Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | ONGUSAHA_TP53_TARGETS |
| Enrichment Score (ES) | 0.55524105 |
| Normalized Enrichment Score (NES) | 1.7912621 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.51397157 |
| FWER p-Value | 0.557 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 8 | 4.549 | 0.1304 | Yes |
| 2 | MDM2 | MDM2 Entrez, Source | Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) | 87 | 3.712 | 0.2316 | Yes |
| 3 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 118 | 3.583 | 0.3325 | Yes |
| 4 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 251 | 3.115 | 0.4126 | Yes |
| 5 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 415 | 2.745 | 0.4799 | Yes |
| 6 | PHLDA3 | PHLDA3 Entrez, Source | pleckstrin homology-like domain, family A, member 3 | 627 | 2.403 | 0.5338 | Yes |
| 7 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 1095 | 1.884 | 0.5543 | Yes |
| 8 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 1647 | 1.414 | 0.5552 | Yes |
| 9 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 2911 | 0.846 | 0.4884 | No |
| 10 | PLTP | PLTP Entrez, Source | phospholipid transfer protein | 3100 | 0.796 | 0.4978 | No |
| 11 | EFS | EFS Entrez, Source | embryonal Fyn-associated substrate | 3103 | 0.796 | 0.5205 | No |
| 12 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 3397 | 0.716 | 0.5200 | No |
| 13 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 3458 | 0.700 | 0.5358 | No |
| 14 | TNFRSF18 | TNFRSF18 Entrez, Source | tumor necrosis factor receptor superfamily, member 18 | 3833 | 0.611 | 0.5264 | No |
| 15 | MATN4 | MATN4 Entrez, Source | matrilin 4 | 5520 | 0.271 | 0.4125 | No |
| 16 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 5928 | 0.206 | 0.3891 | No |
| 17 | PITPNC1 | PITPNC1 Entrez, Source | phosphatidylinositol transfer protein, cytoplasmic 1 | 6160 | 0.171 | 0.3773 | No |
| 18 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 6230 | 0.162 | 0.3770 | No |
| 19 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 8037 | -0.122 | 0.2501 | No |
| 20 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 8134 | -0.136 | 0.2471 | No |
| 21 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 8301 | -0.164 | 0.2398 | No |
| 22 | ERCC5 | ERCC5 Entrez, Source | me)) | 8541 | -0.206 | 0.2285 | No |
| 23 | ROBO1 | ROBO1 Entrez, Source | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 8751 | -0.238 | 0.2202 | No |
| 24 | PERP | PERP Entrez, Source | PERP, TP53 apoptosis effector | 8771 | -0.242 | 0.2258 | No |
| 25 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 9213 | -0.313 | 0.2030 | No |
| 26 | CTSH | CTSH Entrez, Source | cathepsin H | 9512 | -0.363 | 0.1919 | No |
| 27 | CTSF | CTSF Entrez, Source | cathepsin F | 9515 | -0.363 | 0.2022 | No |
| 28 | PQLC3 | PQLC3 Entrez, Source | PQ loop repeat containing 3 | 12404 | -1.091 | 0.0252 | No |
| 29 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12519 | -1.145 | 0.0499 | No |
| 30 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 13266 | -1.684 | 0.0445 | No |
