Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | HUANG_DASATINIB_RESISTANCE_DN |
| Enrichment Score (ES) | -0.5929526 |
| Normalized Enrichment Score (NES) | -1.6157624 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.947 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDC42SE1 | CDC42SE1 Entrez, Source | CDC42 small effector 1 | 767 | 2.221 | -0.0123 | No |
| 2 | EIF4E3 | EIF4E3 Entrez, Source | eukaryotic translation initiation factor 4E member 3 | 1722 | 1.367 | -0.0547 | No |
| 3 | SPIN1 | SPIN1 Entrez, Source | - | 1858 | 1.302 | -0.0391 | No |
| 4 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 2068 | 1.180 | -0.0313 | No |
| 5 | YME1L1 | YME1L1 Entrez, Source | YME1-like 1 (S. cerevisiae) | 2431 | 1.017 | -0.0377 | No |
| 6 | CA12 | CA12 Entrez, Source | carbonic anhydrase XII | 3849 | 0.608 | -0.1283 | No |
| 7 | ARX | ARX Entrez, Source | aristaless related homeobox | 3886 | 0.598 | -0.1193 | No |
| 8 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 5162 | 0.337 | -0.2049 | No |
| 9 | EPB41L5 | EPB41L5 Entrez, Source | erythrocyte membrane protein band 4.1 like 5 | 6710 | 0.084 | -0.3151 | No |
| 10 | VPS37C | VPS37C Entrez, Source | vacuolar protein sorting 37 homolog C (S. cerevisiae) | 6871 | 0.060 | -0.3255 | No |
| 11 | EPS15L1 | EPS15L1 Entrez, Source | epidermal growth factor receptor pathway substrate 15-like 1 | 6899 | 0.056 | -0.3264 | No |
| 12 | GREB1 | GREB1 Entrez, Source | - | 7444 | -0.027 | -0.3652 | No |
| 13 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 7762 | -0.078 | -0.3866 | No |
| 14 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 8022 | -0.119 | -0.4030 | No |
| 15 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 8069 | -0.126 | -0.4039 | No |
| 16 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 8112 | -0.132 | -0.4044 | No |
| 17 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 8240 | -0.153 | -0.4106 | No |
| 18 | KIAA1324 | KIAA1324 Entrez, Source | KIAA1324 | 8473 | -0.192 | -0.4236 | No |
| 19 | STARD10 | STARD10 Entrez, Source | START domain containing 10 | 8845 | -0.255 | -0.4455 | No |
| 20 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 9220 | -0.314 | -0.4664 | No |
| 21 | PLCB4 | PLCB4 Entrez, Source | phospholipase C, beta 4 | 9290 | -0.327 | -0.4650 | No |
| 22 | ICA1 | ICA1 Entrez, Source | islet cell autoantigen 1, 69kDa | 9392 | -0.343 | -0.4657 | No |
| 23 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 9398 | -0.344 | -0.4594 | No |
| 24 | CBX5 | CBX5 Entrez, Source | chromobox homolog 5 (HP1 alpha homolog, Drosophila) | 9801 | -0.413 | -0.4804 | No |
| 25 | ABHD11 | ABHD11 Entrez, Source | abhydrolase domain containing 11 | 11262 | -0.715 | -0.5720 | No |
| 26 | CLDN3 | CLDN3 Entrez, Source | claudin 3 | 11328 | -0.732 | -0.5625 | No |
| 27 | GPD1L | GPD1L Entrez, Source | glycerol-3-phosphate dehydrogenase 1-like | 11373 | -0.746 | -0.5512 | No |
| 28 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 11424 | -0.761 | -0.5400 | No |
| 29 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 12157 | -0.990 | -0.5737 | Yes |
| 30 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 12209 | -1.009 | -0.5578 | Yes |
| 31 | SLC1A2 | SLC1A2 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 12275 | -1.038 | -0.5423 | Yes |
| 32 | SLC25A15 | SLC25A15 Entrez, Source | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 12365 | -1.075 | -0.5279 | Yes |
| 33 | PDCD4 | PDCD4 Entrez, Source | programmed cell death 4 (neoplastic transformation inhibitor) | 12449 | -1.111 | -0.5123 | Yes |
| 34 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 12455 | -1.116 | -0.4909 | Yes |
| 35 | PLEKHH1 | PLEKHH1 Entrez, Source | pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 | 12588 | -1.180 | -0.4775 | Yes |
| 36 | ABCA3 | ABCA3 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 3 | 12790 | -1.276 | -0.4673 | Yes |
| 37 | TFF1 | TFF1 Entrez, Source | trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in) | 12844 | -1.310 | -0.4456 | Yes |
| 38 | CHPT1 | CHPT1 Entrez, Source | choline phosphotransferase 1 | 12887 | -1.333 | -0.4228 | Yes |
| 39 | TPD52 | TPD52 Entrez, Source | tumor protein D52 | 12902 | -1.343 | -0.3977 | Yes |
| 40 | CYB561 | CYB561 Entrez, Source | cytochrome b-561 | 13002 | -1.421 | -0.3772 | Yes |
| 41 | JPH1 | JPH1 Entrez, Source | junctophilin 1 | 13021 | -1.434 | -0.3507 | Yes |
| 42 | PREX1 | PREX1 Entrez, Source | - | 13025 | -1.437 | -0.3230 | Yes |
| 43 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 13104 | -1.512 | -0.2992 | Yes |
| 44 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 13125 | -1.532 | -0.2709 | Yes |
| 45 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 13266 | -1.684 | -0.2483 | Yes |
| 46 | ASCL2 | ASCL2 Entrez, Source | achaete-scute complex-like 2 (Drosophila) | 13386 | -1.841 | -0.2211 | Yes |
| 47 | ISOC1 | ISOC1 Entrez, Source | isochorismatase domain containing 1 | 13405 | -1.861 | -0.1862 | Yes |
| 48 | CREB3L4 | CREB3L4 Entrez, Source | cAMP responsive element binding protein 3-like 4 | 13439 | -1.916 | -0.1514 | Yes |
| 49 | TRPS1 | TRPS1 Entrez, Source | trichorhinophalangeal syndrome I | 13492 | -1.990 | -0.1165 | Yes |
| 50 | IRX5 | IRX5 Entrez, Source | iroquois homeobox protein 5 | 13694 | -2.481 | -0.0828 | Yes |
| 51 | SLC35A1 | SLC35A1 Entrez, Source | solute carrier family 35 (CMP-sialic acid transporter), member A1 | 13882 | -4.958 | 0.0001 | Yes |
