value | 0.557 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 36 | 4.080 | 0.0908 | Yes |
| 2 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 93 | 3.680 | 0.1710 | Yes |
| 3 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 229 | 3.167 | 0.2337 | Yes |
| 4 | SLC7A11 | SLC7A11 Entrez, Source | solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 | 487 | 2.616 | 0.2750 | Yes |
| 5 | MCTP2 | MCTP2 Entrez, Source | multiple C2 domains, transmembrane 2 | 608 | 2.440 | 0.3222 | Yes |
| 6 | LIF | LIF Entrez, Source | leukemia inhibitory factor (cholinergic differentiation factor) | 867 | 2.106 | 0.3518 | Yes |
| 7 | ZCCHC6 | ZCCHC6 Entrez, Source | zinc finger, CCHC domain containing 6 | 990 | 1.982 | 0.3883 | Yes |
| 8 | SLC39A14 | SLC39A14 Entrez, Source | solute carrier family 39 (zinc transporter), member 14 | 1183 | 1.796 | 0.4156 | Yes |
| 9 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 1248 | 1.743 | 0.4508 | Yes |
| 10 | LRRC8B | LRRC8B Entrez, Source | leucine rich repeat containing 8 family, member B | 1434 | 1.580 | 0.4736 | Yes |
| 11 | CXCL3 | CXCL3 Entrez, Source | chemokine (C-X-C motif) ligand 3 | 1562 | 1.475 | 0.4982 | Yes |
| 12 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 1588 | 1.458 | 0.5298 | Yes |
| 13 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 2450 | 1.010 | 0.4907 | No |
| 14 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 3448 | 0.703 | 0.4347 | No |
| 15 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 3979 | 0.573 | 0.4095 | No |
| 16 | LOC284454 | LOC284454 Entrez, Source | - | 4159 | 0.536 | 0.4089 | No |
| 17 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 4347 | 0.497 | 0.4067 | No |
| 18 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 4440 | 0.476 | 0.4110 | No |
| 19 | RELB | RELB Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian) | 4498 | 0.464 | 0.4175 | No |
| 20 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 4771 | 0.406 | 0.4071 | No |
| 21 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 5049 | 0.357 | 0.3953 | No |
| 22 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 5451 | 0.284 | 0.3728 | No |
| 23 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 5900 | 0.209 | 0.3452 | No |
| 24 | PHEX | PHEX Entrez, Source | phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) | 7068 | 0.027 | 0.2615 | No |
| 25 | ZC3H12C | ZC3H12C Entrez, Source | zinc finger CCCH-type containing 12C | 7106 | 0.023 | 0.2594 | No |
| 26 | EPB41L4B | EPB41L4B Entrez, Source | erythrocyte membrane protein band 4.1 like 4B | 7240 | 0.004 | 0.2498 | No |
| 27 | CCK | CCK Entrez, Source | cholecystokinin | 7343 | -0.011 | 0.2427 | No |
| 28 | NFKBIZ | NFKBIZ Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 7745 | -0.075 | 0.2155 | No |
| 29 | TNFAIP3 | TNFAIP3 Entrez, Source | tumor necrosis factor, alpha-induced protein 3 | 7870 | -0.096 | 0.2087 | No |
| 30 | B3GNT5 | B3GNT5 Entrez, Source | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 7916 | -0.103 | 0.2078 | No |
| 31 | CREB5 | CREB5 Entrez, Source | cAMP responsive element binding protein 5 | 8034 | -0.121 | 0.2021 | No |
| 32 | POPDC3 | POPDC3 Entrez, Source | popeye domain containing 3 | 8931 | -0.268 | 0.1435 | No |
| 33 | MT1L | MT1L Entrez, Source | metallothionein 1L (pseudogene) | 9033 | -0.285 | 0.1427 | No |
| 34 | MT1E | MT1E Entrez, Source | metallothionein 1E (functional) | 9274 | -0.324 | 0.1328 | No |
| 35 | MT1B | MT1B Entrez, Source | metallothionein 1B (functional) | 9737 | -0.398 | 0.1085 | No |
| 36 | MT1X | MT1X Entrez, Source | metallothionein 1X | 9837 | -0.420 | 0.1110 | No |
| 37 | GPR68 | GPR68 Entrez, Source | G protein-coupled receptor 68 | 9924 | -0.434 | 0.1147 | No |
| 38 | MT1G | MT1G Entrez, Source | metallothionein 1G | 10044 | -0.455 | 0.1165 | No |
| 39 | SLC16A3 | SLC16A3 Entrez, Source | solute carrier family 16, member 3 (monocarboxylic acid transporter 4) | 10138 | -0.471 | 0.1206 | No |
| 40 | STC1 | STC1 Entrez, Source | stanniocalcin 1 | 11198 | -0.695 | 0.0600 | No |
| 41 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 11391 | -0.751 | 0.0633 | No |
| 42 | SLC39A8 | SLC39A8 Entrez, Source | solute carrier family 39 (zinc transporter), member 8 | 11475 | -0.777 | 0.0751 | No |
| 43 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 12209 | -1.009 | 0.0452 | No |
| 44 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 12297 | -1.048 | 0.0629 | No |
| 45 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 13613 | -2.255 | 0.0195 | No |
